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1021por van Hoek, M., van Herpt, T. W., Dehghan, A., Hofman, A., Lieverse, A. G., van Duijn, C. M., Witteman, J. C. M., Sijbrands, E. J. G.“…In this population-based study, we investigated whether APOC3 polymorphisms increase type 2 diabetes risk and need for insulin treatment in lean participants. METHODS: In the Rotterdam Study, a population-based prospective cohort (n = 7,983), Cox and logistic regression models were used to analyse the associations and interactive effects of APOC3 promoter variants (−482C > T, −455T > C) and BMI on type 2 diabetes risk and insulin treatment. …”
Publicado 2011
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1022“…METHODS/DESIGN: A cluster randomized controlled trial design, in which we invite all Rotterdam registered inhabitants born in Turkey, aged 16-40 (n = 10,000), to visit the intervention website is used. …”
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1023por Nieuwenhuizen, J., van Ramshorst, G. H., ten Brinke, J. G., de Wit, T., van der Harst, E., Hop, W. C. J., Jeekel, J., Lange, J. F.“…PATIENTS AND METHODS: Correspondence, operation reports and patient files between January 1995 and December 2005 of patients presented at one academic and one teaching hospital in Rotterdam were searched for the following keywords: incarceration, strangulation and hernia. …”
Publicado 2011
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1024por Choté, A. A., Koopmans, G. T., Redekop, W. K., de Groot, C. J. M., Hoefman, R. J., Jaddoe, V. W. V., Hofman, A., Steegers, E. A. P., Mackenbach, J. P., Trappenburg, M., Foets, M.“…The Generation R Study is a multi-ethnic population-based prospective cohort study conducted in the city of Rotterdam. In total, 2,093 pregnant women with a Dutch, Moroccan, Turkish, Cape Verdean, Antillean, Surinamese Creole and Surinamese Hindustani background were included in this study. …”
Publicado 2010
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1025por Güngör, Deniz, de Vries, Juna M, Hop, Wim CJ, Reuser, Arnold JJ, van Doorn, Pieter A, van der Ploeg, Ans T, Hagemans, Marloes LC“…Use of wheelchair and/or respiratory support and patients' score on the Rotterdam Handicap Scale (RHS) were identified as prognostic factors for survival. …”
Publicado 2011
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1026“…A total of 216 eligible outpatients are randomised using pre-randomisation double-consent design and receive either 12 weeks treatment with oral topiramate (n = 36; Brijder Addiction Treatment, The Hague), oral modafinil (n = 36; Arkin, Amsterdam), or oral dexamphetamine sustained-release (n = 36; Bouman GGZ, Rotterdam) as an add-on to cognitive behavioural therapy (CBT), or receive a 12-week CBT only (controls: n = 3 × 36). …”
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1027por Deelen, Joris, Beekman, Marian, Uh, Hae-Won, Helmer, Quinta, Kuningas, Maris, Christiansen, Lene, Kremer, Dennis, van der Breggen, Ruud, Suchiman, H Eka D, Lakenberg, Nico, van den Akker, Erik B, Passtoors, Willemijn M, Tiemeier, Henning, van Heemst, Diana, de Craen, Anton J, Rivadeneira, Fernando, de Geus, Eco J, Perola, Markus, van der Ouderaa, Frans J, Gunn, David A, Boomsma, Dorret I, Uitterlinden, André G, Christensen, Kaare, van Duijn, Cornelia M, Heijmans, Bastiaan T, Houwing-Duistermaat, Jeanine J, Westendorp, Rudi G J, Slagboom, P Eline“…The strongest candidate SNPs from this GWAS have been analyzed in a meta-analysis of nonagenarian cases from the Rotterdam Study, Leiden 85-plus study, and Danish 1905 cohort. …”
Publicado 2011
