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  1. 12981
    por Litke, Jacob L., Jaffrey, Samie R.
    Publicado 2019
    “…Additionally, an RNA-based fluorescent metabolite biosensor for S-adenosyl methionine (SAM) that is expressed at low levels when expressed as a linear RNA achieves levels sufficient for detection of intracellular SAM dynamics when expressed as a circular RNA. …”
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    Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts
  2. 12982
    “…Sulfur assimilation and the biosynthesis of methionine, cysteine and S-adenosylmethionine (SAM) are critical to life. As a cofactor, SAM is required for the activity of most methyltransferases (MTases) and as such has broad impact on diverse cellular processes. …”
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    Network dynamics of the yeast methyltransferome
  3. 12983
    “…We present the self-assembling manifold (SAM) algorithm, an iterative soft feature selection strategy to quantify gene relevance and improve dimensionality reduction. …”
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    Self-assembling manifolds in single-cell RNA sequencing data
  4. 12984
    “…Moreover, spectral angle mapper (SAM) was utilized as chemometrics to discriminate gastric cancer from normal. …”
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    Gastric cancer diagnosis using hyperspectral imaging with principal component analysis and spectral angle mapper
  5. 12985
    “…Our results showed that SAM encapsulating DOTAP polymeric nanoparticles, DOTAP liposomes and DDA liposomes induced the highest antigen expression in vitro and, from these, DOTAP polymeric nanoparticles were the most potent in triggering humoral and cellular immunity among candidates in vivo.…”
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    Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines
  6. 12986
    por Kowluru, Renu A.
    Publicado 2020
    “…Furthermore, homocysteine biosynthesis from methionine forms S-adenosyl methionine (SAM), and SAM is a co-substrate of DNA methylation. …”
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    Diabetic Retinopathy: Mitochondria Caught in a Muddle of Homocysteine
  7. 12987
    “…We report the first documented case of an HEV infection in a 36-month-old child already suffering from HIV and severe acute malnutrition (SAM). The HIV patient was hospitalized for SAM with persistent diarrhea and prolonged fever. …”
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    Fatal Outcome in a Hepatitis E Virus/Human Immunodeficiency Virus Co-Infected Malnourished Child in the Central African Republic
  8. 12988
    “…In this paper, tractive rolling contact under the effect of friction is modeled by Kalker’s theory using a semi-analytical method (SAM). A tire profile is performed thanks to a digitization by fringes or a photogrammetry technique. …”
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    Approach of Pavement Surface Layer Degradation Caused by Tire Contact Using Semi-Analytical Model
  9. 12989
    por Bekdash, Rola A
    Publicado 2021
    “…Micronutrients that act as methyl donors for SAM formation could affect global or gene methylation, altering gene expression and phenotype. …”
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    Early Life Nutrition and Mental Health: The Role of DNA Methylation
  10. 12990
    por Kennedy, Czara A, Toomey, Desmond P
    Publicado 2021
    “…Segmental arterial mediolysis (SAM) is a nonatherosclerotic, noninflammatory and nonimmune arteriopathy of unknown aetiology. …”
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    Segmental arterial mediolysis: a rare cause of an acute abdomen
  11. 12991
    “…Secondly, a fingerprint study against SAM preferred compounds 44, 48, 85, 102, 105, 182, 220, 221, 282, 284, 285, 301, and 302. …”
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    In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10
  12. 12992
    “…In this study, we investigate the role of the atomic force microscopy (AFM) feedback (contact mode and tapping mode) on molecular perturbation in TERS analysis of soft samples using a self-assembled monolayer (SAM) of 2-chloro-4-nitrobenzene-1-thiol (Cl-NBT) as a test sample. …”
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    Molecular Perturbation Effects in AFM-Based Tip-Enhanced Raman Spectroscopy: Contact versus Tapping Mode
  13. 12993
    “…Herein, we designed innovative and smart phosphonium self-assembled monolayer (SAM) interfaces that can be electrically activated on demand for controlling bacterial contaminations on solid surfaces. …”
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    Nanoarchitectonics of Electrically Activable Phosphonium Self-Assembled Monolayers to Efficiently Kill and Tackle Bacterial Infections on Demand
  14. 12994
    por G, Gokul, Singh, Jogender
    Publicado 2022
    “…Using a forward genetic screen, we discover that loss-of-function of R08E5.3, an S-adenosylmethionine (SAM)-dependent methyltransferase, confers DTT resistance. …”
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    Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle
  15. 12995
    “…One such promising chemical strategy is the formation of a self-assembled monolayer (SAM), due to its small layer thickness, strong covalent bonds, typically facile synthesis, and versatility. …”
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    Functionalized Self-Assembled Monolayers: Versatile Strategies to Combat Bacterial Biofilm Formation
  16. 12996
    “…The key idea is to control the Fermi level of the graphene using the consecutive treatment of gold nanoparticles (AuNPs) and thiol-SAM (self-assembled monolayer) molecules, inducing positive and negative doping effects, respectively, by flipping the electric dipoles between AuNPs and SAMs. …”
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    Gold nanoparticle-mediated non-covalent functionalization of graphene for field-effect transistors
  17. 12997
    “…The photocurrent density and power conversion efficiency of organic solar cells employing the fullerene-SAM-treated interlayer were ~10% higher than those of the device employing the nontreated interlayer. …”
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    Modification of Electrode Interface with Fullerene-Based Self-Assembled Monolayer for High-Performance Organic Optoelectronic Devices
  18. 12998
    “…However, most inhibitors reported recently act in a SAM-competitive mode and lack structural diversity. …”
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    Structure-Based Discovery and Biological Assays of a Novel PRMT5 Inhibitor for Non-Small Cell Lung Cancer
  19. 12999
    “…A metabolome analysis revealed that L63 plants had a more active SAM cycle and a greater capacity for terpenoid synthesis and phenylalanine metabolism than L42. …”
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    Integration of Transcriptome and Metabolome Analyses Reveals the Mechanistic Basis for Cadmium Accumulation in Maize
  20. 13000
    “…Cardiac amyloidosis can occasionally demonstrate an atypical pattern of infiltration, causing asymmetric septal thickening and a left ventricular outflow tract (LVOT) gradient with systolic anterior motion (SAM) of the mitral valve resembling obstructive hypertrophic cardiomyopathy. …”
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    Alcohol septal ablation for left ventricular outflow tract obstruction in cardiac amyloidosis: New indication for an established therapy
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