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  1. 21221
    “…The circadian clock is accountable for the regulation of internal rhythms in most living organisms. It allows the anticipation of environmental changes during the day and a better adaptation of physiological processes. …”
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    Tuning the Mammalian Circadian Clock: Robust Synergy of Two Loops
  2. 21222
    “…Disrupting maternal circadian rhythms through exposure to chronic phase shifts of the photoperiod has lifelong consequences for the metabolic homeostasis of the fetus, such that offspring develop increased adiposity, hyperinsulinaemia and poor glucose and insulin tolerance. …”
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    Characterisation of the Maternal Response to Chronic Phase Shifts during Gestation in the Rat: Implications for Fetal Metabolic Programming
  3. 21223
    “…We apply the model to reproduce the modulation of gamma rhythms by theta rhythms as has been observed in animal models and human ECoG and EEG studies. …”
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    Top-Down Influences on Local Networks: Basic Theory with Experimental Implications
  4. 21224
    “…Circadian rhythms are fundamental to life. In mammals, these rhythms are generated by pacemaker neurons in the suprachiasmatic nucleus (SCN) of the hypothalamus. …”
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    Mammalian Rest/Activity Patterns Explained by Physiologically Based Modeling
  5. 21225
    “…Despite quasi-normal circadian transcriptional rhythms, tim-fbl flies display brain-specific aberrant circadian locomotor rhythms, and a unique transcriptional signature. …”
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    A new in vivo model of pantothenate kinase-associated neurodegeneration reveals a surprising role for transcriptional regulation in pathogenesis
  6. 21226
    “…Furthermore, during light-phase restricted feeding, repeated dosing of exendin-4 at the beginning of the dark phase profoundly influenced both the food intake and daily rhythms of clock gene expression in peripheral tissues. …”
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    Indirect Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Peripheral Circadian Clocks in Mice
  7. 21227
    “…In animals, circadian rhythms in physiology and behavior result from coherent rhythmic interactions between clocks in the brain and those throughout the body. …”
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    Cell Type-Specific Functions of Period Genes Revealed by Novel Adipocyte and Hepatocyte Circadian Clock Models
  8. 21228
    “…After further replication and identification of the causal polymorphisms, these findings may point to future treatments for DSPS, non-24-hour rhythms, and possibly bipolar disorder or depression.…”
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    Circadian Polymorphisms in Night Owls, in Bipolars, and in Non-24-Hour Sleep Cycles
  9. 21229
    por Eggermont, Jos J., Tass, Peter A.
    Publicado 2015
    “…Noise-induced hearing loss, often resulting in tinnitus, causes a reorganization of the tonotopic map in auditory cortex and increased spontaneous firing rates and neural synchrony. Spontaneous brain rhythms rely on neural synchrony. Abnormal neural synchrony in tinnitus appears to be confined to specific frequency bands of brain rhythms. …”
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    Maladaptive Neural Synchrony in Tinnitus: Origin and Restoration
  10. 21230
    “…To determine whether circadian rhythms of the plasma antioxidants (Mel, GSH-Px and SOD) are affected by RF, we performed a study on male Sprague Dawley rats exposed to the 1.8 GHz RF. …”
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    Circadian Rhythmicity of Antioxidant Markers in Rats Exposed to 1.8 GHz Radiofrequency Fields
  11. 21231
    “…Normally, daily 24-h rhythms in physiological processes are controlled by the central clock in the brain in close collaboration with peripheral clocks present throughout the body. …”
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    Rodent models to study the metabolic effects of shiftwork in humans
  12. 21232
    “…Here, we show that the knock-down of a regulator (spag) of the circadian kinase Dbt in circadian cells lowers Dbt levels abnormally, lengthens circadian rhythms and causes expression of activated initiator caspase (Dronc) in the optic lobes during the middle of the day or after light pulses at night. …”
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    Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy
  13. 21233
    “…Estimated 24-hour IOP rhythms using the two devices should not be considered interchangeable.…”
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    Estimation of 24-Hour Intraocular Pressure Peak Timing and Variation Using a Contact Lens Sensor
  14. 21234
    “…Finally, we hypothesize that the unperturbed clock is highly optimized for robust rhythms, as very few gene perturbations are capable of simultaneously increasing amplitude and lowering stochastic noise. …”
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    Quantifying Stochastic Noise in Cultured Circadian Reporter Cells
  15. 21235
    “…Circadian rhythms are oscillations in behavior, metabolism and physiology that have a period close to 24 h. …”
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    “The Environment is Everything That Isn't Me”: Molecular Mechanisms and Evolutionary Dynamics of Insect Clocks in Variable Surroundings
  16. 21236
    “…Disruption of circadian rhythms results in metabolic dysfunction. Casein kinase 1 epsilon (CK1ε) is a canonical circadian clock gene. …”
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    Altered Body Weight Regulation in CK1ε Null and tau Mutant Mice on Regular Chow and High Fat Diets
  17. 21237
    “…We have previously reported ChrA, but not ChrD, to induce forced desynchronization of locomotor activity rhythms in mice (Casiraghi et al. 2012). Body weight was rapidly increased under ChrA, with animals tripling the mean weight gain observed in controls by day 10, and doubling it by day 30 (6% vs. 2%, and 15% vs. 7%, respectively). …”
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    Effects of chronic forced circadian desynchronization on body weight and metabolism in male mice
  18. 21238
    “…In summary, we found markers of robust circadian rhythms, namely high stability, reduced fragmentation, high amplitude, phase advance and low internal desynchronization, were correlated with a reduced PLR to 460–490 nm wavelengths. …”
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    Relationship between Human Pupillary Light Reflex and Circadian System Status
  19. 21239
    “…Although the basic circannual and circadian rhythms of songbirds, their adaptation to migration, and the factors influencing the birds’ day-to-day departure decision are reasonably well studied, we do not understand how birds time their departures within the night. …”
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    Towards a conceptual framework for explaining variation in nocturnal departure time of songbird migrants
  20. 21240
    “…Daily rhythms play a key role in transcriptome regulation in plants and microalgae orchestrating responses that, among other processes, anticipate light transitions that are essential for their metabolism and development. …”
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    Evolution of Daily Gene Co-expression Patterns from Algae to Plants
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