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Mostrando 121 - 140 Resultados de 8,631 Para Buscar '"Ron"', tiempo de consulta: 0.32s Limitar resultados
  1. 121
    “…Here, we establish a high-throughput screen of randomly mutated minigenes to decode the cis-regulatory landscape that determines alternative splicing of exon 11 in the proto-oncogene MST1R (RON). Mathematical modelling of splicing kinetics enables us to identify more than 1000 mutations affecting RON exon 11 skipping, which corresponds to the pathological isoform RON∆165. …”
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    Decoding a cancer-relevant splicing decision in the RON proto-oncogene using high-throughput mutagenesis
  2. 122
    por Faham, Najme, Zhao, Ling, Welm, Alana L.
    Publicado 2018
    “…Aberrant expression of the RON receptor tyrosine kinase in breast tumors correlates with poor prognosis and has been shown to promote metastasis. …”
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    mTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential
  3. 123
    “…Studying the PTEX-dependent transport of members of the exportome, we discovered that exported proteins, such as ring-infected erythrocyte surface antigen (RESA), failed to be transported in parasites in which the parasite rhoptry protein RON3 was conditionally disrupted. RON3-deficient parasites also failed to develop beyond the ring stage, and glucose uptake was significantly decreased. …”
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    Deletion of Plasmodium falciparum Protein RON3 Affects the Functional Translocation of Exported Proteins and Glucose Uptake
  4. 124
    “…Besides, AdipoRon treatment increased progenitor cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (DG) of diabetic mice. …”
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    Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice
  5. 125
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    Correction: Synthetic adiponectin-receptor agonist, AdipoRon, induces glycolytic dependence in pancreatic cancer cells
  6. 126
    “…The first synthetic orally active adiponectin receptor agonist AdipoRon (AdipoR) has recently been proposed as an anticancer agent in several tumors, including PDAC. …”
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    Integrating Gemcitabine-Based Therapy With AdipoRon Enhances Growth Inhibition in Human PDAC Cell Lines
  7. 127
    “…Sections from paraffin blocks were stained with RON, ROR1 and SUSD2 using immunohistochemistry. …”
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    RON, ROR1 and SUSD2 expression in tissues of endometrial carcinoma patients. Clinicopathological and prognostic implications
  8. 128
    por Fry, Ronald W.
    Publicado 2002
    Libro
    Cómo organizar mejor tu tiempo /
  9. 129
    por Weber, Ron (Ronald)
    Publicado 1988
    Libro
    EDP auditing : conceptual foundations and practice /
  10. 130
    Libro
    El canon científico /
  11. 131
    por Fox, Ron
    Publicado 1980
    Libro
    Medical manual for your home
  12. 132
    por Martinez, Ron
    Publicado 1997
    Libro
    Conversation lessons : the natural language of conversation /
  13. 133
    por Weber, Ron (Ronald)
    Publicado 1982
    Libro
    EDP auditing : conceptual foundations and practice /
  14. 134
    “…Protein processing of full-length RON3 was partially inhibited in the schizont stage, and the RON3 C-terminal fragment was abolished in subsequent ring-stage parasites compared to the RON3 N-terminal fragment. …”
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    Roles of the RON3 C-terminal fragment in erythrocyte invasion and blood-stage parasite proliferation in Plasmodium falciparum
  15. 135
    “…AMA1, a protein secreted from micronemes and associated with the parasite surface during invasion, has been shown in vitro to bind the MJ complex through a direct association with RON2. Here we show that RON2 is inserted as an integral membrane protein in the host cell and, using several interaction assays with native or recombinant proteins, we define the region that binds AMA1. …”
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    The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites
  16. 136
    “…The biological responses of HNSCC cell lines to Ron knockdown, its activation and the biochemical interaction between Ron and EGFR were examined. …”
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    Ron tyrosine kinase receptor synergises with EGFR to confer adverse features in head and neck squamous cell carcinoma
  17. 137
    “…Here, we show that sporoAMA1 and sporoRON2 localize to the apical region of sporozoites and that, in vitro, they interact specifically and exclusively, with no detectable interaction of sporoAMA1 with generic RON2 or sporoRON2 with generic AMA1. …”
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    Toxoplasma gondii Sporozoites Invade Host Cells Using Two Novel Paralogues of RON2 and AMA1
  18. 138
    “…We demonstrate that this inhibition is mediated by the small molecule binding to AMA1 and blocking the formation of AMA1-RON complex. Electron microscopy confirms that the inhibitor prevents junction formation, a critical step in invasion that results from AMA1-RON2 binding. …”
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    Disrupting malaria parasite AMA1 – RON2 interaction with a small molecule prevents erythrocyte invasion
  19. 139
    “…Utilizing early progenitors isolated from NSCLC cell lines and fresh tumor tissues, we observed robust overexpression of PAX8, MET, and RON. PAX8 knockdown A549 cells revealed abrogated PAX8 expression with a concomitant loss in MET and the related RON kinase expression. …”
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    Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer
  20. 140
    “…The Ron receptor is commonly activated in breast cancers, and Ron over-expression in human disease stimulates β-catenin nuclear translocation and is an independent predictor of metastatic dissemination. …”
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    The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor positive breast cancers
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