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  1. 22541
    por LI, SHA, SUN, YANLAI, GAO, DONGWEI
    Publicado 2013
    “…Disruption of circadian rhythms will also promote cancer metastasis through direct and indirect actions of the nervous system. …”
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    Role of the nervous system in cancer metastasis
  2. 22542
    “…Optimization of frq codon usage abolishes both overt and molecular circadian rhythms. Codon optimization not only increases FRQ level but surprisingly, also results in conformational changes in FRQ protein, altered FRQ phosphorylation profile and stability, and impaired functions in the circadian feedback loops. …”
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    Non-optimal codon usage affects expression, structure and function of FRQ clock protein
  3. 22543
    “…We studied five dynamic models (of the cAMP pathway, the glycolysis, the circadian rhythms, the cell cycle, and heart cell dynamics). …”
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    Effect of Regulatory Architecture on Broad versus Narrow Sense Heritability
  4. 22544
    “…We video-recorded 141 individuals across 71 primate species and analyzed the blink rate, blink duration, and “isolated” blink ratio (i.e., blinks without eye or head movement) in relation to activity rhythms, habitat types, group size, and body size factors. …”
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    Eye-Blink Behaviors in 71 Species of Primates
  5. 22545
    “…The circadian clock orchestrates temporal patterns of physiology and behavior relative to the environmental light:dark cycle by generating and organizing transcriptional and biochemical rhythms in cells and tissues throughout the body. …”
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    Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation
  6. 22546
    “…Finally, we discuss how this concept might be relevant to a better understanding of pathological conditions with impaired melatonin rhythms and hope it opens new horizons for the research of side effects of melatonin-based therapies.…”
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    Immune-Pineal Axis: Nuclear Factor κB (NF-κB) Mediates the Shift in the Melatonin Source from Pinealocytes to Immune Competent Cells
  7. 22547
    por Chen, Weihan, Hillyer, Julián F.
    Publicado 2013
    “…Specifically, they confirm that the neurohormone CCAP modulates heart rhythms and that it serves as an anterograde pacemaker.…”
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    FlyNap (Triethylamine) Increases the Heart Rate of Mosquitoes and Eliminates the Cardioacceleratory Effect of the Neuropeptide CCAP
  8. 22548
    “…Tissue ILC2 regulate basal eosinophilopoiesis and tissue eosinophil accumulation through constitutive and stimulated cytokine expression, and this dissociated regulation can be tuned by nutrient intake and central circadian rhythms.…”
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    Type 2 innate lymphoid cells control eosinophil homeostasis
  9. 22549
    por Kitada, Munehiro, Koya, Daisuke
    Publicado 2013
    “…SIRT1 also regulates adiponectin secretion, inflammation, glucose production, oxidative stress, mitochondrial function, and circadian rhythms. Several SIRT1 activators, including resveratrol have been demonstrated to have beneficial effects on glucose homeostasis and insulin sensitivity in animal models of insulin resistance. …”
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    SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential
  10. 22550
    por Lee, Youngseok
    Publicado 2013
    “…Here, I used the bacterial sodium channel, NaChBac, to examine the effects of altering the electrical properties of trpA1 neurons on circadian rhythms. My results indicate that circadian activity of the flies in the morning, daytime, and evening was affected in a temperature-dependent manner following TRPA1 neuronal activation. …”
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    Contribution of Drosophila TRPA1-Expressing Neurons to Circadian Locomotor Activity Patterns
  11. 22551
    “…This CHH transcript synchronized to daily light-dark cycles and oscillated under dark, constant conditions demonstrating statistically significant daily and circadian rhythms in both structures. Furthermore, to investigate the presence of the peptide in the central brain of this decapod, we used immunohistochemical methods. …”
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    Putative Pacemakers in the Eyestalk and Brain of the Crayfish Procambarus clarkii Show Circadian Oscillations in Levels of mRNA for Crustacean Hyperglycemic Hormone
  12. 22552
    “…Recent studies exploring the molecular genetic basis for migratory variation in animals have identified polymorphisms in two genes ( CLOCK and ADCYAP1) that are linked to circadian rhythms and correlate with migratory propensity and phenology among individuals and populations. …”
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    Variation in candidate genes CLOCK and ADCYAP1 does not consistently predict differences in migratory behavior in the songbird genus Junco
  13. 22553
    por Shiue, Ivy
    Publicado 2014
    “…After full adjustment, it was observed that being exposed to indoor passive smoking, in particular in more than two places of exposure, was significantly associated with risks of stroke, angina, heart attack, abnormal heart rhythms, and GHQ ≥ 12. The significance remained for angina, GHQ ≥ 12 and probably heart attack in never smokers. …”
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    Modeling the Effects of Indoor Passive Smoking at Home, Work, or Other Households on Adult Cardiovascular and Mental Health: The Scottish Health Survey, 2008–2011
  14. 22554
    “…Circadian rhythms are controlled by a system of negative and positive genetic feedback loops composed of clock genes. …”
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    A Novel Protein, CHRONO, Functions as a Core Component of the Mammalian Circadian Clock
  15. 22555
    “…Genetic disruption of CK1ε in mice enhances phase resetting of behavioral rhythms to acute light pulses and shifts in light cycle. …”
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    A Novel Mechanism Controlling Resetting Speed of the Circadian Clock to Environmental Stimuli
  16. 22556
    “…BACKGROUND: This study examined how ethnic differences in sleep and depression were related to environmental illumination and circadian rhythms. METHODS: In an ancillary study to the Women's Health Initiative, 459 postmenopausal women were recorded for one week in their homes, using wrist monitors. …”
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    Ethnicity, sleep, mood, and illumination in postmenopausal women
  17. 22557
    “…In rodents, daily feeding schedules induce food anticipatory activity (FAA) rhythms with formal properties suggesting mediation by food-entrained circadian oscillators (FEOs). …”
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    Behavioral and Neural Correlates of Acute and Scheduled Hunger in C57BL/6 Mice
  18. 22558
    “…These observations provide a positive perspective and a basis for future implementation of a very large scale biologically plausible model of thalamo-cortico-thalamic interactivity—the essential brain circuit that regulates the biological sleep-wake cycle and associated EEG rhythms.…”
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    Engineering a thalamo-cortico-thalamic circuit on SpiNNaker: a preliminary study toward modeling sleep and wakefulness
  19. 22559
    “…Because light functions as an important synchronizing signal for circadian rhythms, we further investigated the effects of both hormones on genes related to the circadian system, namely, Per1 (one of the clock genes) and the melanopsins, Opn4x and Opn4m (photopigments). …”
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    Regulation of Melanopsins and Per1 by α-MSH and Melatonin in Photosensitive Xenopus laevis Melanophores
  20. 22560
    “…Chronotype is an established concept designed to identify distinct phase relationships between the expression of circadian rhythms and external synchronizers in humans. Although it has been widely accepted that chronotype is subjected to ontogenetic modulation, there is no consensus on the interaction between age and gender. …”
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    Chronotype ontogeny related to gender
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