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801“…Here, we explored the role of microglia in the Royal College of Surgeons (RCS) rat model of mutMerTK-RP. We found elevated levels of inflammatory cytokines and CD68 microglia activation marker, and more ionized calcium-binding adapter molecule 1 (Iba-1) positive microglia in RCS retina when compared to wild-type retina as early as postnatal day 14 (P14). …”
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802por Maya-Vetencourt, José Fernando, Di Marco, Stefano, Mete, Maurizio, Di Paolo, Mattia, Ventrella, Domenico, Barone, Francesca, Elmi, Alberto, Manfredi, Giovanni, Desii, Andrea, Sannita, Walter G., Bisti, Silvia, Lanzani, Guglielmo, Pertile, Grazia, Bacci, Maria Laura, Benfenati, Fabio“…Conjugated polymers represent an attractive solution to the field of retinal prostheses, and a multi-layer fully organic prosthesis implanted subretinally in dystrophic Royal College of Surgeons (RCS) rats was able to rescue visual functions. …”
Publicado 2020
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803por Pennington, Britney O., Bailey, Jeffrey K., Faynus, Mohamed A., Hinman, Cassidy, Hee, Mitchell N., Ritts, Rory, Nadar, Vignesh, Zhu, Danhong, Mitra, Debbie, Martinez-Camarillo, Juan Carlos, Lin, Tai-Chi, Thomas, Biju B., Hinton, David R., Humayun, Mark S., Lebkowski, Jane, Johnson, Lincoln V., Clegg, Dennis O.“…REPS were administered immediately post-thaw into the subretinal space of a mammalian model, the Royal College of Surgeons (RCS)/nude rat. Implanted REPS were assessed at 30, 60, and 90 days post-implantation, and thawed cells demonstrate survival as an intact monolayer on the parylene scaffold. …”
Publicado 2021
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804por Park, Un Chul, Park, Susanna S., Kim, Bo Hee, Park, Sung Wook, Kim, Young Joo, Cary, Whitney, Anderson, Johnathon D., Nolta, Jan A., Yu, Hyeong Gon“…Exosomes were harvested from cultured human MSCs under hypoxic conditions. Royal College of Surgeons (RCS) 3-weeks-old rats, immunosuppressed with cyclosporine A, received subretinal or intravitreal injection of CD34+ cells (50,000 cells), CD34+ cells with exosomes (50,000 cells+10 µg), exosomes alone (10 µg), or PBS. …”
Publicado 2021
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805“…After the S-UCMSCs and UCMSCs were intravenously infused into the Royal College of Surgeons (RCS) rats at a dose of 1 × 10(6) cells/rat, the S-UCMSCs blocked in the lungs were significantly fewer and disappeared more quickly than UCMSCs. …”
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806por Kovoor, Joshua G., Layton, Georgia R., Burke, Joshua R., Churchill, James A., Jacobsen, Jonathan Henry W., Reid, Jessica L., Edwards, Suzanne, Issa, Eyad, Garrod, Tamsin J., Archer, Julian, Tivey, David R., Babidge, Wendy J., Dennison, Ashley R., Maddern, Guy J.“…METHOD: Trainees across Australia, New Zealand and UK enrolled in surgical training accredited by the Royal Australasian College of Surgeons or Royal College of Surgeons were included. Outcomes included the short version of the Perceived Stress Scale, Oxford Happiness Questionnaire short scale, Patient Health Questionnaire‐2 and the effect on individual stress levels of training experiences affected by COVID‐19. …”
Publicado 2022
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807“…METHOD: Twenty-three revision TKA scenarios were assigned priority (NHS England/Royal College of Surgeons scale) by the British Association for Surgery of the Knee (BASK) Revision Knee Working Group (n = 24). …”
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808“…OBJECTIVES: The Royal College of Surgeons of England (RCS) Good Surgical Practice guidance identifies essential criteria for surgical operation note documentation. …”
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809“…Course content is mapped to the Royal College of Surgeons’ Undergraduate Curriculum in Surgery. …”
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810por Perera, Hector, Wusu, Adedoyin M, Mohammad, Alhashash, Qulaghassi, Mahdi Z, Adekola, Adekunle, Rao, Madhu“…The General Medical Council (GMC) and the Royal College of Surgeons of England (RCS) provide guidance on what constitutes valid consent. …”
Publicado 2023
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811“…PURPOSE: Previously, studies showed that subretinal electrical stimulation (SES) from a microphotodiode array (MPA) preserves electroretinography (ERG) b-wave amplitude and regional retinal structure in the Royal College of Surgeons (RCS) rat and simultaneously upregulates Fgf2 expression. …”
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812por Evans, Jonathan T, Walker, Robert W, Evans, Jonathan P, Blom, Ashley W, Sayers, Adrian, Whitehouse, Michael R“…FUNDING: The National Joint Registry for England, Wales, Northern Ireland, and Isle of Man and the Royal College of Surgeons of England.…”
