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501por Yang, Guanci, Yang, Jing, Sheng, Weihua, Junior, Francisco Erivaldo Fernandes, Li, Shaobo“…Finally, we compared the results among RODA-FY, Inception V3, and YOLO, which indicate that our proposed RODA-FY outperforms the other comparison models in recognition accuracy.…”
Publicado 2018
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502por Brown, Neil Andrew, Ries, Laure N. A., Reis, Thaila F., Rajendran, Ranjith, Corrêa dos Santos, Renato Augusto, Ramage, Gordon, Riaño-Pachón, Diego Mauricio, Goldman, Gustavo H.“…The major hydrophobin, RodA, was retained within the fungal biofilm on SEB fibres. …”
Publicado 2016
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503“…The rodA gene was anticipated to be related to peptidoglycan synthesis and influence the bile salt resistance of GBS by cell wall construction. …”
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504“…We therefore investigated the relative roles of aPBPs and RodA in polar growth using Corynebacterium glutamicum as a model member of Corynebacterineae. …”
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505por Meeske, Alexander J., Riley, Eammon P., Robins, William P., Uehara, Tsuyoshi, Mekelanos, John J., Kahne, Daniel, Walker, Suzanne, Kruse, Andrew C., Bernhardt, Thomas G., Rudner, David Z.“…Cells lacking these enzymes survive by inducing an envelope stress response that increases expression of RodA, a widely conserved core component of the Rod complex. …”
Publicado 2016
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506por Taguchi, Atsushi, Welsh, Michael A., Marmont, Lindsey S., Lee, Wonsik, Sjodt, Megan, Kruse, Andrew C., Kahne, Daniel, Bernhardt, Thomas G., Walker, Suzanne“…Recently, it was shown that RodA, a member of the unrelated SEDS protein family, also acts as a peptidoglycan polymerase.(2–4) Not all bacteria require RodA for growth; however, its homologue, FtsW, is a core member of the divisome complex that appears to be universally essential for septal cell wall assembly.(5,6) FtsW was previously proposed to translocate the peptidoglycan precursor Lipid II across the cytoplasmic membrane.(7,8) We report here that purified FtsW polymerizes Lipid II into peptidoglycan, but show that its polymerase activity requires complex formation with its partner class B PBP (bPBP). …”
Publicado 2019
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507“…Peptidoglycan assembly relies on penicillin-binding proteins (PBPs) acting in concert with SEDS-family transglycosylases RodA and FtsW, which support cell elongation and division respectively. …”
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508por Takacs, Constantin N., Scott, Molly, Chang, Yunjie, Kloos, Zachary A., Irnov, Irnov, Rosa, Patricia A., Liu, Jun, Jacobs-Wagner, Christine“…These results therefore implicate MreB and RodA in the particular mode of cell wall elongation of these bacteria. …”
Publicado 2021
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509“…AfRodA helps Aspergillus fumigatus to evade recognition by the host immune system. RodA-like hydrophobins recruit cutinases to promote the hydrolysis of aliphatic polyesters. …”
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510“…The ΔrodA strain behaved similar to the wild-type strain with or without EphA2 inhibition. …”
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511por Li, Ying, Gong, Han, Zhan, Rui, Ouyang, Shushan, Park, Kyung-Tae, Lutkenhaus, Joe, Du, Shishen“…SEDS family peptidoglycan (PG) glycosyltransferases, RodA and FtsW, require their cognate transpeptidases PBP2 and FtsI (class B penicillin binding proteins) to synthesize PG along the cell cylinder and at the septum, respectively. …”
Publicado 2021
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512por Thywißen, Andreas, Heinekamp, Thorsten, Dahse, Hans-Martin, Schmaler-Ripcke, Jeannette, Nietzsche, Sandor, Zipfel, Peter F., Brakhage, Axel A.“…This is also supported by the observation that pksP conidia still exhibit the RodA hydrophobin layer, as shown by scanning electron microscopy. …”
Publicado 2011
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513por Straume, Daniel, Piechowiak, Katarzyna Wiaroslawa, Olsen, Silje, Stamsås, Gro Anita, Berg, Kari Helene, Kjos, Morten, Heggenhougen, Maria Victoria, Alcorlo, Martín, Hermoso, Juan A., Håvarstein, Leiv Sigve“…Recently, however, it was established that the monofunctional class B PBPs work together with transmembrane glycosyltransferases (FtsW and RodA) from the shape, elongation, division, and sporulation (SEDS) family to make up the core peptidoglycan-synthesizing machineries within the pneumococcal divisome (FtsW/PBP2x) and elongasome (RodA/PBP2b). …”
Publicado 2020
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514por Micelli, Carmina, Dai, Yunfei, Raustad, Nicole, Isberg, Ralph R., Dowson, Christopher G., Lloyd, Adrian J., Geisinger, Edward, Crow, Allister, Roper, David I.“…Exposure to carbapenems or zinc (Zn)-deprived growth conditions leads to a rod-to-sphere morphological transition in A. baumannii, an effect resembling that caused by deficiency in the RodA–PBP2 PG synthesis complex required for cell wall elongation. …”
Publicado 2023
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515por Voltersen, Vera, Blango, Matthew G., Herrmann, Sahra, Schmidt, Franziska, Heinekamp, Thorsten, Strassburger, Maria, Krüger, Thomas, Bacher, Petra, Lother, Jasmin, Weiss, Esther, Hünniger, Kerstin, Liu, Hong, Hortschansky, Peter, Scheffold, Alexander, Löffler, Jürgen, Krappmann, Sven, Nietzsche, Sandor, Kurzai, Oliver, Einsele, Hermann, Kniemeyer, Olaf, Filler, Scott G., Reichard, Utz, Brakhage, Axel A.“…One protein, designated conidial cell wall protein A (CcpA), was identified by both methods and was found to be nearly as abundant as hydrophobic rodlet layer-forming protein RodA. CcpA, an amphiphilic protein, like RodA, peaks in expression during sporulation on resting conidia. …”
Publicado 2018
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516por Shlosman, Irina, Fivenson, Elayne M., Gilman, Morgan S. A., Sisley, Tyler A., Walker, Suzanne, Bernhardt, Thomas G., Kruse, Andrew C., Loparo, Joseph J.“…Here we use single-molecule FRET and cryo-EM to show that an essential PG synthase (RodA-PBP2) responsible for bacterial elongation undergoes dynamic exchange between closed and open states. …”
Publicado 2023
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518“…Our model accurately reproduces the inferred cell growth dynamics and is validated with elongation measurements on a transglycosylase deficient ΔrodA mutant. Finally, with simulations we show that the distribution of cell lengths is narrower for linear than exponential growth, suggesting that this asymptotically linear growth mode can act as a substitute for tight division length and division symmetry regulation.…”
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