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281“…The RIBE is elicited by agents and factors released by IR-hit cells. …”
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282por Wu, Wenqing, Nie, Lili, Yu, K. N., Wu, Lijun, Kong, Peizhong, Bao, Lingzhi, Chen, Guodong, Yang, Haoran, Han, Wei“…During radiotherapy procedures, radiation-induced bystander effect (RIBE) can potentially lead to genetic hazards to normal tissues surrounding the targeted regions. …”
Publicado 2016
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283por Hara, Daiki, Tao, Wensi, Schmidt, Ryder M., Yang, Yu-Ping, Daunert, Sylvia, Dogan, Nesrin, Ford, John Chetley, Pollack, Alan, Shi, Junwei“…Herein, we investigated the effects of active-targeting GNPs on the radiation-induced bystander effect (RIBE) in prostate cancer cells. The impact of GNPs on the RIBE presents implications for secondary cancers or spatially fractionated radiotherapy treatments. …”
Publicado 2022
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284“…BACKGROUND: The radiation-induced “bystander effect” (RIBE) was shown to occur in a number of experimental systems both in vitro and in vivo as a result of exposure to ionizing radiation (IR). …”
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285por Kirolikar, Saurabh, Prasannan, Preeti, Raghuram, Gorantla V., Pancholi, Namrata, Saha, Tannishtha, Tidke, Pritishkumar, Chaudhari, Pradip, Shaikh, Alfina, Rane, Bhagyeshri, Pandey, Richa, Wani, Harshada, Khare, Naveen K., Siddiqui, Sophiya, D’souza, Jenevieve, Prasad, Ratnam, Shinde, Sushma, Parab, Sailee, Nair, Naveen K., Pal, Kavita, Mittra, Indraneel“…Radiation-induced bystander effect (RIBE) is a poorly understood phenomenon wherein non-targeted cells exhibit effects of radiation. …”
Publicado 2018
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286por Li, Lu, Wang, Lu, Prise, Kevin M., Yu, K.N ., Chen, Guodong, Chen, Lianyun, Mei, Yide, Han, Wei“…Cytoplasm is an important target for the radiation-induced bystander effect (RIBE). In the present work, the critical role of protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway in the generation of RIBE signaling after X-ray irradiation and the rapid phosphorylation of Akt and mTOR was observed in the cytoplasm of irradiated human lung adenocarcinoma epithelial (A549) cells. …”
Publicado 2017
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287por Song, Man, Wang, Yu, Shang, Zeng-Fu, Liu, Xiao-Dan, Xie, Da-Fei, Wang, Qi, Guan, Hua, Zhou, Ping-Kun“…Radiation-induced bystander effect (RIBE) describes a set of biological effects in non-targeted cells that receive bystander signals from the irradiated cells. …”
Publicado 2016
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288por Ariyoshi, Kentaro, Miura, Tomisato, Kasai, Kosuke, Fujishima, Yohei, Nakata, Akifumi, Yoshida, Mitsuaki“…Exosome-like vesicles (ELV) are involved in mediating radiation-induced bystander effect (RIBE). Here, we used ELV from control cell conditioned medium (CCCM) and from 4 Gy of X-ray irradiated cell conditioned medium (ICCM), which has been used to culture normal human fibroblast cells to examine the possibility of ELV mediating RIBE signals. …”
Publicado 2019
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289por Kulcenty, Katarzyna, Piotrowski, Igor, Rucinski, Marcin, Wroblewska, Joanna Patrycja, Jopek, Karol, Murawa, Dawid, Suchorska, Wiktoria Maria“…We hypothesized that SWF obtained from patients after BCS and IORT would induce a radiobiological response (due to RIBE) in unirradiated cells, thereby modifying their phenotype. …”
Publicado 2020
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290por Xie, Yuexia, Ye, Shuang, Zhang, Jianghong, He, Mingyuan, Dong, Chen, Tu, Wenzhi, Liu, Peifeng, Shao, Chunlin“…Radiation-induced bystander effect (RIBE) has important implications for secondary cancer risk assessment during cancer radiotherapy, but the defense and self-protective mechanisms of bystander normal cells are still largely unclear. …”
