Mostrando 61 - 80 Resultados de 734 Para Buscar '"Riboswitch"', tiempo de consulta: 0.40s Limitar resultados
  1. 61
    “…While the structure and molecular dynamics of the tandem glycine riboswitch have been the subject of numerous in vitro studies, the in vivo behavior of the riboswitch remains largely uncharacterized. …”
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    In Vivo Behavior of the Tandem Glycine Riboswitch in Bacillus subtilis
  2. 62
    “…In Gram-positive bacteria, T-box riboswitches control gene expression to maintain the cellular pools of aminoacylated tRNAs essential for protein biosynthesis. …”
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    Hierarchical mechanism of amino acid sensing by the T-box riboswitch
  3. 63
    por Abduljalil, Jameel M.
    Publicado 2018
    “…In depth understanding of riboswitches is promising for opportunity to discover a narrow spectrum antibacterial drugs that target riboswitches of essential metabolic pathways.…”
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    Bacterial riboswitches and RNA thermometers: Nature and contributions to pathogenesis
  4. 64
    por Tamayo, Rita
    Publicado 2019
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    Cyclic diguanylate riboswitches control bacterial pathogenesis mechanisms
  5. 65
    “…Riboswitches are metabolite-sensing, conserved domains located in non-coding regions of mRNA that are central to regulation of gene expression. …”
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    SAM-VI riboswitch structure and signature for ligand discrimination
  6. 66
    “…However, a significant proportion of glycine riboswitches are comprised of single aptamers (singleton). …”
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    Regulatory context drives conservation of glycine riboswitch aptamers
  7. 67
    por Yokobayashi, Yohei
    Publicado 2019
    “…These mammalian synthetic riboswitches offer attractive features such as small genetic size and lower risk of immunological complications compared to protein-based transcriptional gene switches. …”
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    Aptamer-based and aptazyme-based riboswitches in mammalian cells
  8. 68
    “…Artificial riboswitches based on ribozymes serve as versatile tools for ligand-dependent gene expression regulation. …”
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    Expanding the toolbox of synthetic riboswitches with guanine-dependent aptazymes
  9. 69
    “…Riboswitches are RNAs that specifically sense a small molecule and regulate genes accordingly. …”
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    Discovery and characterization of a fourth class of guanidine riboswitches
  10. 70
    “…These bioinformatic and biochemical findings indicate that pnuC motif RNAs are likely members of a second riboswitch class that regulates gene expression in response to NAD(+) binding.…”
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    A second riboswitch class for the enzyme cofactor NAD(+)
  11. 71
    “…Here, we disclose the thus far unrecognized direct link between a present-day riboswitch and its inherent reactivity for site-specific methylation. …”
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    A natural riboswitch scaffold with self-methylation activity
  12. 72
    “…In recent years, synthetic riboswitches have become increasingly important to construct genetic circuits in all three domains of life. …”
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    A Synthetic Riboswitch to Regulate Haloarchaeal Gene Expression
  13. 73
    “…SAM-I riboswitches regulate gene expression through transcription termination upon binding a S-adenosyl-L-methionine (SAM) ligand. …”
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    Exploring the energy landscape of a SAM-I riboswitch
  14. 74
    “…In bacteria, expression of folate-related genes is controlled by the tetrahydrofolate (THF) riboswitch in response to specific binding of THF and its derivatives. …”
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    Structural insights into translation regulation by the THF-II riboswitch
  15. 75
    por Kelvin, Daniel, Suess, Beatrix
    Publicado 2023
    “…While naturally occurring riboswitches were mostly discovered in bacteria, synthetic riboswitches have been designed for all domains of life. …”
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    Tapping the potential of synthetic riboswitches: reviewing the versatility of the tetracycline aptamer
  16. 76
    “…The Bacillus subtilis lysC lysine riboswitch modulates its own gene expression upon lysine binding through a transcription attenuation mechanism. …”
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    Folding of the lysine riboswitch: importance of peripheral elements for transcriptional regulation
  17. 77
    “…The mfl-riboswitch regulates expression of ribonucleotide reductase subunit in Mesoplasma florum by binding to 2′-deoxyguanosine and thereby promoting transcription termination. …”
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    Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy
  18. 78
    “…Here we describe the characterization and application of a synthetic riboswitch-based system, which comprises a mycobacterial promoter for transcriptional control and a riboswitch for translational control. …”
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    A Riboswitch-Based Inducible Gene Expression System for Mycobacteria
  19. 79
    “…Many bacterial genes are controlled by metabolite sensing motifs known as riboswitches, normally located in the 5′ un-translated region of their mRNAs. …”
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    Atomistic basis for the on–off signaling mechanism in SAM-II riboswitch
  20. 80
    por Singh, Payal, Sengupta, Supratim
    Publicado 2012
    “…Riboswitches are regulatory RNA that control gene expression by undergoing conformational changes on ligand binding. …”
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    Phylogenetic Analysis and Comparative Genomics of Purine Riboswitch Distribution in Prokaryotes
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