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1028“…Motor assessments included: grip and tripod pinch strength using a digital grip analyser (MIE), manual muscle testing of abductor pollicis brevis and opponens pollicis using the Rotterdam Intrinsic Handheld Myometer (RIHM). The Boston Carpal Tunnel Questionnaire (BCTQ) was used as a patient rated outcome measure. …”
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1029por Ganie, Mohd Ashraf, Farooqui, Khalid Jamal, Bhat, Mohd Ashraf, Mir, Mohammad Muzzafar, Shah, Zaffar Amin, Douhath, Syed, Mir, Syed Hussain, Rashid, Fouzia, Naqshi, Shazia, Masoodi, Mohd Ibrahim, Zargar, S. A., Zargar, Abdul Hamid“…The diagnosis of PCOS was made according to the Rotterdam criteria. Blood samples were collected in the follicular phase of the menstrual cycle and analyzed for fasting luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), 17-hydroxyprogesterone (17-OHP), total testosterone (T), glucose, insulin, and lipid profile. …”
Publicado 2012
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1030por Silva, Lindsay M., van Rossem, Lenie, Jansen, Pauline W., Hokken-Koelega, Anita C. S., Moll, Henriëtte A., Hofman, Albert, Mackenbach, Johan P., Jaddoe, Vincent W. V., Raat, Hein“…METHODS: This study was based on data from 2972 mothers with a Dutch ethnicity, and their children participating in The Generation R Study, a population-based cohort study in Rotterdam, the Netherlands (participation rate 61%). …”
Publicado 2012
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1031por Been, Jasper V., Vanterpool, Sizzle F., de Rooij, Jasmijn D. E., Rours, G. Ingrid J. G., Kornelisse, René F., van Dongen, Martien C. J. M., van Gool, Christel J. A. W., de Krijger, Ronald R., Andriessen, Peter, Zimmermann, Luc J. I., Kramer, Boris W.“…METHODS: Clinical data and placental pathology were obtained from singleton preterm newborns (gestational age ≤32.0 weeks) born at Erasmus UMC Rotterdam from 2001 to 2003 (derivation cohort; n = 216) or Máxima MC Veldhoven from 2009 to 2010 (validation cohort; n = 206). …”
Publicado 2012
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1032por Siggelkow, Wulf, Boehm, Daniel, Gebhard, Susanne, Battista, Marco, Sicking, Isabel, Lebrecht, Antje, Solbach, Christine, Hellwig, Birte, Rahnenführer, Jörg, Koelbl, Heinz, Gehrmann, Mathias, Marchan, Rosemarie, Cadenas, Cristina, Hengstler, Jan G, Schmidt, Marcus“…RESULTS: Patients with higher AURKA expression had a shorter metastasis-free survival (MFS) in the Mainz (HR 1.93; 95% CI 1.34 – 2.78; P < 0.001), Rotterdam (HR 1.95; 95% CI 1.45– 2.63; P<0.001) and Transbig (HR 1.52; 95% CI 1.14–2.04; P=0.005) cohorts. …”
Publicado 2012
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1033por Sinha, Uma, Sinharay, Keshab, Saha, Sudipta, Longkumer, T. Amenla, Baul, Shuvra Neel, Pal, Salil Kuamr“…MATERIALS AND METHODS: This prospective single-center study recruited 106 female patients with hypertrichosis and menstrual abnormality among which 80 patients were defined as having PCOS according to the revised 2003 Rotterdam criteria and comprised the study population. …”
Publicado 2013
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1034por Broer, L., Demerath, E. W., Garcia, M. E., Homuth, G., Kaplan, R. C., Lunetta, K. L., Tanaka, T., Tranah, G. J., Walter, S., Arnold, A. M., Atzmon, G., Harris, T. B., Hoffmann, W., Karasik, D., Kiel, D. P., Kocher, T., Launer, L. J., Lohman, K. K., Rotter, J. I., Tiemeier, H., Uitterlinden, A. G., Wallaschofski, H., Bandinelli, S., Dörr, M., Ferrucci, L., Franceschini, N., Gudnason, V., Hofman, A., Liu, Y., Murabito, J. M., Newman, A. B., Oostra, B. A., Psaty, B. M., Smith, A. V., van Duijn, C. M.“…Our discovery cohort was the Rotterdam study (RS1) containing 5,974 participants aged 55 years and older (3,174 deaths). …”
