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12881por Subramanian, Sathish, Huq, Sayeeda, Yatsunenko, Tanya, Haque, Rashidul, Mahfuz, Mustafa, Alam, Mohammed A., Benezra, Amber, DeStefano, Joseph, Meier, Martin F., Muegge, Brian D., Barratt, Michael J., VanArendonk, Laura G., Zhang, Qunyuan, Province, Michael A., Petri, William A., Ahmed, Tahmeed, Gordon, Jeffrey I.“…Therapeutic food interventions have reduced mortality in children with severe acute malnutrition (SAM) but incomplete restoration of healthy growth remains a major problem(1,2). …”
Publicado 2014
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12882por Zhou, Yun, Liu, Xing, Engstrom, Eric M., Nimchuk, Zachary L., Pruneda-Paz, Jose L., Tarr, Paul T., Yan, An, Kay, Steve A., Meyerowitz, Elliot M.“…WUSCHEL (WUS), a homeodomain transcription factor expressed in the rib meristem of the SAM, is a key regulatory factor controlling stem cell populations in the Arabidopsis SAM(5–6) and is thought to establish the shoot stem cell niche via a feedback circuit with the CLAVATA3 (CLV3) peptide signaling pathway(7). …”
Publicado 2014
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12883por Blackwell, Nikki, Myatt, Mark, Allafort-Duverger, Thierry, Balogoun, Amour, Ibrahim, Almou, Briend, André“…RESULTS: Mothers’ had a sensitivity and specificity for classification of their child’s nutritional status of > 90% and > 80% respectively for global acute malnutrition (GAM, defined by a MUAC < 125 mm) and > 73% and > 98% for severe acute malnutrition (SAM, defined by a MUAC < 115 mm). The few children misclassified as not having SAM, were classified as having moderate acute malnutrition (MAM). …”
Publicado 2015
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12884por Cortez, Sarah, Milbrandt, Melissa, Kaphingst, Kimberly, James, Aimee, Colditz, Graham“…The primary outcomes are the frequency distribution of overall SAM readability category (superior, adequate, or not suitable) and mean SMOG reading grade level. …”
Publicado 2015
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12885por Chen, Hui, Liu, Shuai, Ji, Lu, Wu, Tianfeng, Ji, Yong, Zhou, Yuying, Zheng, Miaoyan, Zhang, Meilin, Xu, Weili, Huang, Guowei“…The mean MMSE was slightly increased in the intervention group compared to that in the control group (P < 0.05). Posttreatment, plasma SAM and SAM/SAH levels were significantly higher (P < 0.05), while Aβ (40), PS1-mRNA, and TNFα-mRNA levels were lower in the intervention group than in the control group (P < 0.05). …”
Publicado 2016
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12886por Kuć, Mateusz, Kołsut, Piotr, Różański, Jacek, Dąbrowski, Maciej, Kłopotowski, Mariusz, Kumor, Magda, Kowalski, Mirosław, Kopyłowska, Natalia, Kuriata, Jarosław, Kuśmierczyk, Mariusz“…No significant correlation was observed between residual SAM and the grade of mitral regurgitation (p = 0.699) or between residual SAM and the LVOT gradient (p = 0.280). …”
Publicado 2016
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12887“…SAM and TUB exhibited stable expression in heat-treated leaves. …”
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12888por Shepherd, John A., Ng, Bennett K., Fan, Bo, Schwartz, Ann V., Cawthon, Peggy, Cummings, Steven R., Kritchevsky, Stephen, Nevitt, Michael, Santanasto, Adam, Cootes, Timothy F.“…Three parameters from a SAM of only body thickness predicted mortality (training AUC = 0.66, validation AUC = 0.62). …”
Publicado 2017
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12889“…In the absence of RTA, the highest ELP Ni-P film adhesion occurs when ETAS modification approaches SAM, where insufficient or multi-layer ETAS grafting fails to provide satisfactory results. …”
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12890“…When sufficient sample replicates were available, SAM and our methods showed similar performance. …”
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12891por Daniel, Allison I., van den Heuvel, Meta, Voskuijl, Wieger P., Gladstone, Melissa, Bwanali, Mike, Potani, Isabel, Bourdon, Celine, Njirammadzi, Jenala, Bandsma, Robert H. J.“…BACKGROUND: Severe acute malnutrition (SAM) is associated with high mortality rates and impairments in growth and development in children that do survive. …”
