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541por Dobrzanski, Tatiane, Pobre, Vânia, Moreno, Leandro Ferreira, Barbosa, Helba Cirino de Souza, Monteiro, Rose Adele, de Oliveira Pedrosa, Fábio, de Souza, Emanuel Maltempi, Arraiano, Cecília Maria, Steffens, Maria Berenice Reynaud“…RESULTS: This approach resulted in a set of 117 sRNAs distributed in riboswitch, cis-encoded and trans-encoded categories and among them 20 have Rfam homologs. …”
Publicado 2020
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542por Ramakrishnan, Saminathan, Stagno, Jason R., Conrad, Chelsie E., Ding, Jienyu, Yu, Ping, Bhandari, Yuba R., Lee, Yun-Tzai, Pauly, Gary, Yefanov, Oleksandr, Wiedorn, Max O., Knoska, Juraj, Oberthür, Dominik, White, Thomas A., Barty, Anton, Mariani, Valerio, Li, Chufeng, Brehm, Wolfgang, Heinz, William F., Magidson, Valentin, Lockett, Stephen, Hunter, Mark S., Boutet, Sébastien, Zatsepin, Nadia A., Zuo, Xiaobing, Grant, Thomas D., Pandey, Suraj, Schmidt, Marius, Spence, John C. H., Chapman, Henry N., Wang, Yun-Xing“…Here we report the synchronous behavior of the adenine riboswitch aptamer RNA in crystal during ligand-triggered isothermal phase transitions. …”
Publicado 2021
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543por Srivastava, Yoshita, Bonn-Breach, Rachel, Chavali, Sai Shashank, Lippa, Geoffrey M., Jenkins, Jermaine L., Wedekind, Joseph E.“…Crystals were also attained of U1A(F37M/F77M) in complex with a bacterial preQ(1)-II riboswitch. The F34M/F37M/F77M mutant was introduced similarly into a lab-evolved U1A variant (TBP6.9) that recognizes the internal bulged loop of HIV-1 TAR RNA. …”
Publicado 2021
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544“…As an example, we have performed the learning of three Boltzmann machines modeling the Kunitz and Beta-lactamase2 protein domains and TPP-riboswitch RNA domain. CONCLUSIONS: The models learned by adabmDCA are comparable to those obtained by state-of-the-art techniques for this task, in terms of the quality of the inferred contact map as well as of the synthetically generated sequences. …”
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545por Higashi, Dustin L., McGuire, Sean, Abdelrahman, Yasser M., Zou, Zhengzhong, Qin, Hua, Anderson, David, Palmer, Elizabeth A., Kreth, Jens, Merritt, Justin“…This reporter system was then applied for the development of the novel Theo+ theophylline-inducible riboswitch for tunable gene expression studies over a broad dynamic range. …”
Publicado 2022
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546por Hernández-Alcántara, Annel M., Chiva, Rosana, Mohedano, María Luz, Russo, Pasquale, Ruiz-Masó, José Ángel, del Solar, Gloria, Spano, Giuseppe, Tamame, Mercedes, López, Paloma“…These mutations, which map in the sensor domain (aptamer) of a regulatory element (the so-called FMN riboswitch) present in the 5’ untranslated region of the rib operon mRNA, appear to be responsible for the riboflavin-overproducing phenotype of the BAL3C-5 B2, BAL3C-7 B2, and BAL3C-22 B2 mutant strains. …”
Publicado 2022
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547“…We analyze a sample TPP riboswitch, and apply our algorithm to the class of purine riboswitches. …”
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548por Smith, Daniel P., Nicora, Carrie D., Carini, Paul, Lipton, Mary S., Norbeck, Angela D., Smith, Richard D., Giovannoni, Stephen J.“…Many of the genes and SAM riboswitches involved in this response are located in a hypervariable genome region (HVR). …”
Publicado 2016
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549por Sun, Tao, Li, Shubin, Song, Xinyu, Pei, Guangsheng, Diao, Jinjin, Cui, Jinyu, Shi, Mengliang, Chen, Lei, Zhang, Weiwen“…Finally, the Hfq-MicC system was further modified into an inducible system based on the theophylline-inducible riboswitch. CONCLUSIONS: In this study, two small RNA regulatory tools for manipulating essential metabolic pathways and re-directing carbon flux are reported for Synechocystis sp. …”
Publicado 2018
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550por Cortes, Bienvenido W., Naditz, Annabel L., Anast, Justin M., Schmitz-Esser, Stephan“…Furthermore, an average of 65% of all mapped transcriptome reads for the R479a plasmid following acid stress were mapped to an intergenic region bearing similarity to riboswitches involved in transition metal resistance. …”
Publicado 2020
