Mostrando 141 - 160 Resultados de 734 Para Buscar '"Riboswitch"', tiempo de consulta: 0.17s Limitar resultados
  1. 141
    “…Translational riboswitches are cis-acting RNA regulators that modulate the expression of genes during translation initiation. …”
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    Switching at the ribosome: riboswitches need rProteins as modulators to regulate translation
  2. 142
    “…T-box riboswitches (T-boxes) are essential RNA regulatory elements with a remarkable structural diversity, especially among bacterial pathogens. …”
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    Lineage-specific insertions in T-box riboswitches modulate antibiotic binding and action
  3. 143
    por Pavlova, Nikolet, Penchovsky, Robert
    Publicado 2022
    “…This article presents in silico analyses of eight bacterial riboswitches for their suitability for antibacterial drug targets. …”
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    Bioinformatics and Genomic Analyses of the Suitability of Eight Riboswitches for Antibacterial Drug Targets
  4. 144
    “…We compared several tetracycline and toyocamycin-inducible ON-riboswitches for a drug responsive transgene expression. …”
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    Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy
  5. 145
    “…Riboswitches are promising regulatory tools in synthetic biology. …”
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    Systematic Comparison and Rational Design of Theophylline Riboswitches for Effective Gene Repression
  6. 146
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    Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy
  7. 147
    por Hu, Guodong, Zhou, Huan-Xiang
    Publicado 2023
    “…The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. …”
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    Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch
  8. 148
    “…Riboswitches are 5’‐untranslated mRNA regions mostly found in bacteria. …”
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    Carba‐Sugar Analogs of Glucosamine‐6‐Phosphate: New Activators for the glmS Riboswitch
  9. 149
    “…Here, we exploited the sensor capabilities of a Z-nucleotide-sensing riboswitch to create an experimental system able to identify physicochemical and structural properties of compounds that permeate the bacterial cell, avoid efflux, and perturb the folate cycle or de novo purine synthesis. …”
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    Identification of Efflux Substrates Using a Riboswitch-Based Reporter in Pseudomonas aeruginosa
  10. 150
    por Hu, Guodong, Zhou, Huan-Xiang
    Publicado 2023
    “…The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. …”
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    Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch
  11. 151
    “…Riboswitches are regulatory elements found in bacterial mRNAs that control downstream gene expression through ligand-induced conformational changes. …”
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    Linking folding dynamics and function of SAM/SAH riboswitches at the single molecule level
  12. 152
    “…It has been recently reported that riboswitch agonists may exhibit antimicrobial properties by binding to the riboswitch domain. …”
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    Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine-Related Metabolic Pathways
  13. 153
    “…In conclusion, our study demonstrates the fidelity of aptazymes in viral vectors and oncolytic viruses and highlights the potency of riboswitches for medical applications.…”
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    Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses
  14. 154
    “…We find that some sequence variations in the k-turn within the riboswitch do not prevent SAM binding, despite preventing the folding of the k-turn in isolation. …”
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    RNA Tertiary Interactions in a Riboswitch Stabilize the Structure of a Kink Turn
  15. 155
    “…Riboswitches are mRNA-based molecules capable of controlling the expression of genes. …”
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    Loop–loop interaction in an adenine-sensing riboswitch: A molecular dynamics study
  16. 156
    “…[Image: see text] The glmS riboswitch is unique among gene-regulating riboswitches and catalytic RNAs. …”
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    Phosphatase-Inert Glucosamine 6-Phosphate Mimics Serve as Actuators of the glmS Riboswitch
  17. 157
    “…INTRODUCTION: Riboswitches are cis-acting regulatory RNA elements prevalently located in the leader sequences of bacterial mRNA. …”
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    Kissing loop interaction in adenine riboswitch: insights from umbrella sampling simulations
  18. 158
    “…Riboswitches are shape-changing regulatory RNAs that bind chemicals and regulate gene expression, directly coupling sensing to cellular actuation. …”
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    Automated physics-based design of synthetic riboswitches from diverse RNA aptamers
  19. 159
    “…Two prominent examples are the RNase P ribozyme and the T-box riboswitch. Both act as molecular calipers. The two RNAs clamp onto the elbow of tRNA (or pre-tRNA) and make distance measurements orthogonal to each other. …”
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    Trying on tRNA for Size: RNase P and the T-box Riboswitch as Molecular Rulers
  20. 160
    “…Efforts to control mammalian gene expression with ligand-responsive riboswitches have been hindered by lack of a general method for generating efficient switches in mammalian systems. …”
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    Rational design of aptazyme riboswitches for efficient control of gene expression in mammalian cells
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