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  1. 23201
    “…Most of mammalian physiology is under the control of biological rhythms, including the endocrine system with time-varying hormone secretion. …”
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    Diurnal fluctuations in steroid hormones tied to variation in intrinsic functional connectivity in a densely sampled male
  2. 23202
    “…The hypoactivity episodes, which lasted for several weeks, were accompanied by abnormal circadian rhythms and a marked decrease in wheel running, a spontaneous behavior associated with motivation and reward systems. …”
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    GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice
  3. 23203
    “…Several studies have confirmed that the circadian rhythms induce multiple malignancies developing. We utilized multi-omics analysis to demonstrate the crosstalk between circadian clock genes and tumor microenvironment in HNSCC. …”
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    Identify and validate circadian regulators as potential prognostic markers and immune infiltrates in head and neck squamous cell carcinoma
  4. 23204
    “…In humans, LCSD reduces the release of norepinephrine, normalizes the QT interval, and decreases the likelihood of life-threatening heart rhythms. The procedure does not impair heart rate or cardiac function due to the compensatory effects of the right cardiac sympathetic nerves. …”
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    Unlocking the Potential of Left Cardiac Sympathetic Denervation: A Scoping Review of a Promising Approach for Long QT Syndrome
  5. 23205
    “…Seven days after starting treatment with corticosteroids, she presented maniform symptoms (psychomotor restlessness, expansive mood, dysphoria, megalomanic delusions, alteration of biological rhythms with decreased need for sleep and risk behaviors), and she was admitted in a psychiatric hospitalization unit. …”
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    Causal relationship between the administration of high-dose corticosteroids and the appearance of maniform-type psychopathology
  6. 23206
    “…Therefore, it could be relevant when collecting research data on the non-image forming (NIF) effects of light on circadian rhythms and sleep. In fact, studies conducted only in winter may result in more pronounced NIF effects than in summer. …”
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    Seasonal Variation in the Responsiveness of the Melanopsin System to Evening Light: Why We Should Report Season When Collecting Data in Human Sleep and Circadian Studies
  7. 23207
    “…INTRODUCTION: Transcranial alternating current stimulation (tACS) can regulate brain functions by modulating endogenous brain rhythms. Theta-band neural oscillations are associated with memory function. …”
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    Neuromodulatory effects of high-definition theta transcranial alternating current stimulation on the parietal cortex: a pilot study of healthy males
  8. 23208
    “…RESULTS: While most of the components of published paediatric life support algorithms of Asian countries are similar, there are notable variations in terms of age criteria for recommended use of adult basic life support algorithms in the paediatric population less than 18 years old, recommended paediatric chest compression depth targets, ventilation rates post-advanced airway intra-arrest, and first defibrillation dose for shockable rhythms in paediatric cardiac arrest. CONCLUSION: This was an overview and mapping of published Asian paediatric resuscitation algorithms. …”
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    Comparison of paediatric basic life support guidelines endorsed by member councils of Resuscitation Council of Asia
  9. 23209
    “…Period2 (Per2) is an essential component of the mammalian clock mechanism and robust circadian expression of Per2 is essential for the maintenance of circadian rhythms. Although recent studies have shown that the circadian E2 enhancer (a non-canonical E-box) accounts for most of the circadian transcriptional drive of mPer2, little is known about the other cis-elements of mPer2 oscillatory transcription. …”
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    A novel E4BP4 element drives circadian expression of mPeriod2
  10. 23210
    “…The most peculiar feature of hippocampal sleep is the increased synchronization of the EEG rhythms during REM periods. This state of resonance may have a supportive role for the processing/consolidation of memory.…”
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    Sleep in the Human Hippocampus: A Stereo-EEG Study
  11. 23211
    “…Of clock or clock-regulated genes, the synchronized, global cycling pattern of Fabp7 expression is unique and implicates glial cells in the response or modulation of activity and/or circadian rhythms.…”
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    Brain Fatty Acid Binding Protein (Fabp7) Is Diurnally Regulated in Astrocytes and Hippocampal Granule Cell Precursors in Adult Rodent Brain
  12. 23212
    “…METHODOLOGY/PRINCIPAL FINDINGS: CKIε, but not CKIα, binds to and phosphorylates two proteins: Period, a transcriptional regulator of the circadian rhythms pathway, and Disheveled, an activator of the planar cell polarity pathway. …”
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    Interactions between Casein Kinase Iε (CKIε) and Two Substrates from Disparate Signaling Pathways Reveal Mechanisms for Substrate-Kinase Specificity
  13. 23213
    “…Circadian transcription factors then drive daily rhythms in the expression of clock-controlled output genes, for example genes encoding enzymes and regulators of cellular metabolism. …”
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    REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis
  14. 23214
    “…Anti-cancer chronotherapy, in which treatments are administered at a particular time each day, aims at exploiting these biological rhythms to reduce toxicity and improve efficacy of the treatment. …”
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    Tumor Growth Rate Determines the Timing of Optimal Chronomodulated Treatment Schedules
  15. 23215
    “…The applicability of our method is demonstrated by the analysis of the underlying model for circadian rhythms in Drosophila. CONCLUSIONS: Building ASTD is a useful means to convert a hybrid model dealing with discrete, continuous and more complicated events to finite time-dependent states. …”
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    Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram
  16. 23216
    “…Additionally, the use of an antisense oligonucleotide to knock down miR-122 in vivo resulted in significant up-regulation of both Nocturnin mRNA and protein expression in mouse liver during the night, resulting in Nocturnin rhythms with increased amplitude. Together, these data demonstrate that the normal rhythmic profile of Nocturnin expression in liver is shaped in part by miR-122. …”
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    MicroRNA-122 Modulates the Rhythmic Expression Profile of the Circadian Deadenylase Nocturnin in Mouse Liver
  17. 23217
    por Portolés, Sergi, Más, Paloma
    Publicado 2010
    “…Circadian rhythms are daily biological oscillations driven by an endogenous mechanism known as circadian clock. …”
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    The Functional Interplay between Protein Kinase CK2 and CCA1 Transcriptional Activity Is Essential for Clock Temperature Compensation in Arabidopsis
  18. 23218
    “…BACKGROUND: Working mostly at night has been suggested to be associated with upset of chronobiological rhythms and high blood pressure, but the evidence from epidemiological studies is weak. …”
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    Shift Work Is Not Associated with High Blood Pressure or Prevalence of Hypertension
  19. 23219
    “…Despite growing acceptance that biological rhythms profoundly influence energy homeostasis, little is known regarding how the timing of nutrient ingestion influences development of common metabolic diseases. …”
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    Time-of-Day-Dependent Dietary Fat Consumption Influences Multiple Cardiometabolic Syndrome Parameters in Mice
  20. 23220
    “…Lesion and transplantation studies in the cockroach, Leucophaea maderae, have located its bilaterally symmetric circadian pacemakers necessary for driving circadian locomotor activity rhythms to the accessory medulla of the optic lobes. …”
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    Circadian pacemaker coupling by multi-peptidergic neurons in the cockroach Leucophaea maderae
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