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21881“…[Image: see text] To maintain daily cycles, the circadian clock must tightly regulate the rhythms of thousands of mRNAs and proteins with the correct period, phase, and amplitude to ultimately drive the wide range of rhythmic biological processes. …”
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21882“…Furthermore, recent findings indicate that cellular redox status is coupled not only to canonical circadian gene expression pathways but also to a noncanonical transcript-independent circadian clock. The redox rhythms observed in peroxiredoxins in the absence of canonical clock mechanisms may hint at the nature of this new and hitherto unknown aspect of circadian timekeeping.…”
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21883“…In the first one distinct nonlinear oscillators representing the brain rhythms involved are coupled actively (bidirectionally), whereas in the second one the oscillators are coupled unidirectionally and thus the driving between them is passive. …”
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21884“…An all-out effort exceeding the magnitude of the Human Genome Project is of essence to construct just mammalian transcriptomes in multiple contexts including embryonic development, circadian and seasonal rhythms, defined life-span stages, pathological conditions and anatomy-driven tissue/organ/cell types.…”
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21885“…This drumming differs from most beating episodes reported in this species by its unusual duration, the lack of any obvious context, and rhythmical properties that include long-lasting and dynamically changing rhythms, but also evenness and leisureliness. This performance is probably the first evidence that our capacity to drum is shared with our closest relatives.…”
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21886por Furutani, Akiko, Ikeda, Yuko, Itokawa, Misa, Nagahama, Hiroki, Ohtsu, Teiji, Furutani, Naoki, Kamagata, Mayo, Yang, Zhi-Hong, Hirasawa, Akira, Tahara, Yu, Shibata, Shigenobu“…Tuna oil (high DHA/EPA), menhaden oil (standard), and DHA/EPA dissolved in soybean oil increased insulin secretion and facilitated RF-induced phase shifts of the liver clock as represented by the bioluminescence rhythms of PER2::LUCIFERASE knock-in mice. In this model, insulin depletion blocked the effect of tuna oil and fish oil had no effect on mice deficient for GPR120, a polyunsaturated fatty acid receptor. …”
Publicado 2015
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21887“…Workers’ fatigue is a significant problem in modern industry, largely because of high demand jobs, long duty periods, disruption of circadian rhythms, and accumulative sleep debt that are common in many industries. …”
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21888“…Moreover, in some patients these fluctuations exhibit some periodic temporal structure which can be attributed, to a large extent, to daily rhythms. Relevant aspects of the epileptic process, particularly possible pre-seizure alterations, contribute marginally to the observed long-term fluctuations. …”
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21889por Sotero, Roberto C.“…PAC is a diverse phenomenon, having been experimentally detected in at least ten combinations of rhythms: delta-theta, delta-alpha, delta-beta, delta-gamma, theta-alpha, theta-beta, theta-gamma, alpha-beta, alpha-gamma, and beta-gamma. …”
Publicado 2015
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21890por Rivnay, Jonathan, Leleux, Pierre, Ferro, Marc, Sessolo, Michele, Williamson, Adam, Koutsouras, Dimitrios A., Khodagholy, Dion, Ramuz, Marc, Strakosas, Xenofon, Owens, Roisin M., Benar, Christian, Badier, Jean-Michel, Bernard, Christophe, Malliaras, George G.“…This results in a dependence of the transconductance on channel thickness, a new degree of freedom that we exploit to demonstrate high-quality recordings of human brain rhythms. Our results bring to the forefront a transistor class in which performance can be tuned independently of device footprint and provide guidelines for the design of materials that will lead to state-of-the-art transistor performance.…”
Publicado 2015
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21891“…Here, we use independent component analysis to derive information theoretically optimal, non-redundant codes (filter populations) for seven typologically distinct languages (Dutch, English, Japanese, Marathi, Polish, Spanish and Turkish) and relate the statistical properties of these filter populations to documented differences in the speech rhythms (Analysis 1) and consonant inventories (Analysis 2) of these languages. …”
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21892por Lane, Jacqueline M., Vlasac, Irma, Anderson, Simon G., Kyle, Simon D., Dixon, William G., Bechtold, David A., Gill, Shubhroz, Little, Max A., Luik, Annemarie, Loudon, Andrew, Emsley, Richard, Scheer, Frank A. J. L., Lawlor, Deborah A., Redline, Susan, Ray, David W., Rutter, Martin K., Saxena, Richa“…We identify 12 new genetic loci that implicate known components of the circadian clock machinery and point to previously unstudied genetic variants and candidate genes that might modulate core circadian rhythms or light-sensing pathways. Pathway analyses highlight central nervous and ocular systems and fear-response-related processes. …”
Publicado 2016
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21893“…The amplitudes of the cortical current dipoles were estimated by applying a variant of synthetic aperture magnetometry to magnetoencephalographic (MEG) recordings of subjects tapping to metric auditory rhythms of drum beats. Brief amplitude undulations were detected in the currents by template matching at a rate of 2–3 per second. …”
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21894por Colombi, Ilaria, Tinarelli, Federico, Pasquale, Valentina, Tucci, Valter, Chiappalone, Michela“…Supporting the electrophysiological analysis results, gene expressions of targeted genes showed the activation of specific markers involved in sleep-wake rhythms. Our results demonstrate that the Carbachol treatment induces desynchronization of neuronal activity, altering sleep-like properties in an in vitro model.…”
Publicado 2016
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21895“…The inherent heterogeneity in the properties of cellular clocks observed under constant conditions is corrected under light-dark cycles to coordinate the daily rhythms of the plant body. These findings provide a novel perspective of spatiotemporal architectures in the plant circadian system.…”
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21896por Gotic, Ivana, Omidi, Saeed, Fleury-Olela, Fabienne, Molina, Nacho, Naef, Felix, Schibler, Ueli“…Despite the small differences between minimal and maximal values, body temperature rhythms can drive robust cycles in gene expression in cultured cells and, likely, animals. …”
Publicado 2016
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21897por Krishnan, Giri P, Chauvette, Sylvain, Shamie, Isaac, Soltani, Sara, Timofeev, Igor, Cash, Sydney S, Halgren, Eric, Bazhenov, Maxim“…Overall, our study revealed the critical intrinsic and synaptic mechanisms through which different neuromodulators acting in combination result in characteristic brain EEG rhythms and transitions between sleep stages. DOI: http://dx.doi.org/10.7554/eLife.18607.001…”
Publicado 2016
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21898por Meng, Jianjun, Zhang, Shuying, Bekyo, Angeliki, Olsoe, Jaron, Baxter, Bryan, He, Bin“…Subjects were able to effectively control reaching of the robotic arm through modulation of their brain rhythms within the span of only a few training sessions and maintained the ability to control the robotic arm over multiple months. …”
Publicado 2016
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21899“…We find that the expression of PIF4 target genes show circadian rhythms of thermosensitivity, with minimum responsiveness in the evening when TOC1 level is high. …”
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21900“…In contrast, when two sets of synchronized beating cells came into contact, those two sets synchronized without any observable interruptions to their rhythms. The results indicate that the synchronization process of cardiac myocytes may be dependent on the community size and network pattern of these cells.…”
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