Publicado 2019
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813por Price, Stephen John, Joannides, Alexis, Plaha, Puneet, Afshari, Fardad Taghizadeh, Albanese, Erminia, Barua, Neil U, Chan, Huan Wee, Critchley, Giles, Flannery, Thomas, Fountain, Daniel M, Mathew, Ryan K, Piper, Rory J, Poon, Michael TC, Rajaraman, Chittoor, Rominiyi, Ola, Smith, Stuart, Solomou, Georgios, Solth, Anna, Surash, Surash, Wykes, Victoria, Watts, Colin, Bulbeck, Helen, Hutchinson, Peter, Jenkinson, Michael D“…STUDY REGISTRATION: This study was registered with the Royal College of Surgeons of England’s COVID-19 Research Group (https://www.rcseng.ac.uk/coronavirus/rcs-covid-research-group/).…”
Publicado 2020
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814por Zhang, Hang, Su, Bingnan, Jiao, Luyan, Xu, Ze-Hua, Zhang, Chang-Jun, Nie, Jinfu, Gao, Mei-Ling, Zhang, Ying V., Jin, Zi-Bing“…Transplantation of iRPE has been proven effective in rescuing impaired retinas in Royal College of Surgeons (RCS) rats after approximately 5 to 6 weeks. …”
Publicado 2021
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815por Eckhardt, Charlotte E., Seehra, Jadbinder, Chadwick, Stephen M., Voerman, Kim, Landau, Alex, Ryan, Fiona S., Fleming, Padhraig S., Garrett, Matthew, Cobourne, Martyn T.“…Introduction The Royal College of Surgeons of England (RCSEng) and the Royal College of Physicians and Surgeons of Glasgow (RCPSG) offer the bi-collegiate Membership in Orthodontics (MOrth) examination, a summative assessment of specialist knowledge, skill and behaviour in orthodontics. …”
Publicado 2021
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816por Hamm, Gregory, Maglennon, Gareth, Williamson, Beth, Macdonald, Ruth, Doherty, Ann, Jones, Stewart, Harris, Jayne, Blades, James, Harmer, Alexander R., Barton, Peter, Rawlins, Philip B., Smith, Paul, Winter-Holt, Jon, McMurray, Lindsay, Johansson, Julia, Fitzpatrick, Paul, McCoull, William, Coen, Muireann“…The receptor tyrosine kinase, MERTK, plays an essential role in homeostasis of the retina via efferocytosis of shed outer nuclear segments of photoreceptors. The Royal College of Surgeons rat model of retinal degeneration has been linked to loss-of-function of MERTK, and together with the MERTK knock-out mouse, phenocopy retinitis pigmentosa in humans with MERTK mutations. …”
Publicado 2022
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817por Lu, Bin, Avalos, Pablo, Svendsen, Soshana, Zhang, Changqing, Nocito, Laura, Jones, Melissa K., Pieplow, Cosmo, Saylor, Joshua, Ghiam, Sean, Block, Amanda, Fernandez, Michael, Ljubimov, Alexander V., Small, Kent, Liao, David, Svendsen, Clive N., Wang, Shaomei“…METHODS: Research-grade human neural progenitor cells (hNPC) and clinical-grade hNPC (termed CNS10-NPC) were injected into the subretinal space of the Royal College of Surgeons (RCS) rat, a rodent model of retinal degeneration such as retinitis pigmentosa. …”
Publicado 2023
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818Publicado 2023“…SPEAKERS/PANELISTS: Thom Geertsema Groningen Center Health Law, Faculty of Law, University of Groningen, Groningen, Netherlands Ben Cave Ben Cave Associates Ltd, Leeds, UK Mary Rose Sweeney Faculty of Nursing and Midwifery, Royal College of Surgeons in Ireland, Dublin, Ireland Desislava Vankova Medical University of Varna, Varna, Bulgaria Nikhil Gokani University of Essex, Colchester, UK…”
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819por Lane, Jennifer C E, Craig, Richard S, Rees, Jonathan L, Gardiner, Matthew D, Green, Jane, Prieto-Alhambra, Daniel, Furniss, Dominic“…FUNDING: Versus Arthritis; Medical Research Council; Royal College of Surgeons of England and National Joint Registry research fellowship; University of Oxford; National Institute for Health Research; and National Institute for Health Research Biomedical Research Centre, Oxford.…”
Publicado 2020
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820por Abuzeyad, Feras H., Al Qasem, Leena, Bashmi, Luma, Arekat, Mona, Al Qassim, Ghada, Alansari, Ahmed, Haji, Eman Ahmed, Malik, Amena, Das, Priya, Almusalam, Abdulla, Abuzeyad, Maryam Feras“…METHODS: Data were collected from the Bahraini Ministry of Health, National Health Regulatory Authority, Salmaniya Medical Complex, King Hamad University Hospital, Bahrain Defence Force Royal Medical Services, the College of Medicine and Medical Sciences in the Arabian Gulf University, and the Royal College of Surgeons in Ireland-Bahrain. Only physicians who held a Bachelor of Medicine and Surgery and a valid license to practice from NHRA were eligible to participate. …”
Publicado 2022
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