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  1. 23901
    “…Melatonin primarily regulates circadian rhythms but also exerts anti-inflammatory, anti-depressant, antioxidant and anti-tumor activities. …”
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    Metabolic Anti-Cancer Effects of Melatonin: Clinically Relevant Prospects
  2. 23902
    “…Despite other cardiac examinations performed on these patients showing normal results, in combination with a strict inclusion criterion, this study showed that 28% of all subjects had pathological resting 12-lead ECGs at rest and 35% had pathological heart rhythms when assessed by 24-h Holter ECG. At follow-up, 21% of females and 43% of males had presented with ECG abnormalities, and 30% of females and 36% of males had cardiovascular disease. …”
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    Are ECG changes in heart-healthy individuals of various ages related to cardiac disease 20 years later?
  3. 23903
    “…This fact could be attributed to circadian rhythms, having a strong influence on HRV values. …”
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    Cardiopulmonary coupling indices to assess weaning readiness from mechanical ventilation
  4. 23904
    “…We then examine the potential role that extracellular H(+) released by glia might play in regulating synaptic transmission within the vertebrate retina, and then expand the focus to discuss potential roles in spreading depression, migraine, epilepsy, and alterations in brain rhythms, and suggest that alterations in extracellular H(+) may be a unifying feature linking these disparate phenomena.…”
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    Review and Hypothesis: A Potential Common Link Between Glial Cells, Calcium Changes, Modulation of Synaptic Transmission, Spreading Depression, Migraine, and Epilepsy—H(+)
  5. 23905
    “…However, as a modulator of endogenous physiological circadian rhythms, the effects of melatonin on poststroke sleep disorders remain unclear. …”
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    Melatonin supplementation in the subacute phase after ischemia alleviates postischemic sleep disturbances in rats
  6. 23906
    “…Chronotherapy that consists in adapting drug administration to the patient’s circadian rhythms may be improved by such approach. Recent clinical studies demonstrated large variability in patients’ circadian coordination and optimal drug timing. …”
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    Model learning to identify systemic regulators of the peripheral circadian clock
  7. 23907
    “…(Ser358Leu) mutation has been shown to alter intercalated disc protein function and disturb beating rhythms. In the cochlea, the p.(Arg372Ter) mutation has been shown to disrupt connexin-linked function in glia-like supporting cells (GLSs), which maintain inner ear homeostasis for hearing. …”
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    A Deafness Associated Protein TMEM43 Interacts with KCNK3 (TASK-1) Two-pore Domain K(+) (K2P) Channel in the Cochlea
  8. 23908
    “…Melatonin is a neurohormone synthesized in the pineal gland and is involved in circadian rhythms in mammals, as well as other physiological functions. …”
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    Melatonin attenuates morphine‐induced conditioned place preference in Wistar rats
  9. 23909
    “…Introduction: Melatonin, an endogenous neurohormone, modulates the biological circadian rhythms of vertebrates. It functions have been reported in previous stomatological studies as anti-inflammation, antioxidant, osseointegration of dental implants and stimulation to dental pulp stem cells differentiation, but its role in ameloblastic differentiation and mineralization has been rarely studied. …”
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    Melatonin-Medicated Neural JNK3 Up-Regulation Promotes Ameloblastic Mineralization
  10. 23910
    “…The retina of vertebrates is responsible for capturing light through visual (cones and rods) and non-visual photoreceptors (intrinsically photosensitive retinal ganglion cells and horizontal cells) triggering a number of essential activities associated to image- and non-image forming functions (photic entrainment of daily rhythms, pupillary light reflexes, pineal melatonin inhibition, among others). …”
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    The Intrinsic Blue Light Responses of Avian Müller Glial Cells Imply Calcium Release from Internal Stores
  11. 23911
    “…BACKGROUND: Circadian rhythms coordinate multiple biological processes, and time of eating is an important entrainer of peripheral circadian clocks, including those in the gastrointestinal tract and liver. …”
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    Psychometric Testing of a Food Timing Questionnaire and Food Timing Screener
