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  1. 12401
    “…The S(C32) is located far from arsenic in the WT-hAS3MT-SAM-As model. The distances between S(C61) and arsenic in WT-hAS3MT-As and WT-hAS3MT-SAM-As models are 7.5 Å and 4.1 Å, respectively. …”
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    Identification of the Third Binding Site of Arsenic in Human Arsenic (III) Methyltransferase
  2. 12402
    “…Background: Diarrhea affects a large proportion of children with severe acute malnutrition (SAM). However, its etiology and clinical consequences remain unclear. …”
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    Mortality in children with complicated severe acute malnutrition is related to intestinal and systemic inflammation: an observational cohort study(1)(2)
  3. 12403
    “…BACKGROUND: Acute malnutrition is currently divided into severe (SAM) and moderate (MAM) based on level of wasting. …”
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    The "ComPAS Trial" combined treatment model for acute malnutrition: study protocol for the economic evaluation
  4. 12404
    “…RESULT: Of 494 children with SAM, 410 were discharged and 379 were followed up. …”
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    Survival and nutritional status of children with severe acute malnutrition, six months post-discharge from outpatient treatment in Jigawa state, Nigeria
  5. 12405
    “…Our simulation study also shows that the LR-SAM approach performs similarly well as LMM approaches, in most cases. …”
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    Analysis of significant protein abundance from multiple reaction-monitoring data
  6. 12406
    “…Inhibition by the SAM analog sinefungin was competitive with respect to SAM (K(i) = 0.41 ± 0.07 µM) and uncompetitive for tRNA (K(i) = 6.4 ± 0.8 µM). …”
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    Crystal structure and catalytic mechanism of the essential m(1)G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa
  7. 12407
    “…GtmA converts DTG to bisdethiobis(methylthio)gliotoxin (BmGT), using 2 mol SAM and resultant SAH must be re-converted to SAM via the action of the Methyl/Met cycle. …”
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    Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic Implications
  8. 12408
    “…BACKGROUND: Severe acute malnutrition (SAM) affects about 13 million under-five children (U5), with an estimated one million dying every year. …”
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    Predictors of in-hospital mortality among under-five children with severe acute malnutrition in South-Western Uganda
  9. 12409
    “…The production of SAM is promoted by the folate cycle. Knockdown of MTHFD2 and MTHFR, two key enzymes in folate metabolism and methyl donor SAM production, significantly suppressed GC cell proliferation. …”
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    MiR-22, regulated by MeCP2, suppresses gastric cancer cell proliferation by inducing a deficiency in endogenous S-adenosylmethionine
  10. 12410
    “…Metabolic parameters, like SUV(max), SAM, normalized SAM (NSAM) and TLG were assessed by FDG-PET/CT, carried out at baseline (scan-1) and after two therapeutic cycle (scan-2). …”
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    Metabolic Parameters as Predictors for Progression Free and Overall Survival of Patients with Metastatic Colorectal Cancer
  11. 12411
    “…Health system constraints hamper treatment of children with severe acute malnutrition (SAM) in Tanzania. This non-inferiority quasi-experimental study in Bariadi (intervention) and Maswa (control) districts assessed the effectiveness, coverage, and cost-effectiveness of SAM treatment by community health workers (CHWs) compared with outpatient therapeutic care (OTC). …”
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    Effectiveness of screening and treatment of children with severe acute malnutrition by community health workers in Simiyu region, Tanzania: a quasi-experimental pilot study
  12. 12412
    “…Social accounting matrix (SAM) is an established framework that evaluates public policies with multiple perspectives that could help. …”
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    Comparing the Analysis and Results of a Modified Social Accounting Matrix Framework with Conventional Methods of Reporting Indirect Non-Medical Costs
  13. 12413
    “…BACKGROUND: Children hospitalized with severe acute malnutrition (SAM) have poor long-term outcomes following discharge, with high rates of mortality, morbidity, and impaired neurodevelopment. …”
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    Postdischarge interventions for children hospitalized with severe acute malnutrition: a systematic review and meta-analysis
  14. 12414
    “…The proportion of receiving ciprofloxacin was significantly lower in infants with SAM compared to their non‐SAM counterparts (2.7% vs. 7.97%, P value = 0.004). …”
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    Antibiotic exposure among young infants suffering from diarrhoea in Bangladesh
  15. 12415
    “…BACKGROUND: A combination of the antipsychotic olanzapine and opioid receptor antagonist samidorphan (OLZ/SAM) is in development for the treatment of patients with schizophrenia or bipolar I disorder. …”
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    Application of Physiologically Based Pharmacokinetic Modeling to Predict the Effect of Renal Impairment on the Pharmacokinetics of Olanzapine and Samidorphan Given in Combination
  16. 12416
    “…Ready-to-use therapeutic food (RUTF) with adequate quality protein is used to treat children with oedematous and non-oedematous severe acute malnutrition (SAM). The plasma amino acid (AA) profile reflects the protein nutritional status; hence, its assessment during SAM treatment is useful in evaluating AA delivery from RUTFs. …”
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    Amino acid-enriched plant-based RUTF treatment was not inferior to peanut-milk RUTF treatment in restoring plasma amino acid levels among patients with oedematous or non-oedematous malnutrition
  17. 12417
    “…BACKGROUND: Children with severe acute malnutrition (SAM) who require nutritional rehabilitation unit (NRU) treatment often have poor developmental and nutritional outcomes following discharge. …”
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    A Mixed-Methods Cluster-Randomized Controlled Trial of a Hospital-Based Psychosocial Stimulation and Counseling Program for Caregivers and Children with Severe Acute Malnutrition
  18. 12418
    “…As a part of this operon, the urf7 gene encodes SAM-dependent methyltransferase. As a consequence of these findings, it is reasonable to propose that the hypothetical protein of interest in this study is a SAM-dependent methyltransferase associated with bacterial NADH-ubiquinone oxidoreductase assembly. …”
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    In Silico Identification and Characterization of a Hypothetical Protein From Rhodobacter capsulatus Revealing S-Adenosylmethionine-Dependent Methyltransferase Activity
  19. 12419
    “…The homologous prime-boost vaccination regimen of SAM at 3, 10 and 30 μg induced potent neutralizing antibody (nAb) titers in rhesus macaques following two SAM vaccinations at all dose levels, with the 10 μg dose generating geometric mean titers (GMT) 48-fold greater than the GMT of a panel of SARS-CoV-2 convalescent human sera. …”
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    Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection
  20. 12420
    “…Of the infants with SAM, 14 (53.85%) had secretor mothers, and 11 (57.89%) of the non-malnourished infants had secretor mothers. …”
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    Association of human milk oligosaccharides and nutritional status of young infants among Bangladeshi mother–infant dyads
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