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  1. 22681
    “…Questions targeted the conditions of quarantine, sleep related behaviours and exposure to factors known to affect sleep and circadian rhythms (light exposure and sport). RESULTS: In all, 1777 participants were included: 77% women and 72% aged 25–54 years. …”
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    Les effets de confinement SARS-CoV-2 sur le sommeil : enquête en ligne au cours de la quatrième semaine de confinement
  2. 22682
    “…Bradycardia and ventricular escape rhythms arise from impaired myocardial automaticity and conductivity due to sodium and potassium channel blockade. …”
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    Chloroquine, hydroxychloroquine and COVID-19
  3. 22683
    “…Circadian rhythms are essential for controlling the cell cycle, cellular proliferation, and apoptosis, and hence are tightly linked to cell fate. …”
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    Oncogenic and Circadian Effects of Small Molecules Directly and Indirectly Targeting the Core Circadian Clock
  4. 22684
    “…Exposure to artificial bright light in the late evening and early night, common in modern society, triggers phase delay of circadian rhythms, contributing to delayed sleep phase syndrome and seasonal affective disorder. …”
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    Daily and Seasonal Variation in Light Exposure among the Old Order Amish
  5. 22685
    por Iyer, Ashvin, Holaska, James M.
    Publicado 2020
    “…Mutations in the gene encoding emerin (EMD) cause Emery–Dreifuss muscular dystrophy (EDMD1), an inherited disorder characterized by progressive skeletal muscle wasting, irregular heart rhythms and contractures of major tendons. The skeletal muscle defects seen in EDMD are caused by failure of muscle stem cells to differentiate and regenerate the damaged muscle. …”
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    EDMD-Causing Emerin Mutant Myogenic Progenitors Exhibit Impaired Differentiation Using Similar Mechanisms
  6. 22686
    por Lee, Hojun, Jo, Kyoung-nam, Hyun, Sangmin
    Publicado 2020
    “…Although the responses of North Atlantic Deep Water (NADW) is deeply connected to orbital rhythms, those under different tectonic and atmospheric boundary conditions remain unknown. …”
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    Opposite response modes of NADW dynamics to obliquity forcing during the late Paleogene
  7. 22687
    por Lu, Renbin, Dong, Yufan, Li, Jia-Da
    Publicado 2020
    “…Depletion of necdin or SGT1/HSP90 leads to degradation of BMAL1 through the ubiquitin–proteasome system, resulting in alterations in both clock gene expression and circadian rhythms. Taken together, our data identify the PWS-associated protein necdin as a novel regulator of the circadian clock, and further emphasize the critical roles of chaperone machinery in circadian clock regulation.…”
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    Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery
  8. 22688
    por Lee, Sun-Kyung, Ahnn, Joohong
    Publicado 2020
    “…Novel functions of RCANs have recently emerged, indicating involvement in mitochondria homeostasis, RNA binding, circadian rhythms, obesity, and thermogenesis, some of which are calcineurin-independent. …”
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    Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region
  9. 22689
    “…This includes discussion of dopamine neurons’ morphologies, potential identities, and biophysical properties along with their contributions to circadian rhythms and stimulus-driven synthesis, activation, and release of dopamine. …”
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    Illuminating and Sniffing Out the Neuromodulatory Roles of Dopamine in the Retina and Olfactory Bulb
  10. 22690
    “…While chronic LAN disturbs daily rhythms in these parameters, experiments using short‐term LAN exposure also have shown acute negative effects in metabolically active peripheral tissues. …”
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    Metabolic Implications of Exposure to Light at Night: Lessons from Animal and Human Studies
  11. 22691
    “…However, that is not so in the case of polycystic ovary syndrome (PCOS), in which case the central mechanism responsible for entraining hormonal and metabolic rhythms during the menstrual cycle is notably disrupted. …”
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    In Search of New Therapeutics—Molecular Aspects of the PCOS Pathophysiology: Genetics, Hormones, Metabolism and Beyond
  12. 22692
    “…It can disrupt circadian rhythms, interfere with sleep, and participate in the progress of civilisation diseases. …”
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    Impact of Dim Light at Night on Urinary 6-Sulphatoxymelatonin Concentrations and Sleep in Healthy Humans
  13. 22693
    “…While people with excessive exposure to noise are frequently the population with a lifestyle of irregular circadian rhythms, the effects of circadian dysregulation on the auditory system are still little known. …”
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    Constant Light Dysregulates Cochlear Circadian Clock and Exacerbates Noise-Induced Hearing Loss
  14. 22694
    “…New applications of the PPG are also emerging, such as to detect irregular heart rhythms, track infectious diseases, and monitor blood pressure. …”
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    Acquiring Wearable Photoplethysmography Data in Daily Life: The PPG Diary Pilot Study (†)
  15. 22695
    “…We classified trials off-line into positive- and negative-phase classes according to the mu and beta rhythms. We calculated differences in the global mean-field amplitude (GMFA) and compared the cortical spreading of the TMS-evoked activity between the two classes. …”
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    Local brain-state dependency of effective connectivity: a pilot TMS–EEG study
  16. 22696
    “…The aim of this surveillance program was to evaluate the efficacy of melatonin (Melaxen(®)) in patients with TTH and disruption of circadian rhythms in real-world practice. METHODS: Sixty-one patients with chronic TTH were enrolled. …”
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    Safety and Efficacy of Melatonin in Chronic Tension-Type Headache: A Post-Marketing Real-World Surveillance Program
  17. 22697
    “…Genes of the F-box family play specific roles in protein degradation by post-translational modification in several biological processes, including flowering, the regulation of circadian rhythms, photomorphogenesis, seed development, leaf senescence, and hormone signaling. …”
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    F-Box Genes in the Wheat Genome and Expression Profiling in Wheat at Different Developmental Stages
  18. 22698
    “…During locomotion, theta and gamma rhythms are essential to ensure timely communication between brain structures. …”
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    Adaptive modulation of brain hemodynamics across stereotyped running episodes
  19. 22699
    “…A distinct 12-hour clock exists in addition to the 24-hour circadian clock to coordinate metabolic and stress rhythms. Here, we show that liver-specific ablation of X-box binding protein 1 (XBP1) disrupts the hepatic 12-hour clock and promotes spontaneous non-alcoholic fatty liver disease (NAFLD). …”
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    XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis
  20. 22700
    “…Part of a symposium sponsored by the Sleep, Circadian Rhythms and Aging Interest Group.…”
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    Personality and Insomnia Symptoms in Older Adults: The Baltimore Longitudinal Study of Aging
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