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551“…Surveying DE transcripts for known ncRNAs from the Rfam database identified a large number of tRNAs and tmRNAs as well as riboswitches (FMN, glycine, lysine, and SAM) in more prevalent transcripts and the cobalamin riboswitch in both more and less prevalent transcripts. …”
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552por Zeng, Zhe, Boeren, Sjef, Bhandula, Varaang, Light, Samuel H., Smid, Eddy J., Notebaart, Richard A., Abee, Tjakko“…Despite reports showing that the activation of eut is regulated by a vitamin B(12)-binding riboswitch and that upregulation of eut genes occurs in mice, it remains unknown whether EA catabolism is BMC dependent in Listeria monocytogenes. …”
Publicado 2021
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553por Jäger, Dominik, Förstner, Konrad U, Sharma, Cynthia M, Santangelo, Thomas J, Reeve, John N“…The results identify TSS for 1,018 antisense transcripts, most with sequences complementary to either the 5'- or 3'-region of a sense mRNA, and confirm the presence of transcripts from all three CRISPR loci, the RNase P and 7S RNAs, all tRNAs and rRNAs and 69 predicted snoRNAs. Two putative riboswitch RNAs were present in growing but not in stationary phase cells. …”
Publicado 2014
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554por Eckdahl, Todd T., Campbell, A. Malcolm, Heyer, Laurie J., Poet, Jeffrey L., Blauch, David N., Snyder, Nicole L., Atchley, Dustin T., Baker, Erich J., Brown, Micah, Brunner, Elizabeth C., Callen, Sean A., Campbell, Jesse S., Carr, Caleb J., Carr, David R., Chadinha, Spencer A., Chester, Grace I., Chester, Josh, Clarkson, Ben R., Cochran, Kelly E., Doherty, Shannon E., Doyle, Catherine, Dwyer, Sarah, Edlin, Linnea M., Evans, Rebecca A., Fluharty, Taylor, Frederick, Janna, Galeota-Sprung, Jonah, Gammon, Betsy L., Grieshaber, Brandon, Gronniger, Jessica, Gutteridge, Katelyn, Henningsen, Joel, Isom, Bradley, Itell, Hannah L., Keffeler, Erica C., Lantz, Andrew J., Lim, Jonathan N., McGuire, Erin P., Moore, Alexander K., Morton, Jerrad, Nakano, Meredith, Pearson, Sara A., Perkins, Virginia, Parrish, Phoebe, Pierson, Claire E., Polpityaarachchige, Sachith, Quaney, Michael J., Slattery, Abagael, Smith, Kathryn E., Spell, Jackson, Spencer, Morgan, Taye, Telavive, Trueblood, Kamay, Vrana, Caroline J., Whitesides, E. Tucker“…We used a theophylline riboswitch and a tetracycline resistance gene to link theophylline production to fitness. …”
Publicado 2015
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555“…Fourteen sRNAs were induced in high Fe conditions, consisting of both cis and trans sRNAs, some of which are predicted to control expression of a known virulence factor, and one SAM riboswitch. An additional putative cis-acting sRNA was repressed by Fe availability. …”
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556por Zou, Xia, Ren, Zhenxing, Wang, Na, Cheng, Yin, Jiang, Yuanyuan, Wang, Yan, Xu, Chenggang“…Thus, it is speculated that 5′-UTR of xyl-doc was a putative riboswitch to regulate the expression of downstream cellulosomal genes, which is helpful to understand the complex regulation of cellulosome. …”
Publicado 2018
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557por Tran, Thao, Liu, Yuanyuan, Marchant, Jan, Monti, Sarah, Seu, Michelle, Zaki, Jessica, Yang, Ae Lim, Bohn, Jennifer, Ramakrishnan, Venkateswaran, Singh, Rashmi, Hernandez, Mateo, Vega, Alexander, Summers, Michael F.“…Although NC is a well-known RNA chaperone, its role in dimerization has the hallmarks of a classical riboswitch.…”
Publicado 2015
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558por Xiu, Yu, Zhang, Ni, Prabhakaran, Pranesha, Jang, Sungho, Yuan, Qipeng, Breneman, Curt M., Jung, Gyoo Yeol, Vongsangnak, Wanwipa, Koffas, Mattheos A.G.“…Riboswitches O and L preferred multi-hydroxylated flavones as ligands. …”
Publicado 2022
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559“…This is especially true for riboswitches, which are natural ligand-binding regulators of gene expression. …”
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560por Rai, Navneet, Ferreiro, Aura, Neckelmann, Alexander, Soon, Amy, Yao, Andrew, Siegel, Justin, Facciotti, Marc T., Tagkopoulos, Ilias“…Here, we present RiboTALEs, a new class of inducible repressors that combine the specificity of TALEs with the ability of riboswitches to recognize exogenous signals and differentially control protein abundance. …”
Publicado 2015
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