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  1. 12461
    “…Background The WHO protocol for the management of shock in children with severe acute malnutrition (SAM) is not supported by physiological evidence. …”
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    Effectiveness of the WHO Protocol for the Management of Shock in Children With Severe Acute Malnutrition
  2. 12462
    “…Cells lacking Met4p grow normally when either SAM is added to the media or one of the SAM synthetase genes is overexpressed. …”
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    Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast
  3. 12463
    por Cobb, G, Bland, R M
    Publicado 2013
    “…Additionally, 25 children had SAM and required 10-weeks NCP-C followed by 16-weeks NCP-B. …”
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    Nutritional supplementation: the additional costs of managing children infected with HIV in resource-constrained settings
  4. 12464
    “…Restriction enzyme (REase) RM.BpuSI can be described as a Type IIS/C/G REase for its cleavage site outside of the recognition sequence (Type IIS), bifunctional polypeptide possessing both methyltransferase (MTase) and endonuclease activities (Type IIC) and endonuclease activity stimulated by S-adenosyl-L-methionine (SAM) (Type IIG). The stimulatory effect of SAM on cleavage activity presents a major paradox: a co-factor of the MTase activity that renders the substrate unsusceptible to cleavage enhances the cleavage activity. …”
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    The Role of the Methyltransferase Domain of Bifunctional Restriction Enzyme RM.BpuSI in Cleavage Activity
  5. 12465
    “…METHODS: Suitability assessment of materials (SAM) and readability tests were run by three independent evaluators on 46 PAs (14 “Pre-format change” and 32 “Post-format change”). …”
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    Evaluating the Health Literacy Burden of Canada’s Public Advisories: A Comparative Effectiveness Study on Clarity and Readability
  6. 12466
    “…Hcy, cysteine, glutathione (GSH), S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), folate and cobalamin concentrations were measured in the plasma and/or brain. …”
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    Effect of Vitamin B Deprivation during Pregnancy and Lactation on Homocysteine Metabolism and Related Metabolites in Brain and Plasma of Mice Offspring
  7. 12467
    “…Here we solve crystal structure of NleE-SAM complex, which reveals a methyltransferase fold different from those of known ones. …”
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    Structure and Specificity of the Bacterial Cysteine Methyltransferase Effector NleE Suggests a Novel Substrate in Human DNA Repair Pathway
  8. 12468
    “…The maintenance of shoot apical meristem (SAM) identity, miRNAs and flowering integrators are involved in this phase change process. …”
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    Rice osa-miR171c Mediates Phase Change from Vegetative to Reproductive Development and Shoot Apical Meristem Maintenance by Repressing Four OsHAM Transcription Factors
  9. 12469
    “…Our results demonstrated that the SAM rats experienced brain cell death in the ischemic core. …”
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    Global Proteomic Analysis of Brain Tissues in Transient Ischemia Brain Damage in Rats
  10. 12470
    “…Here we used ultra-high pressure liquid chromatography coupled to an electrospray ionization source and a triple-quadrupole mass spectrometer [UHPLC-ESI-QqQ-MS/MS] to quantitatively examine the methionine/folate bi-cyclic 1C metabolome during nuclear reprogramming of somatic cells into iPS cells. iPS cells optimize the synthesis of the universal methyl donor S-adenosylmethionine (SAM), apparently augment the ability of the redox balance regulator NADPH in SAM biosynthesis, and greatly increase their methylation potential by triggering a high SAM:S-adenosylhomocysteine (SAH) ratio. …”
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    Activation of the methylation cycle in cells reprogrammed into a stem cell-like state
  11. 12471
    “…The South Asian Monson (SAM) is one of the most intense climatic elements yet its initiation and variations are not well established. …”
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    The abrupt onset of the modern South Asian Monsoon winds
  12. 12472
    “…Consistently, CRISPR/dCas9 VP64 with SAM upregulated REPRIMO (680-fold change), which led to phenotypic reprogramming in AGS gastric cancer cells. …”
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    Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system
  13. 12473
    “…To reach this goal, we established suspension-adhesion method (SAM) and three-dimensional (3D) suspension method (3DSM). …”
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    Efficient feeder cells preparation system for large-scale preparation and application of induced pluripotent stem cells
  14. 12474
    “…PqqE is a radical S‐adenosyl‐l‐methionine (SAM) enzyme that catalyzes the initial reaction of pyrroloquinoline quinone (PQQ) biosynthesis. …”
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    Characterization of auxiliary iron–sulfur clusters in a radical S‐adenosylmethionine enzyme PqqE from Methylobacterium extorquens AM1
  15. 12475
    “…Phosphatidylcholines (PC) and S-adenosylmethionine (SAM) are critical determinants of hepatic lipid levels, but how their levels are regulated is unclear. …”
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    AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
  16. 12476
    “…This study assessed recovery from severe acute malnutrition (SAM), fatality, and acute malnutrition up to 14 weeks after admission to a programme integrated in the primary health care system. …”
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    An integrated community‐based outpatient therapeutic feeding programme for severe acute malnutrition in rural Southern Ethiopia: Recovery, fatality, and nutritional status after discharge
  17. 12477
    “…NifB is an essential radical S-adenosylmethionine (SAM) enzyme for nitrogenase cofactor assembly. Previous studies show that NifB couples a putative pair of [Fe(4)S(4)] modules (designated K1 and K2) into an [Fe(8)S(9)C] cofactor precursor concomitant with radical SAM-dependent carbide insertion through the action of its SAM-binding [Fe(4)S(4)] module. …”
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    Probing the coordination and function of Fe(4)S(4) modules in nitrogenase assembly protein NifB
  18. 12478
    “…The objectives of most treatment programs for severe acute malnutrition (SAM) in children focus on initial recovery only, leaving post‐discharge outcomes, such as relapse, poorly understood and undefined. …”
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    Relapse after severe acute malnutrition: A systematic literature review and secondary data analysis
  19. 12479
    “…The activated methyl cycle (AMC) is responsible for the generation of S-adenosylmethionine (SAM), which is a substrate of N-acylhomoserine lactone (AHL) synthases. …”
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    Unraveling the role of quorum sensing-dependent metabolic homeostasis of the activated methyl cycle in a cooperative population of Burkholderia glumae
  20. 12480
    “…Observational records show that occurrences of the negative polarity of the Southern Annular Mode (low SAM) is significantly linked to El Niño during austral spring and summer, potentially providing long-lead predictability of the SAM and its associated surface climate conditions. …”
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    Continuation of tropical Pacific Ocean temperature trend may weaken extreme El Niño and its linkage to the Southern Annular Mode
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