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841por Jo, Peter, Nietert, Manuel, Gusky, Linda, Kitz, Julia, Conradi, Lena C., Müller-Dornieden, Annegret, Schüler, Philipp, Wolff, Hendrik A., Rüschoff, Josef, Ströbel, Philipp, Grade, Marian, Liersch, Torsten, Beißbarth, Tim, Ghadimi, Michael B., Sax, Ulrich, Gaedcke, Jochen“…The cellular content of tumor, mucosa, stroma, necrosis and the amount of isolated DNA and RNA as well as the RNA integrity number (RIN) as quality parameters were evaluated. A high RNA yield (p = 2.75e–07) and the content of tumor (p = 0.004) is significantly associated to high RIN-values, whereas a high content of mucosa (p = 0.07) shows a trend and a high amount of necrosis (p = 0.01) is significantly associated with RNA of poor quality. …”
Publicado 2016
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842por Niu, Yuzhen, Shi, Danfeng, Li, Lanlan, Guo, Jingyun, Liu, Huanxiang, Yao, Xiaojun“…Residues H252, D256, L267, Y335, G336 and H339 are responsible for the binding of SETD7 to the (R)-PFI-2. RIN analysis indicates van der Waals interaction is critical for the binding of (R)-PFI-2. …”
Publicado 2017
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843por Mavrich, Travis N., Casey, Eoghan, Oliveira, Joana, Bottacini, Francesca, James, Kieran, Franz, Charles M. A. P., Lugli, Gabriele Andrea, Neve, Horst, Ventura, Marco, Hatfull, Graham F., Mahony, Jennifer, van Sinderen, Douwe“…Interestingly, several of these phages harbor a putative phase variation shufflon (the Rin system) that generates variation of the tail-associated receptor binding protein (RBP). …”
Publicado 2018
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844por Ahmed, Qamar Uddin, Sarian, Murni Nazira, Mat So’ad, Siti Zaiton, Latip, Jalifah, Arief Ichwan, Solachuddin Jauhari, Hussein, Nurlaili Najmie, Taher, Muhammad, Alhassan, Alhassan Muhammad, Hamidon, Hanisuhana, Fakurazi, Sharida“…Hence, in the present study, 14 structurally related flavonoids viz. wogonin, techtochrysin, norwogonin, isoscutellarein, hypolaetin, kaempferol, quercetin, methyl ether of wogonin, acetate of wogonin, acetate of norwogonin, 8-hydroxy-7-methoxyflavone, chrysin, (+)-catechin and (-)-epicatechin were taken into account for in vitro antidiabetic evaluation. Cell viability of RIN-5F pancreatic cells and 3T3-L1 pre-adipocyte cells was initially tested, then an insulin secretion assay of RIN-5F as well as adipogenesis and glucose uptake measurements of adipocyte were investigated. …”
Publicado 2018
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845por Osorio, Sonia, Carneiro, Raphael T., Lytovchenko, Anna, McQuinn, Ryan, Sørensen, Iben, Vallarino, José G., Giovannoni, James J., Fernie, Alisdair R., Rose, Jocelyn K. C.“…Tomato (Solanum lycopersicum) fruit ripening is regulated co‐operatively by the action of ethylene and a hierarchy of transcription factors, including RIPENING INHIBITOR (RIN) and NON‐RIPENING (NOR). Mutations in these two genes have been adopted commercially to delay ripening, and accompanying textural deterioration, as a means to prolong shelf life. …”
Publicado 2019
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846RNA profile diversity across arthropoda: guidelines, methodological artifacts, and expected outcomespor DeLeo, Danielle M, Pérez-Moreno, Jorge L, Vázquez-Miranda, Hernán, Bracken-Grissom, Heather D“…However, the primary metric used to assess RNA quality, the RNA Integrity Number (RIN), was developed based on model bacterial and vertebrate organisms. …”
Publicado 2018
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847por Sullivan, Roisin, Heavey, Susan, Graham, David G., Wellman, Rachel, Khan, Saif, Thrumurthy, Sri, Simpson, Benjamin S., Baker, Tina, Jevons, Sarah, Ariza, Jose, Eneh, Victor, Pye, Hayley, Luxton, Hayley, Hamoudi, Rifat, Whitaker, Hayley, Lovat, Laurence B.“…There was a trend towards higher RNA concentration when saliva was collected after overnight fasting but no effect on RIN. In the clinic, RNA yields of 6307 ng and RINs of 3.9 were achieved, improving on previous reports. …”
Publicado 2020
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848por Nair, Ajikumaran Nair Sadasivan, Nair, Reshma Vijayakumari Raveendran, Nair, Aroma Prasanna Rajendran, Nair, Akhila Sasikumar, Thyagarajan, Sabu, Johnson, Anil John, Baby, Sabulal“…Cytoprotective activity of (CA+24-MCA) from glucose toxicity was evaluated in cultured RIN-5F cells by MTT assay and fluorescent microscopy. …”
