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12941“…This study established a microfluidic chip for the capture of A549 human lung circulating tumor cells via the aptamer-conjugated self-assembled monolayer (SAM) of gold nanoparticles (AuNPs) in the channel. …”
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12942“…The shoot apical meristem (SAM) plays a key role in forming all of the aerial structures of plants, including floral meristems (FMs). …”
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12943“…Carbohydrate and fats are converted into ATP, acetyl-CoA, SAM, and NADH. These high-energy substrates are, in turn, capable of driving the epigenetic profile. …”
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12944por Jia, Kaimin, Huang, Gaochao, Wu, Wei, Shrestha, Ruben, Wu, Bingbing, Xiong, Yulan, Li, Ping“…Together with motif sequence and signal peptide analyses, activity-based substrate profiling of NTMT1 utilizing (E)-hex-2-en-5-ynyl-S-adenosyl-l-methionine (Hey-SAM) revealed 72 potential targets, which include several previously confirmed ones and many unknowns. …”
Publicado 2019
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12945por Demmler, Richard, Fricke, Janis, Dörner, Sebastian, Gressler, Markus, Hoffmeister, Dirk“…Both enzymes are directly or indirectly involved in regenerating SAM. qRT‐PCR expression analysis revealed an induced expression of the genes in the fungal primordia and carpophores. …”
Publicado 2020
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12946“…The impairment of S-adenosylmethionine (SAM) synthesis from methionine (Met) in the fat body hampers the maintenance of KynA levels in hemolymph at the early stage of disc repair, suggesting a connection between Met-SAM and Trp-Kyn metabolisms. …”
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12947por Lenherr, Nina, Christodoulou, John, Duley, John, Dobritzsch, Doreen, Fairbanks, Lynette, Datta, Alexandre N., Filges, Isabel, Gürtler, Nicolas, Roelofsen, Jeroen, van Kuilenburg, André B.P., Kemper, Claudia, West, Erin E., Szinnai, Gabor, Huemer, Martina“…Treatment of a 3-year old boy with S-adenosylmethionine (SAM) replenished erythrocyte purine nucleotides of adenosine and guanosine, while SAM and nicotinamide riboside co-therapy further improved his clinical phenotype as well as T-cell survival and function.…”
Publicado 2021
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12948“…The knowledge of the molecular mechanisms that drive the recognition of small molecules on SAM-covered nanoparticles will critically expand our ability to manipulate and control such supramolecular systems.…”
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12949“…LVOT myectomy and edge-to-edge mitral valve repair may be considered as a safe and acceptable approach with good clinical outcomes in pediatric patients with LVOTS accompanied by MR with SAM.…”
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12950por van Haren, Matthijs J., Zhang, Yurui, Thijssen, Vito, Buijs, Ned, Gao, Yongzhi, Mateuszuk, Lukasz, Fedak, Filip A., Kij, Agnieszka, Campagna, Roberto, Sartini, Davide, Emanuelli, Monica, Chlopicki, Stefan, Jongkees, Seino A. K., Martin, Nathaniel I.“…Interestingly, substrate competition experiments reveal that these cyclic peptide inhibitors are noncompetitive with either SAM or NA indicating they may be the first allosteric inhibitors reported for NNMT.…”
Publicado 2021
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12951“…To the best of our knowledge, this is the first case of OMS seen in a patient with severe acute malnutrition (SAM). Parents brought a three-year-old female child with complaints of being unable to sit, stand, and hold her neck for the past 18 months. …”
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12952por Gehrig, Jeanette L., Venkatesh, Siddarth, Chang, Hao-Wei, Hibberd, Matthew C., Kung, Vanderlene L., Cheng, Jiye, Chen, Robert Y., Subramanian, Sathish, Cowardin, Carrie A., Meier, Martin F., O’Donnell, David, Talcott, Michael, Spears, Larry D., Semenkovich, Clay F., Henrissat, Bernard, Giannone, Richard J., Hettich, Robert L., Ilkayeva, Olga, Muehlbauer, Michael, Newgard, Christopher B., Sawyer, Christopher, Head, Richard D., Rodionov, Dmitry A., Arzamasov, Aleksandr A., Leyn, Semen A., Osterman, Andrei L., Hossain, Md Iqbal, Islam, Munirul, Choudhury, Nuzhat, Sarker, Shafiqul Alam, Huq, Sayeeda, Mahmud, Imteaz, Mostafa, Ishita, Mahfuz, Mustafa, Barratt, Michael J., Ahmed, Tahmeed, Gordon, Jeffrey I.“…RESULTS: Metabolomic and proteomic analyses of serially collected plasma samples were combined with metagenomic analyses of serially collected fecal samples from Bangladeshi children with severe acute malnutrition (SAM) treated with standard therapy. The results provided a readout of their biological features as they transitioned from SAM to a state of persistent moderate acute malnutrition (MAM) with accompanying persistent microbiota immaturity. …”
Publicado 2019
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12953por Silver, HoraceTabla de Contenidos: “…Song for my father -- The natives are restless tonight -- Calcutta cutie -- Que pasa -- The kicker / Joe Henderson -- Lonely woman -- Sanctimonious Sam / Musa Kaleem -- Que pasa (trio version) -- Sighin' and cryin' -- Silver treads among my soul.…”
Publicado 1989
CD Audiom -
12954por Sturgeon, Jonathan P., Mufukari, Wadzanai, Tome, Joice, Dumbura, Cherlynn, Majo, Florence D., Ngosa, Deophine, Chandwe, Kanta, Kapoma, Chanda, Mutasa, Kuda, Nathoo, Kusum J., Bourke, Claire D., Ntozini, Robert, Bwakura-Dangarembizi, Mutsa, Amadi, Beatrice, Kelly, Paul, Prendergast, Andrew J.“…A better understanding of the pathophysiology of SAM is needed to identify adjunctive interventions.…”
Publicado 2023
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12955“…BACKGROUND: Self-administered medication (SAM) is encouraged in many hospitals worldwide as it increases patients’ knowledge and understanding of their medication, but the effects on other outcomes, e.g. compliance or medication errors, were unclear. …”
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12956por Kozuki, Naoko, Seni, Mamoudou, Sirat, Amin, Abdullahi, Omar, Adalbert, Mena Fundi Eso, Biotteau, Marie, Goldsmith, Amelia, Dalglish, Sarah L.“…Current global outpatient treatment protocols for uncomplicated SAM and MAM, adapted by most countries for use at national level, call for SAM and MAM to be managed separately, however global-level stakeholders have recently begun evaluating simplified and/or combined protocols managing acute malnutrition. …”
Publicado 2020
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12957“…RESULTS: MSI-195 was found to be generally well tolerated with an adverse event profile similar to the SAM-e Complete™ comparator product. The relative bioavailability of MSI-195 was approximately 2.8-fold higher than SAM-e Complete based on area under the curve (AUC) ratios for the two products and the MSI-195 formulation exposure based on AUC was found to be approximately dose proportional. …”
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12958por Eyi, Seyum Ebissa, Debele, Gebiso Roba, Negash, Efrem, Bidira, Kebebe, Tarecha, Debela, Nigussie, Kabtamu, Hajure, Mohammedamin, Ahmed, Mohammedjud Hassen, Kefeni, Bilisumamulifna Tefera“…BACKGROUND: Despite currently available, scientifically proven treatments and national guideline, the SAM recovery rate is still considerably behind expectations, and it continues to have a devastating impact on under-five children. …”
Publicado 2022
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12959
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12960