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  1. 3421
  2. 3422
  3. 3423
    por Murray, Henry W., Nathan, Carl F.
    Publicado 1999
    “…To determine the relative contributions of respiratory burst–derived reactive oxygen intermediates (ROI) versus reactive nitrogen intermediates (RNI) to macrophage-mediated intracellular host defense, mice genetically deficient in these mechanisms were challenged with Leishmania donovani, a protozoan that selectively parasitizes visceral tissue macrophages. …”
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  4. 3424
    “…These results indicate that (a) the ICSBP/IRF2 complex is essential for IFN-γ–mediated protection against Listeria and that (b) ROI together with additional still unknown effector mechanisms may be responsible for the anti-Listeria activity of macrophages, whereas IRF1-induced RNI are not limiting.…”
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  5. 3425
    “…Finally, a t-test comparison of the slopes of the linear fits of PET versus ASL ΔCBF for all 3 ROI types indicated no significant difference from unity (P > .05).…”
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  6. 3426
  7. 3427
    “…[Image: see text] Bacterial DNA can be damaged by reactive nitrogen and oxygen intermediates (RNI and ROI) generated by host immunity, as well as by antibiotics that trigger bacterial production of ROI. …”
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  8. 3428
  9. 3429
    “…RESULTS: The results of five-year cost-benefit analysis given for 400 Virtual Machines (VMs; i.e., 1,100 users in the case of SNUBH) showed that the break-even point was reached in the fourth year of the investment. At that point, the ROI was 122.6%, the NPV was approximately US$192,000, and the IRR showed an investment validity of 10.8%. …”
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  10. 3430
    “…The mean SI was obtained in the ROI using T1-weighted images. All studies were carried out using a 0.3 T clinical MR scanner with a standard head coil. …”
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  11. 3431
    “…Measures of CBF, in a predetermined set of regions (meta-ROI), and hippocampal volume were compared between CN (n = 47), patients with early and late Mild Cognitive Impairment [EMCI (n = 32), LMCI (n = 35)], and AD (n = 15). …”
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  12. 3432
    “…Analysis of variance (ANOVA) and ROI analysis were also performed. Additionally, source localisation analysis was performed on the EEG data. …”
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  13. 3433
  14. 3434
  15. 3435
    “…Each patient was compared to homotopic cortical regions in 33 healthy controls using region-of-interest (ROI) and vertex-wise analyses. Reduced [(11)C]ABP688 BP(ND) in the FCD was seen in 7/10 patients with combined ROI and vertex-wise analyses. …”
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  16. 3436
    “…A brain region with a significant difference in VMHC was defined as a region of interest (ROI), and the mean VMHC value in the ROI was extracted for the post hoc analysis, i.e., pair-wise comparisons across the three groups. …”
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  17. 3437
    “…The regions of interest (ROI) were set at the cavity-liner (CL) interface and the liner-resin (LR) interface. …”
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  18. 3438
  19. 3439
    “…INTRODUCTION: The quality of data obtained from image analysis can be directly affected by several preanalytical (e.g., staining, image acquisition), analytical (e.g., algorithm, region of interest [ROI]), and postanalytical (e.g., computer processing) variables. …”
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  20. 3440
    “…Total benefits for all households that received EWI were £1,519,045. The ROI of EWI is − 41%. 7.9 years are needed to recoup the costs of the initial investment. …”
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