Publicado 2020
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849por Zhao, Tongjian, Ma, Jie, Li, Lulu, Teng, Wenjing, Tian, Yafei, Ma, Yongjun, Wang, Wei, Yan, Weiqun, Jiao, Ping“…We found that MKP-5 overexpression restored PA-mediated autophagy inhibition in Rin-m5f cells and protected these cells from PA-induced apoptosis and dysfunction. …”
Publicado 2020
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850Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII“…Here, we addressed this issue by creating a residue interaction network (RIN) where the nodes are the FVIII residues, and two nodes are connected if their corresponding residues are in close proximity in the FVIII protein structure. …”
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851por Kim, Seung-Goo, Overath, Tobias, Sedley, William, Kumar, Sukhbinder, Teki, Sundeep, Kikuchi, Yukiko, Patterson, Roy, Griffiths, Timothy D.“…The regularity-onset responses for RIN were much weaker than for the other types of regular stimuli (HC, CT). …”
Publicado 2022
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852por Pakarinen, Janne, Voulot, D, Wenander, F, Simpson, J, Kröll, Th, Davinson, T, Clément, E, Grahn, T, Greenlees, P T, Jones, P, Julin, R, Konki, J, Rahkila, P, Sorri, J, Blazhev, A, Jolie, J, Reiter, P, Warr, N, Huyse, M, Van Duppen, P, Darby, I, Van de Walle, J, Butler, P A, Herzberg, R D, Joss, D T, Page, R D, Papadakis, P, Scheck, M, Cederkäll, J, Orlandi, R, Bildstein, V, Gernhäuser, R, Krücken, R, Wimmer, K, Thirolf, P, Bürger, A, Guttormsen, M, Larsen, A C, Nyhus, H T, Siem, S, Tveten, G M, Cline, D, Hayes, A, Goergen, A, Korten, W, Hadynska, K, Iwanicki, J, Napiorkowski, P, Piẹtak, D, Srebrny, J, Wrzosek, K, Zielinska, M, Palacz, M, Jaworski, G, Andreyev, A, Smith, J F, Barton, C, Jenkins, D G, Wadsworth, REnlace del recurso
Publicado 2010
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853por Zhang, Zaijun, Jiang, Jie, Yu, Pei, Zeng, Xiangping, Larrick, James W, Wang, Yuqiang“…Translocation of glucose transporter subtype 4 in soleus muscle was detected by western blot. In RIN-m cells in vitro, the effect of AL-1 on H(2)O(2)-induced damage and reactive oxidative species production stimulated by high glucose and glibenclamide were measured. …”
Publicado 2009
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854“…CONCLUSIONS: This study indicates that SlSR expression is influenced by both the Rin-mediated developmental network and ethylene signaling. …”
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855por Ranjbari, Abbas, Azarbayjani, Mohammad Ali, Yusof, Ashril, Halim Mokhtar, Abdul, Akbarzadeh, Samad, Ibrahim, Mohamed Yousif, Tarverdizadeh, Bahman, Farzadinia, Parviz, Hajiaghaee, Reza, Dehghan, Firouzeh“…The effect of UD on insulin secretion by RIN-5F cells in 6.25 or 12.5 mM glucose dose was examined. …”
Publicado 2016
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856por Ruocco, Nadia, Costantini, Susan, Zupo, Valerio, Romano, Giovanna, Ianora, Adrianna, Fontana, Angelo, Costantini, Maria“…The Bioanalyzer profiles and RIN values revealed that the most efficient methods guaranteeing for RNA integrity were RNeasy and Aurum combined with an initial preservation in RNAlater. …”
Publicado 2017
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857por Kumar, Shiv, Patial, Vikram, Soni, Sourabh, Sharma, Supriya, Pratap, Kunal, Kumar, Dinesh, Padwad, Yogendra“…It significantly (p ≤ 0.05) enhanced the insulin expression and aids in proliferation of insulin producing Rin5f cells with elevated insulin secretion. Furthermore it significantly (p ≤ 0.05) increased insulin mediated glucose uptake in 3T3L1 and L6 cells. …”
Publicado 2017
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858“…The numerical predictions are confirmed by RIN measurements of fs-pumped ANDi fiber SC.…”
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859por Grinstein, Mor, Dingwall, Heather L., Shah, Rishita R., Capellini, Terence D., Galloway, Jenna L.“…RESULTS: After testing several RNA extraction approaches on single adult mouse Achilles tendons, we developed a protocol that was successful at obtaining high RIN and sufficient concentrations suitable for RNA analysis. …”
Publicado 2018
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860“…Residue interaction network (RIN) analysis found greater clustering of residues 112–117 in amyloidogenic variants of lysozyme compared to wild type. …”
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