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221“…A mass univariate analysis revealed that steering selectively diminishes the amplitudes of early P3, late P3, and the re-orientation negativity (RON) to task-irrelevant environmental sounds but not to beep tones. …”
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222por Feng, Liang, Yao, Hang-Ping, Sharma, Sharad, Zhou, Yong-Qing, Zhou, Jianwei, Zhang, Ruiwen, Wang, Ming-HaiEnlace del recurso
Publicado 2016
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223“…The rhoptry neck protein 4 (RON4) forms part of the tight junction, which is essential in the invasion of hepatocytes and/or erythrocytes; however, little is known about this locus’ genetic diversity. …”
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224“…In the immortalized line of human epithelial cells used (BEAS-2B cells), the virus receptor Hyal2 was found to bind to and suppress the activity of RON. When Env was expressed it bound to Hyal2 causing its degradation, release of RON activity from Hyal2 suppression, and activation of pathways resulting in cell transformation. …”
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225por Yadav, Dharmendra K., Kumar, Surendra, Saloni, Misra, Sanjeev, Yadav, Lalit, Teli, Mahesh, Sharma, Praveen, Chaudhary, Sandeep, Kumar, Naresh, Choi, Eun Ha, Kim, Hyung Sik, Kim, Mi-hyun“…Herein, we studied the interaction of thieno[3,2-c]pyran analogs and RONS species with SIRT6 and COX-2 through the use of molecular docking and molecular dynamic simulations. …”
Publicado 2018
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226por Tong, Xiang-Min, Feng, Liang, Suthe, Sreedhar Reddy, Weng, Tian-Hao, Hu, Chen-Yu, Liu, Yi-Zhi, Wu, Zhi-Gang, Wang, Ming-Hai, Yao, Hang-Ping“…RESULTS: H5B14 was highly specific to the human RON PSI domain and superior over other anti-RON ADCs in induction of RON internalization in various cancer cell lines tested. …”
Publicado 2019
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227“…This highly dynamic process is essentially driven by NOX1 and NOS of the tumor cells, and finally leads to intercellular RONS-driven apoptosis induction. This dynamic process can be studied by kinetic analysis, combined with the use of specific inhibitors at defined time intervals. …”
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228por Mosqueda, Juan, Hidalgo-Ruiz, Mario, Calvo-Olvera, Diana Alexandra, Hernandez-Silva, Diego Josimar, Ueti, Massaro Wilson, Mercado-Uriostegui, Miguel Angel, Rodriguez, Angelina, Ramos-Aragon, Juan Alberto, Hernandez-Ortiz, Ruben, Kawazu, Shin-ichiro, Igarashi, Ikuo“…In this work, we found a ron2 gene in the B. bigemina genome. RON2 encodes a protein that is 1351 amino acids long, has an identity of 64% (98% coverage) with RON2 of B. bovis and contains the CLAG domain, a conserved domain in Apicomplexa. …”
Publicado 2019
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229por Hu, Chen-Yu, Xu, Xiang-Ming, Hong, Bo, Wu, Zhi-Gang, Qian, Yun, Weng, Tian-Hao, Liu, Yi-Zhi, Tang, Tao-Ming, Wang, Ming-Hai, Yao, Hang-Ping“…RON (recepteur d'origine nantais) and MET (hepatocyte growth factor receptor) are tyrosine kinase receptors. …”
Publicado 2019
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230por Weng, Tian-Hao, Yao, Min-Ya, Xu, Xiang-Ming, Hu, Chen-Yu, Yao, Shu-Hao, Liu, Yi-Zhi, Wu, Zhi-Gang, Tang, Tao-Ming, Fu, Pei-Fen, Wang, Ming-Hai, Yao, Hang-Ping“…RESULTS: Patients with TNBC had widespread, abnormal expression of RON and MET. There was RON overexpression, MET overexpression, and RON and MET co-overexpression in 63 (33.7%), 63 (33.7%), and 43 cases (23.0%), respectively, which had poor prognosis and short survival. …”
Publicado 2020
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231por Lindfors, Sonja, Polianskyte-Prause, Zydrune, Bouslama, Rim, Lehtonen, Eero, Mannerla, Miia, Nisen, Harry, Tienari, Jukka, Salmenkari, Hanne, Forsgård, Richard, Mirtti, Tuomas, Lehto, Markku, Groop, Per-Henrik, Lehtonen, Sanna“…Here, we investigated the potential anti-inflammatory and renoprotective effects and mechanisms of action of AdipoRon, an adiponectin receptor agonist. METHODS: Wild-type DBA/2J mice were fed with high-fat diet (HFD) supplemented or not with AdipoRon to model obesity-induced metabolic endotoxaemia and chronic low-grade inflammation and we assessed changes in the glomerular morphology and expression of proinflammatory markers. …”
Publicado 2021
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