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621“…Additionally, we discuss how targeting small RNAs and riboswitches, as well as antimicrobial peptides, would help combat drug-resistant infections in the near future.…”
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622“…Moreover, cyanobacteria evolved unique RNA-based regulatory mechanisms such as glutamine riboswitches to tightly tune IF abundance. In this review, we aim to outline the current knowledge on the distinctive features of the cyanobacterial GS encompassing the overall control of its activity, sensing the nitrogen status, transcriptional and post-transcriptional regulation, as well as strain-specific differences.…”
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623“…Recently developed high-throughput techniques, such as genomic tiling arrays and RNA-Seq have allowed investigating prokaryotic cis- and trans-acting regulatory RNAs, including sRNAs, asRNAs, untranslated regions (UTR) and riboswitches. As a result, we obtained a more comprehensive view on the complexity and plasticity of the prokaryotic genome biology. …”
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624“…Higher order RNA structures can mask splicing signals, loop out exons, or constitute riboswitches all of which contributes to the complexity of splicing regulation. …”
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625por Boutard, Magali, Ettwiller, Laurence, Cerisy, Tristan, Alberti, Adriana, Labadie, Karine, Salanoubat, Marcel, Schildkraut, Ira, Tolonen, Andrew C.“…We show that TSS reveals riboswitches, non-coding RNA and novel transcription units. …”
Publicado 2016
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626por Miao, Zhichao, Adamiak, Ryszard W., Antczak, Maciej, Boniecki, Michał J., Bujnicki, Janusz, Chen, Shi-Jie, Cheng, Clarence Yu, Cheng, Yi, Chou, Fang-Chieh, Das, Rhiju, Dokholyan, Nikolay V., Ding, Feng, Geniesse, Caleb, Jiang, Yangwei, Joshi, Astha, Krokhotin, Andrey, Magnus, Marcin, Mailhot, Olivier, Major, Francois, Mann, Thomas H., Piątkowski, Paweł, Pluta, Radoslaw, Popenda, Mariusz, Sarzynska, Joanna, Sun, Lizhen, Szachniuk, Marta, Tian, Siqi, Wang, Jian, Wang, Jun, Watkins, Andrew M., Wiedemann, Jakub, Xiao, Yi, Xu, Xiaojun, Yesselman, Joseph D., Zhang, Dong, Zhang, Yi, Zhang, Zhenzhen, Zhao, Chenhan, Zhao, Peinan, Zhou, Yuanzhe, Zok, Tomasz, Żyła, Adriana, Ren, Aiming, Batey, Robert T., Golden, Barbara L., Huang, Lin, Lilley, David M., Liu, Yijin, Patel, Dinshaw J., Westhof, Eric“…We now report the prediction of 3D structures for six RNA sequences: four nucleolytic ribozymes and two riboswitches. Systematic protocols for comparing models and crystal structures are described and analyzed. …”
Publicado 2020
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627Cobalamin is present in cells of non-tuberculous mycobacteria, but not in Mycobacterium tuberculosispor Minias, Alina, Gąsior, Filip, Brzostek, Anna, Jagielski, Tomasz, Dziadek, Jarosław“…Cobalamin (vitamin B12) is a structurally complex molecule that acts as a cofactor for enzymes and regulates gene expression through so-called riboswitches. The existing literature on the vitamin B12 synthesis capacity in Mycobacterium tuberculosis is ambiguous, while in non-tuberculous mycobacteria (NTM) is rather marginal. …”
Publicado 2021
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628“…This article is categorized under: Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs. RNA in Disease and Development > RNA in Disease.…”
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629“…Riboregulators such as riboswitches and RNA thermometers provide simple, protein-independent tools to control gene expression at the post-transcriptional level. …”
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630por Goelzer, Anne, Bekkal Brikci, Fadia, Martin-Verstraete, Isabelle, Noirot, Philippe, Bessières, Philippe, Aymerich, Stéphane, Fromion, Vincent“…However, metabolite pools link the metabolic to the genetic network through genetic regulations, including those involving effectors of transcription factors or riboswitches. Consequently, they play pivotal roles in the global organization of the genetic and metabolic regulatory networks. …”