Publicado 2017
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12892“…We retrospectively analysed files of 254 children with SAM aged 6–59 months admitted from April 2015 to August 2016. …”
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12893por Wang, Qianqian, Xu, Jiahui, Li, Ying, Huang, Jumin, Jiang, Zebo, Wang, Yuwei, Liu, Liang, Leung, Elaine Lai Han, Yao, Xiaojun“…Many efforts have been taken in discovering small-molecular inhibitors against PRMT5, but very few were reported and most of them were SAM-competitive. EPZ015666 is a recently reported PRMT5 inhibitor with a new binding site, which is different from S-adenosylmethionine (SAM)-binding pocket. …”
Publicado 2018
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12894por Altmann, Mathias, Altare, Chiara, van der Spek, Nanette, Barbiche, Jean-Christophe, Dodos, Jovana, Bechir, Mahamat, Ait Aissa, Myriam, Kolsteren, Patrick“…The primary objective measures were the relapse rates to SAM at 2 and 6 months post-recovery. The secondary objectives included the recovery rate from SAM, the time-to-recovery, the weight gain, and the diarrhea longitudinal prevalence in OTP. …”
Publicado 2018
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12895por Arafat, Yasir, Islam, M Munirul, Connell, Nicki, Mothabbir, Golam, McGrath, Marie, Berkley, James A, Ahmed, Tahmeed, Kerac, Marko“…BACKGROUND: World Health Organization guidelines advise community-based care (CBC) for “uncomplicated” severe acute malnutrition (SAM) infants <6 months old (u6m), whereas current national protocols refer to inpatient care. …”
Publicado 2018
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12896por Cozier, Gyles E., Schwager, Sylva L., Sharma, Rajni K., Chibale, Kelly, Sturrock, Edward D., Acharya, K. Ravi“…In addition, the structures clearly show a significantly greater number of hydrophilic and hydrophobic interactions with sampatrilat compared to samAsp in both cACE and nACE consistent with the difference in affinities. …”
Publicado 2018
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12897por Byer, Amanda S., Yang, Hao, McDaniel, Elizabeth C., Kathiresan, Venkatesan, Impano, Stella, Pagnier, Adrien, Watts, Hope, Denler, Carly, Vagstad, Anna L., Piel, Jörn, Duschene, Kaitlin S., Shepard, Eric M., Shields, Thomas P., Scott, Lincoln G., Lilla, Edward A., Yokoyama, Kenichi, Broderick, William E., Hoffman, Brian M., Broderick, Joan B.“…[Image: see text] Radical S-adenosyl-l-methionine (SAM) enzymes comprise a vast superfamily catalyzing diverse reactions essential to all life through homolytic SAM cleavage to liberate the highly reactive 5′-deoxyadenosyl radical (5′-dAdo·). …”
Publicado 2018
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12898por Oldenburg, Catherine E, Guerin, Philippe J, Berthé, Fatou, Grais, Rebecca F, Isanaka, Sheila“…Here, we report bidirectional associations between malaria and nutritional status among children with uncomplicated severe acute malnutrition (SAM). METHODS: This study is a secondary analysis of a randomized, controlled trial for the treatment of uncomplicated SAM in Niger. …”
Publicado 2018
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12899por Chama, Mubanga, Amadi, Beatrice C., Chandwe, Kanta, Zyambo, Kanekwa, Besa, Ellen, Shaikh, Nurmohammad, Ndao, I. Malick, Tarr, Philip I., Storer, Chad, Head, Richard, Kelly, Paul“…BACKGROUND: Children with severe acute malnutrition (SAM), with or without diarrhoea, often have enteropathy, but there are few molecular data to guide development of new therapies. …”
Publicado 2019
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12900por Schwinger, Catherine, Golden, Michael H., Grellety, Emmanuel, Roberfroid, Dominique, Guesdon, Benjamin“…OBJECTIVES: This study aims to describe the mortality risk of children in the community who had severe acute malnutrition (SAM) defined by either a mid-upper arm circumference (MUAC) <115mm, a low weight-for-height Z-score (WHZ) <-3 or both criteria. …”
Publicado 2019
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