Publicado 2016
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291por Ilyas, AbdulMojeed O., Alam, Md Kowsar, Musah, Jamal-Deen, Yang, Mengsu, Lam, Yun Wah, Roy, Vellaisamy A. L., Lau, Condon“…[Image: see text] The impact of radiation-induced bystander effect (RIBE) is still not well understood in radiotherapy. …”
Publicado 2021
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292por Gnanagobal, Hajarooba, Cao, Trung, Hossain, Ahmed, Vasquez, Ignacio, Chakraborty, Setu, Chukwu-Osazuwa, Joy, Boyce, Danny, Espinoza, María Jesus, García-Angulo, Víctor Antonio, Santander, Javier“…Monocistronic mRNA ribA, ribB and ribE2 encode for their corresponding functional riboflavin biosynthetic enzyme. …”
Publicado 2023
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293por Zhang, Jianghong, Zhang, Yuhong, Mo, Fang, Patel, Gaurang, Butterworth, Karl, Shao, Chunlin, Prise, Kevin M.“…Radiation-induced bystander effects (RIBE) may have potential implications for radiotherapy, yet the radiobiological impact and underlying mechanisms in hypoxic tumor cells remain to be determined. …”
Publicado 2021
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294“…The radiation-induced bystander effect (RIBE) is the initiation of biological end points in cells (bystander cells) that are not directly traversed by an incident-radiation track, but are in close proximity to cells that are receiving the radiation. …”
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295por Zhang, Liying, Luo, Yali, Lu, Zhiwei, He, Jinpeng, Wang, Lei, Zhang, Lixin, Zhang, Yiming, Liu, Yongqi“…BACKGROUND: This study investigated the effect of Astragalus polysaccharides (APS) on radiation-induced bystander effects (RIBE) in human bone mesenchymal stem cells (BMSCs) induced by irradiated A549 cells. …”
Publicado 2018
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296“…This study aimed to determine whether the radiation-induced bystander effect (RIBE) is affected by radiation quality. To mimic the different radiation qualities of the direct action (D)/indirect action (ID) ratio, A549 cells were exposed to X-rays, with either 100 mM of the radical scavenger, thio-urea (TU(+)), or null (TU(–)). …”
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297por Alcaraz, Miguel, Olivares, Amparo, Andreu-Gálvez, Marina, Achel, Daniel Gyingiri, Mercado, Ana María, Alcaraz-Saura, Miguel“…We evaluated the radioprotective capacity of CA on cells directly exposed to X-rays and non-irradiated cells that received signals from X-ray treated cells (radiation induced bystander effect, RIBE). The genoprotective capacity was studied by in vivo and in vitro micronucleus assays. …”
Publicado 2022
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298por Sorlozano-Puerto, Antonio, Lopez-Machado, Isaac, Albertuz-Crespo, Maria, Martinez-Gonzalez, Luis Javier, Gutierrez-Fernandez, Jose“…We amplified and sequenced murA, glpT, uhpT, uhpA, ptsI, cyaA, nfsA, nfsB, and ribE genes, and screened plasmid-borne fosfomycin-resistance genes fosA3, fosA4, fosA5, fosA6, and fosC2 and nitrofurantoin-resistance genes oqxA and oqxB by polymerase chain reaction. …”
Publicado 2020
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299por Rotter, Daniel Andreas Orlando, Heger, Christoph, Kühm, Christian, Schmidt, Nina, Schäfer, Antje, Heimerl, Thomas, Mack, Matthias, Graumann, Peter L.“…Bacterial two-hybrid system revealed interactions between RibT, RibH, and RibE, forming the heavy RF synthase complex. Applying single particle tracking (SPT), we found that confined (sub)diffusion of RibT is largely dependent on interacting RibE and, to a lesser degree, on interacting RibH. …”
Publicado 2022
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300“…The radiation-induced bystander effect (RIBE) has been experimentally observed for different types of radiation, cell types, and cell culture conditions. …”
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