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  1. 21241
    “…In depression, disrupted circadian rhythms reflect abnormalities in the central circadian pacemaker, the hypothalamic suprachiasmatic nucleus (SCN). …”
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    Increased glutamic acid decarboxylase expression in the hypothalamic suprachiasmatic nucleus in depression
  2. 21242
    “…Thirty-eight percent of metabolites exhibited daily rhythms in at least 1 study group, and where a metabolite was rhythmic in >1 group, its peak time was comparable. …”
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    Twenty-four-hour rhythmicity of circulating metabolites: effect of body mass and type 2 diabetes
  3. 21243
    “…Circadian clocks consist of molecular negative feedback loops that coordinate physiological, neurological, and behavioral variables into “circa” 24-h rhythms. Rhythms in behavioral and other circadian outputs tend to weaken during aging, as evident in progressive disruptions of sleep-wake cycles in aging organisms. …”
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    Age-Related Changes in the Expression of the Circadian Clock Protein PERIOD in Drosophila Glial Cells
  4. 21244
    “…The results revealed that the circadian clock genes such as Bmal1, Clock, Per1, and Cry2 displayed circadian rhythms in hen livers. The genes related to circulating nutrient transportation, lipogenesis, lipid catabolism, sterol metabolism, and oxidative/anti-oxidative systems also oscillated. …”
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    Integrated hepatic transcriptional and serum metabolic studies on circulating nutrient metabolism in diurnal laying hens
  5. 21245
    “…The ubiquitous daily rhythms in mammalian physiology are guided by progression of the circadian clock. …”
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    Evidence for widespread dysregulation of circadian clock progression in human cancer
  6. 21246
    “…Quantitative changes in task-related coherence in sensorimotor rhythms were compared to the residual motor deficit. …”
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    Parietofrontal network upregulation after motor stroke
  7. 21247
    “…Disruption of the circadian rhythms is a frequent preclinical and clinical manifestation of Alzheimer’s disease. …”
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    Melatonin receptor type 1A gene linked to Alzheimer’s disease in old age
  8. 21248
    “…To determine how circadian clocks respond to metabolic rhythms, we investigated the mechanisms by which sugars adjust the circadian phase in Arabidopsis [5]. …”
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    Circadian Entrainment in Arabidopsis by the Sugar-Responsive Transcription Factor bZIP63
  9. 21249
    “…RESULTS: In vivo assays revealed several circadian abnormalities including lengthened period and instability of behavioral rhythms, and elevated metabolic rate. Grossly aberrant responses to light included accentuated resetting, accelerated re-entrainment, and an absence of locomotor suppression. …”
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    Circadian Disruptions in the Myshkin Mouse Model of Mania Are Independent of Deficits in Suprachiasmatic Molecular Clock Function
  10. 21250
    “…Future research investigating pharmacological and lifestyle interventions by which circadian rhythms within adult stem niches can be manipulated will provide avenues for temporally guided cellular therapies and smart biomaterials to ameliorate age-related tissue deterioration and reduce the burden of chronic disease.…”
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    Adult stem cell maintenance and tissue regeneration around the clock: do impaired stem cell clocks drive age-associated tissue degeneration?
  11. 21251
    “…CONCLUSIONS: The findings of our study suggest that the usefulness of cueing strategies during gait training consists of a reshape of sensorimotor rhythms and fronto-centroparietal/temporal connectivity. …”
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    Walking to your right music: a randomized controlled trial on the novel use of treadmill plus music in Parkinson’s disease
  12. 21252
    “…Finally, transport of these animals to the indoor laboratory and subsequent assessment of their activity rhythms under constant darkness revealed a switch in the timing of activity. …”
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    Day and night in the subterranean: measuring daily activity patterns of subterranean rodents (Ctenomys aff. knighti) using bio-logging
  13. 21253
    “…Contrary to normal ambient temperatures, sleep-wake rhythms were maintained during torpor until body temperature (Tb) of the animals reached 21°C. …”
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    Daily Torpor and Sleep in a Non-human Primate, the Gray Mouse Lemur (Microcebus murinus)
  14. 21254
    “…Of the ∼1,420 proteins that were accurately quantified, 15% (214 proteins) displayed circadian rhythms in abundance in the hippocampus of young mice, while only 1.6% (23 proteins) were rhythmic in middle-aged mice. …”
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    Aging Disrupts the Circadian Patterns of Protein Expression in the Murine Hippocampus
  15. 21255
    por Chen, Yue, Zeng, Qinglu
    Publicado 2020
    “…In this dataset, it was previously shown that aggregate transcripts from cyanophage scaffolds display diurnal transcriptional rhythms with transcript abundances decreasing at night. …”
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    Temporal transcriptional patterns of cyanophage genes suggest synchronized infection of cyanobacteria in the oceans
  16. 21256
    “…Hospital-wide PEA arrests and shockable rhythms both decreased significantly. PEA rhythms significantly decreased in acute care wards and the ED. …”
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    Reduction of in-hospital cardiac arrest with sequential deployment of rapid response team and medical emergency team to the emergency department and acute care wards
  17. 21257
    por Woller, Aurore, Gonze, Didier
    Publicado 2021
    “…Circadian rhythms originate at the cellular level through a transcriptional–translational regulatory network involving a handful of clock genes. …”
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    Circadian Misalignment and Metabolic Disorders: A Story of Twisted Clocks
  18. 21258
    “…Recent work based on behavioral measures revealed an entrainment effect of auditory rhythms on motor rhythms. In this study, we propose a method to compute the neural component of such a process from an electroencephalographic (EEG) signal. …”
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    Neural Entrainment Meets Behavior: The Stability Index as a Neural Outcome Measure of Auditory-Motor Coupling
  19. 21259
    “…The ROSC advantage was significant in females with non-shockable rhythms (OR 1.48, 95% CI 1.24–1.78, p < 0.001) and females of premenopausal age. …”
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    The effect of sex and age on return of spontaneous circulation and survival to hospital discharge in patients with out of hospital cardiac arrest: A retrospective analysis of a Canadian population
  20. 21260
    “…In contrast, flecainide, another Class I anti-arrhythmic, showed no effects on circadian reporter rhythms. Real-time qPCR analysis in fibroblast cells treated with moricizine revealed significant circadian time- and/or treatment-dependent expression changes in core clock genes, consistent with the above period-lengthening effects. …”
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    Clock-Modulating Activities of the Anti-Arrhythmic Drug Moricizine
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