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21561“…Understanding how biological rhythms are generated throughout the body and the reasons for their dysregulation can provide avenues for temporally directed therapeutics. …”
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21562por Winter, Elizabeth M, Kooijman, Sander, Appelman‐Dijkstra, Natasha M, Meijer, Onno C, Rensen, Patrick CN, Schilperoort, Maaike“…Physiological circadian (ie, 24‐hour) rhythms are critical for bone health. Animal studies have shown that genes involved in the intrinsic molecular clock demonstrate potent circadian expression patterns in bone and that genetic disruption of these clock genes results in a disturbed bone structure and quality. …”
Publicado 2021
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21563por Quigg, Mark, Bazil, Carl W., Boly, Melanie, Louis, Erik St, Liu, Judy, Ptacek, Louis, Maganti, Rama, Kalume, Frank, Gluckman, Bruce J., Pathmanathan, Jay, Pavlova, Milena K., Buchanan, Gordon F.“…A multidisciplinary panel of experts discussed these interactions, centered on whether improvements in sleep or circadian rhythms improve decrease seizure frequency. In addition, education about sleep was lacking in among patients, their families, and physicians, and that focus on education was an extremely important “low hanging fruit” to harvest. …”
Publicado 2021
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21564por Georgieva, Ekaterina, Karamalakova, Yanka, Miteva, Radostina, Abrashev, Hristo, Nikolova, Galina“…The use of illicit drugs has negative effects on the cardiovascular system and is one of the causes of serious cardiovascular pathologies, ranging from abnormal heart rhythms to heart attacks and sudden cardiac death. …”
Publicado 2021
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21565por Shen, Jie, Shan, Jianying, Zhong, Lichao, Liang, Boying, Zhang, Dake, Li, Motao, Tang, Hao“…Here based on recent findings, we discussed dietary plant ingredients that can extend longevity by regulation of metabolism, targeting TRP channels, mitophagy, senescence pathways and circadian rhythms. Better understanding of the detailed effects and mechanisms of dietary ingredients on longevity regulation, would be helpful for developing new intervention tools for preventing aging and aging related diseases. …”
Publicado 2022
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21566“…Mechanistic studies elucidating the relationship between radiotherapy, circadian rhythms, and cell cycle, combined with either our “digital” or “biological” chronodata, would help oncologists successfully chronotype individual patients and strategize treatment plans accordingly.…”
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21567“…Epilepsy can be interpreted as altered brain rhythms from overexcitation or insufficient inhibition. …”
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21568por Wyse, Cathy A., Clarke, Ava C., Nordon, Enya A., Murtagh, Collette, Keogh, Alexandra A., Lopez, Lorna M.“…Seasonal rhythms are endogenous timing mechanisms that allow animals living at temperate latitudes to synchronize their physiology to the seasons. …”
Publicado 2022
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21569por Cheng, Phillip (Xin), Grover, Shrey, Wen, Wen, Sankaranarayanan, Shruthi, Davies, Sierra, Fragetta, Justine, Soto, David, Reinhart, Robert M. G.“…Here, we target the early visual cortex with a protocol of noninvasive, high-resolution alternating current stimulation while participants performed a delayed target–probe discrimination task and reveal dissociable mechanisms of mnemonic processing for conscious and unconscious perceptual contents. Entraining β-rhythms in bilateral visual areas preferentially enhanced short-term memory for seen information, whereas α-entrainment in the same region preferentially enhanced short-term memory for unseen information. …”
Publicado 2022
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21570“…This hinders interdisciplinary research and integrative analyses of rhythms across different domains and datasets. In this paper, we review recent developments in cross-disciplinary rhythmicity research, with a focus on the importance of rhythmic analyses in urban planning and biomedical research. …”
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21574por Sarma, Ashapurna, Sharma, Vishal P., Sarkar, Arindam B., Sekar, M. Chandra, Samuel, Karunakar, Geusz, Michael E.“…They act on a wide variety of biological pathways, including those regulating cell division and circadian rhythms. It is known that circadian clocks can modify cancer therapy effectiveness, according to studies aimed at optimizing treatments based on the circadian cycle. …”
Publicado 2016
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21575por El Allali, Khalid, Achaâban, Mohamed R., Piro, Mohammed, Ouassat, Mohammed, Challet, Etienne, Errami, Mohammed, Lakhdar-Ghazal, Nouria, Calas, André, Pévet, Paul“…In mammals, biological rhythms are driven by a master circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. …”
Publicado 2017
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21576por Arguelles-Prieto, Raquel, Bonmati-Carrion, Maria-Angeles, Rol, Maria Angeles, Madrid, Juan Antonio“…Therefore, it becomes necessary to design non-invasive and practical tools to monitor circadian marker rhythms but also its main synchronizer, the light-dark cycle under free-living conditions. …”
Publicado 2019
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21577por Stone, Leland S., Tyson, Terence L., Cravalho, Patrick F., Feick, Nathan H., Flynn‐Evans, Erin E.“…We foresee potential applications of such oculometric biomarkers assisting in the assessment of readiness‐to‐perform higher risk tasks and in the characterization of sub‐clinical neural impairment in the face of a multiplicity of potential risk factors, including disrupted sleep and circadian rhythms.…”
Publicado 2019
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21578por Kolberg, Eirin, Hjetland, Gunnhild Johnsen, Thun, Eirunn, Pallesen, Ståle, Nordhus, Inger Hilde, Husebo, Bettina S., Flo-Groeneboom, Elisabeth“…These may be elicited or aggravated by disrupted circadian rhythms. Bright light treatment (BLT) is a promising non-pharmacological approach to the management of BPSD, but previous research has yielded mixed results. …”
Publicado 2021
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21579por Higashino, Makoto, Hiraoka, Eiji, Kudo, Yoshiko, Hoshina, Yuiko, Kitamura, Koichi, Sakai, Masahiro, Ito, Shinsuke, Fujimoto, Yoshihisa, Hiasa, Yoichi, Hayashi, Koichi, Fujitani, Shigeki, Suzuki, Toshihiko“…Most of the patients manifested non-shockable rhythms (69.1%); survival to hospital discharge rate was markedly lower than that with shockable rhythms (26.8% vs 72.0%, P < .001). …”
Publicado 2021
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21580“…INTRODUCTION: Understanding how environmental interact challenges with genetic predispositions modulate health and wellbeing is an important area of biomedical research. Circadian rhythms play an important role in coordinating the multitude of cellular and tissue processes that organisms use to predict and adapt to regular changes in the environment, and robust circadian rhythms contribute to optimal physiological and behavioral responses to challenge. …”
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