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  1. 22321
    “…Various physiological and behavioral processes exhibit circadian rhythmicity. These rhythms are usually maintained by negative feedback loops of core clock genes, namely, CLOCK, BMAL, PER, and CRY. …”
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    A Molecular Clock Regulates Angiopoietin-Like Protein 2 Expression
  2. 22322
    “…Circadian TPL (cTPL) was found to be Cry clock gene dependent, confirming the essential role of Cry genes in circadian rhythms. In contrast, preliminary results have shown that cTPL is independent of Per genes. …”
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    Circadian clocks and memory: time-place learning
  3. 22323
    “…In mammals, a network of circadian clocks regulates 24-h rhythms of behavior and physiology. Circadian disruption promotes obesity and the development of obesity-associated disorders, but it remains unclear to which extent peripheral tissue clocks contribute to this effect. …”
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    Circadian Regulation of Lipid Mobilization in White Adipose Tissues
  4. 22324
    “…We now show that modulation of CK1 function lengthens circadian rhythms in Ostreococcus tauri , a unicellular marine algal species at the base of the green lineage, separated from humans by ~1.5 billion years of evolution. …”
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    Functional Analysis of Casein Kinase 1 in a Minimal Circadian System
  5. 22325
    por Bayonas, Alberto Carmona
    Publicado 2011
    “…The postsurgical patterns of progression include unexpected features such as distant interactions and variable rhythms. The underlying evidence can be summarized as follows: (1) the resection of the primary tumor is able to accelerate the evolution of micrometastasis in early stages, and (2) the outcome is transiently opposed in advanced tumors. …”
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    An Evolutionary Explanation for the Perturbation of the Dynamics of Metastatic Tumors Induced by Surgery and Acute Inflammation
  6. 22326
    “…Gap junctions, also referred to as electrical synapses, are expressed along the entire central nervous system and are important in mediating various brain rhythms in both normal and pathological states. These connections can form between the dendritic trees of individual cells. …”
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    Gap Junctions, Dendrites and Resonances: A Recipe for Tuning Network Dynamics
  7. 22327
    “…Here we show autonomous circadian rhythms in mouse tendon and primary human tenocytes, controlled by an intrinsic molecular circadian clock. …”
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    Gremlin-2 is a BMP antagonist that is regulated by the circadian clock
  8. 22328
    “…Cyanobacterial genomes showed especially strong periodic signals and, on the other hand, DNA supercoiling and supercoiling-dependent transcription are highly dynamic and underlie circadian rhythms of these phototrophic bacteria. Focusing on this phylum and dinucleotides, we find that a minimal motif of AT-tracts (AT2) yields the strongest signal. …”
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    The structural code of cyanobacterial genomes
  9. 22329
    “…The mammalian circadian clock is driven by a transcriptional–translational feedback loop, which produces robust 24-hr rhythms. Proper oscillation of the clock depends on the complex formation and periodic turnover of the Period and Cryptochrome proteins, which together inhibit their own transcriptional activator complex, CLOCK-BMAL1. …”
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    Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex
  10. 22330
    “…Previous studies have shown that retinal melatonin plays an important role in the regulation of retinal daily and circadian rhythms. Melatonin exerts its influence by binding to G-protein coupled receptors named melatonin receptor type 1 and type 2 and both receptors are present in the mouse retina. …”
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    Melatonin Signaling Modulates Clock Genes Expression in the Mouse Retina
  11. 22331
    “…Circadian clocks allow organisms to orchestrate the daily rhythms in physiology and behaviors, and disruption of circadian rhythmicity can profoundly affect fitness. …”
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    An intensity ratio of interlocking loops determines circadian period length
  12. 22332
    “…We identified studies describing effects of shift work in terms of sleep, adaptation and re-adaptation of circadian rhythms, health outcomes, safety and accidents, family and social life, and work perceptions. …”
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    Effects of Shift and Night Work in the Offshore Petroleum Industry: A Systematic Review
  13. 22333
    “…Positive effects seems to be achieved by the alternation of fast, slow rhythms and pauses even in pediatric age.…”
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    Music Benefits on Postoperative Distress and Pain in Pediatric Day Care Surgery
  14. 22334
    “…Unlike GSH, its precursors and products of catabolism, methionine, cysteine and cysteinyl-glycine, were not rhythmic in young or old flies, while rhythms of the glutathione oxidation product, GSSG, were detectable. …”
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    Aging alters circadian regulation of redox in Drosophila
  15. 22335
    “…Neurospora crassa has been utilized as a model organism for studying biological, regulatory, and circadian rhythms for over 50 years. These circadian cycles are driven at the molecular level by gene transcription events to prepare for environmental changes. …”
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    Suppressing the Neurospora crassa circadian clock while maintaining light responsiveness in continuous stirred tank reactors
  16. 22336
    “…Circadian rhythms govern all biological functions. Circadian misalignment has a major impact on health. …”
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    Chronotypes in Patients with Epilepsy: Does the Type of Epilepsy Make a Difference?
  17. 22337
    “…We propose that internal desynchronization or bifurcation of SCN circadian rhythms may underlie rapid-cycling manic-depressive disorders and perhaps most mania.  …”
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    Photoperiodic and circadian bifurcation theories of depression and mania
  18. 22338
    “…Daily rhythms in Drosophila under semi-natural conditions (or SN) have received much recent attention. …”
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    dTRPA1 Modulates Afternoon Peak of Activity of Fruit Flies Drosophila melanogaster
  19. 22339
    “…Artificial lighting can alter individual behaviour, with often drastic and potentially negative effects on biological rhythms, daily activity and reproduction. Whether this is caused by a disruption of sleep, an important widespread behaviour enabling animals to recover from daily stress, is unclear. …”
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    Light pollution disrupts sleep in free-living animals
  20. 22340
    “…Sleep phase delays can affect an individual’s circadian rhythms on the following day and cause daytime sleepiness and/or poor performance. …”
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    Monitoring of Weekly Sleep Pattern Variations at Home with a Contactless Biomotion Sensor
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