Publicado 2012
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1035por Flink, Ilse J. E., Prins, Rick G., Mackenbach, Johan J. P., Jaddoe, Vincent W., Hofman, Albert, Verhulst, Frank C., Tiemeier, Henning, Raat, Hein“…METHODS: We included 3076 preschoolers participating in the Generation R Study, a birth cohort study in Rotterdam, the Netherlands. At child age 3-years, parents completed the Child Behavior Checklist (CBCL/1,5-5). …”
Publicado 2013
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1036Androgen Receptor CAG Repeats Length Polymorphism and the Risk of Polycystic Ovarian Syndrome (PCOS)por Rajender, Singh, Carlus, Silas Justin, Bansal, Sandeep Kumar, Negi, Mahendra Pratap Singh, Sadasivam, Nirmala, Sadasivam, Muthusamy Narayanan, Thangaraj, Kumarasamy“…METHODS: CAG repeat region of 169 patients recruited following strictly defined Rotterdam (2003) inclusion criteria and that of 175 ethnically similar control samples, were analyzed. …”
Publicado 2013
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1037por Hafkamp-de Groen, Esther, van der Valk, Ralf J. P., Mohangoo, Ashna D., van der Wouden, Johannes C., Duijts, Liesbeth, Jaddoe, Vincent W., Hofman, Albert, de Koning, Harry J., de Jongste, Johan C., Raat, Hein“…METHODS: Sixteen well-child centres in Rotterdam, the Netherlands, were randomised into 8 centres where the brief assessment form regarding asthma-like symptoms and ETS exposure was used and 8 centres that applied usual care. 3596 and 4179 children (born between April 2002 and January 2006) and their parents visited the intervention and control centres, respectively. …”
Publicado 2014
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1038por O'Reilly, Michael W., Taylor, Angela E., Crabtree, Nicola J., Hughes, Beverly A., Capper, Farfia, Crowley, Rachel K., Stewart, Paul M., Tomlinson, Jeremy W., Arlt, Wiebke“…PATIENTS AND METHODS: Eighty-six PCOS patients fulfilling Rotterdam diagnostic consensus criteria and 43 age- and body mass index-matched controls underwent measurement of serum androgens by tandem mass spectrometry and an oral glucose tolerance test with homeostatic model assessment of insulin resistance and insulin sensitivity index calculation. …”
Publicado 2014
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1039por Ramanand, Sunita J., Ramanand, Jaiprakash B., Ghongane, Balasaheb B., Patwardhan, Milind H., Patwardhan, Varsha M., Ghanghas, Ravi, Halasawadekar, Nimish R., Patil, Praveenkumar“…MATERIALS AND METHODS: A prospective study in 49 newly diagnosed (as per Rotterdam criteria) Indian PCOS women was conducted. …”
Publicado 2014
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1040por Duvvari, Maheswara R., Paun, Codrut C., Buitendijk, Gabriëlle H. S., Saksens, Nicole T. M., Volokhina, Elena B., Ristau, Tina, Schoenmaker-Koller, Frederieke E., van de Ven, Johannes P. H., Groenewoud, Joannes M. M., van den Heuvel, Lambertus P. W. J., Hofman, Albert, Fauser, Sascha, Uitterlinden, André G., Klaver, Caroline C. W., Hoyng, Carel B., de Jong, Eiko K., den Hollander, Anneke I.“…However, the Arg735Trp and Ser1619Arg variants were not found to be associated with AMD in the Rotterdam Study. The Lys65Gln variant was only identified in patients from Nijmegen, the Netherlands, and thus may represent a region-specific AMD risk variant.…”
Publicado 2014
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