  12. 23912
    “…The findings increase our understanding of the crosstalk between skin clock and acne and suggest targeting circadian rhythms as a promising approach for management of acne.…”
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    BMAL1 regulates Propionibacterium acnes-induced skin inflammation via REV-ERBα in mice
  13. 23913
    “…Detailed verification of the model showed that predictions were made based on disrupted sleep rhythms, mild physical activity duration, alcohol use, and medical examination data on disrupted eating habits as risk factors. …”
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    Predictive Modeling of Mental Illness Onset Using Wearable Devices and Medical Examination Data: Machine Learning Approach
  14. 23914
    por Ye, Xiaohong, Huang, Yuanqi, Lu, Qiang
    Publicado 2022
    “…We demonstrated the feasibility and effectiveness of the XGBoost-based fusion model to classify 12-lead electrocardiogram records into nine common heart rhythms. These findings may have clinical importance for the early diagnosis of arrhythmia and incite further research. …”
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    Automatic Multichannel Electrocardiogram Record Classification Using XGBoost Fusion Model
  15. 23915
    “…We prospectively evaluated SuperMap during mapping and ablation of atrial tachycardias (ATs) and paced rhythms and compared to conventional high-density contact mapping. …”
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    Clinical utility of non-contact charge density ‘SuperMap’ algorithm for the mapping and ablation of organized atrial arrhythmias
  16. 23916
    “…Sleep manifests itself by the spontaneous emergence of characteristic oscillatory rhythms, which often time-lock and are implicated in memory formation. …”
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    Cross-Frequency Slow Oscillation–Spindle Coupling in a Biophysically Realistic Thalamocortical Neural Mass Model
  17. 23917
    “…The findings indicated that although CSL referees showed little difference in physical performance when officiating matches of three competitive levels and two halves, distinct rhythms of competitions determined that they needed to adjust running strategies to maintain proper distance to the ball. …”
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    Impact of Match Type and Match Halves on Referees’ Physical Performance and Decision-Making Distance in Chinese Football Super League
  18. 23918
    “…BACKGROUND: Electroencephalography (EEG) studies in Autism Spectrum Disorder (ASD) have investigated spectral power, coherence of EEG rhythms and asymmetry of the bands across various brain regions. …”
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    Investigating EEG Delta Band Differences in Preschool Children with Autism during Awake and Sleep Stages
  19. 23919
    “…The questionnaire included items on sociodemographic variables as well as the Japanese version of the Biological Rhythms Interview of Assessment in Neuropsychiatry self-report (J-BRIAN-SR), which assesses the risk of DSWPD, sleep behaviors and possibly related lifestyle variables, productivity loss [WHO Health and Work Performance Questionnaire (HPQ)], and health-related quality of life (HRQOL). …”
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    Prevalence and Factors Associated With the Risk of Delayed Sleep-Wake Phase Disorder in Japanese Youth
  20. 23920
    por Coutinho-da-Silva, Mikelly Santos, Sucupira, Pedro Henrique Ferreira, Bicalho, Kelly Alves, Campi-Azevedo, Ana Carolina, Brito-de-Sousa, Joaquim Pedro, Peruhype-Magalhães, Vanessa, Rios, Maria, Teixeira-Carvalho, Andréa, Coelho-dos-Reis, Jordana Grazziela Alves, Antonelli, Lis Ribeiro do Valle, de Rezende, Vitor Bortolo, de Melo, Fernanda Ludolf Ribeiro, Garcia, Cristiana Couto, Silva-Andrade, Jesuanne Carla, da Costa-Rocha, Ismael Artur, Bastos, Michele de Souza, da Rocha, Lucia Alves, Silva, Valderjane Aprigio, Ferreira, Ewerton da Silva, Marinho, Eveny Perlize Melo, Costa, Allyson Guimarães, Gomes, Matheus de Souza, Amaral, Laurence Rodrigues, Furtado, Erilene Cristina da Silva, da Silva, Eliana Vieira Pinto, Ramos, Bruna Alves, dos Santos, Éder Barros, Freitas, Maria Nazaré Oliveira, Vasconcelos, Pedro Fernando da Costa, Martins-Filho, Olindo Assis, Araújo, Márcio Sobreira Silva, Ferreira, Milene Silveira, Martins, Livia Carício
    Publicado 2022
    “…Overall, our results provided a comprehensive overview of the immune response elicited by DENV infection, revealing that infection with distinct DENV serotypes causes distinct profiles, rhythms, and dynamic network connectivity of soluble mediators. …”
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    Serum Soluble Mediator Profiles and Networks During Acute Infection With Distinct DENV Serotypes
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