Publicado 2008
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631por Lukasiak, Piotr, Antczak, Maciej, Ratajczak, Tomasz, Bujnicki, Janusz M., Szachniuk, Marta, Adamiak, Ryszard W., Popenda, Mariusz, Blazewicz, Jacek“…Contemporary functional analysis of RNA molecules, such as ribozymes or riboswitches, covers various issues, among which tertiary structure modeling becomes more and more important. …”
Publicado 2013
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632“…In addition, their shared characteristics such as CU interaction motifs, the role of Hfq, and involvement in two-component regulators, riboswitches, quorum sensing, or toxin/antitoxin systems are described.…”
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633por Liu, Yuchen, Han, Jinghong, Chen, Zhicong, Wu, Hanwei, Dong, Hongsong, Nie, Guohui“…Moreover, we construct programmable ligand-controlled dAsCpf1 systems either by coupling crRNAs with engineered riboswitches or by fusing dAsCpf1 proteins with G protein-coupled receptors. …”
Publicado 2017
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634“…T-box riboswitches are modular bacterial noncoding RNAs that sense and regulate amino-acid availability through direct interactions with tRNAs. …”
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635por Gee, Peter, Lung, Mandy S. Y., Okuzaki, Yuya, Sasakawa, Noriko, Iguchi, Takahiro, Makita, Yukimasa, Hozumi, Hiroyuki, Miura, Yasutomo, Yang, Lucy F., Iwasaki, Mio, Wang, Xiou H., Waller, Matthew A., Shirai, Nanako, Abe, Yasuko O., Fujita, Yoko, Watanabe, Kei, Kagita, Akihiro, Iwabuchi, Kumiko A., Yasuda, Masahiko, Xu, Huaigeng, Noda, Takeshi, Komano, Jun, Sakurai, Hidetoshi, Inukai, Naoto, Hotta, Akitsu“…Chemical induced dimerization recruits Cas9 protein into extracellular nanovesicles, and then a viral RNA packaging signal and two self-cleaving riboswitches tether and release sgRNA into nanovesicles. …”
Publicado 2020
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636“…For the two structures in the 3′ UTRs of the metabolic genes GLY1 and MET13, we performed experiments that provide evidence against them being eukaryotic riboswitches.…”
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637por Chauvier, Adrien, St-Pierre, Patrick, Nadon, Jean-François, Hien, Elsa D. M., Pérez-González, Cibrán, Eschbach, Sébastien H., Lamontagne, Anne-Marie, Penedo, J. Carlos, Lafontaine, Daniel A.“…By monitoring Escherichia coli nascent riboswitches, we reveal an inverse relationship between elongation speed and metabolite-sensing efficiency and show that pause sites upstream of the translation start codon delimit a sequence hotspot for metabolite sensing during transcription. …”
Publicado 2021
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638por Chen, Chaoxin, Wu, Qi, Ke, Qingying, Wang, Ting, Zhang, Yifan, Wei, Feiwen, Wang, Xiaolong, Liu, Guanglei“…To date, several different types of synthetic genetic switches, including riboregulators, riboswitches, and toehold switches, have been developed to construct AND, OR, NOT, NAND, NOR, and NOT IMPLICATION (NIMP) gates. …”
Publicado 2022
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639por Costa, Vanessa G., Costa, Susana M., Saramago, Margarida, Cunha, Marta V., Arraiano, Cecília M., Viegas, Sandra C., Matos, Rute G.“…A long scientific journey has led to prominent technological advances in the RNA field, and several new types of molecules have been discovered, from non-coding RNAs (ncRNAs) to riboswitches, small interfering RNAs (siRNAs) and CRISPR systems. …”
Publicado 2022
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640“…Riboswitches and RNA interference are important emerging mechanisms found in many organisms to control gene expression. …”
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