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  1. 13321
    “…PCE reduced placental components of 1CM, particularly those relating to folate metabolism, resulting in a 3–7.5-fold reduction in the ratio of s-adenosylmethionine:s-adenosylhomocysteine (SAM:SAH) (p < 0.0001). Choline supplementation increased placental 1CM components and the SAM:SAH ratio (3.5–14.5-fold, p < 0.0001). …”
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    Prenatal Choline Supplementation Alters One Carbon Metabolites in a Rat Model of Periconceptional Alcohol Exposure
  2. 13322
    “…We identified gene specific Synergistic Activation Mediators (SAM) from the CRISPR/Cas9 system for targeted overexpression of coagulation factors II, VII, IX, X, and fibrinogen. …”
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    Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production
  3. 13323
    “…The expression of stress-related gene candidate sam2 increased in the brain of older individuals exposed to stress. …”
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    Age-Dependent Effects of Chronic Stress on Zebrafish Behavior and Regeneration
  4. 13324
    “…Lastly, we apply a technique called sharpness aware minimization (SAM) that helps improve the generalizability of networks. …”
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    Deep Learning-Based Total Kidney Volume Segmentation in Autosomal Dominant Polycystic Kidney Disease Using Attention, Cosine Loss, and Sharpness Aware Minimization
  5. 13325
    “…More specifically, we focus on an iron-containing MOF, MIL-88B(Fe), on a COOH-terminated self-assembled monolayer (SAM) modified Au surface for encapsulating ibuprofen as a model drug. …”
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    Iron-containing metal-organic framework thin film as a drug delivery system
  6. 13326
    “…The interaction with UFD‐2 enables CHN‐1 to efficiently ubiquitylate and regulate S‐adenosylhomocysteinase (AHCY‐1), a key enzyme in the S‐adenosylmethionine (SAM) regeneration cycle, which is essential for SAM‐dependent methylation. …”
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    A heterotypic assembly mechanism regulates CHIP E3 ligase activity
  7. 13327
    “…Positive SAM was correlated to FO for both species, and wind and season were important for redbait, while SOI and SST were important for pilchard. …”
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    Environmental correlates of temporal variation in the prey species of Australian fur seals inferred from scat analysis
  8. 13328
    “…We found that NNMT overexpression reduced NAD(+) and SAM levels, and activated the STAT3 signaling pathway. …”
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    Nicotinamide N-Methyltransferase Remodeled Cell Metabolism and Aggravated Proinflammatory Responses by Activating STAT3/IL1β/PGE(2) Pathway
  9. 13329
    “…In DN (dysplastic nodule) and HCC of F344 rats and human HCCP, DUSP1 downregulation and ERK1/2 overexpression sustain SKP2-CKS1 activity through FOXM1, the expression of which is associated with a susceptible phenotype. SAM-methyl-transferase reactions and SAM/SAH ratio are regulated by GNMT. …”
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    Genetic Predisposition to Hepatocellular Carcinoma
  10. 13330
    “…In Bihar state, of children <5 y old, 27.1% are wasted and 8.3% have severe acute malnutrition (SAM). In 2009, Médecins Sans Frontières (MSF) initiated a community-based management of acute malnutrition (CMAM) program for children aged 6–59 mo with SAM. …”
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    Community-based management of severe acute malnutrition in India: new evidence from Bihar(1)(2)(3)
  11. 13331
    “…RESULTS: Patients will be randomised 1:1 to receive either OLZ or ALKS 3831 treatment for 12 weeks. ALKS 3831 (OLZ + SAM) and matched OLZ + placebo (OLZ + PBO) will be provided as bilayer tablets to be taken by mouth once daily and doses will include ALKS 3831 (OLZ/SAM) 5/10 mg, 10/10 mg, 15/10 mg, 20/10 mg, or (OLZ/PBO) 5 mg, 10 mg, 15 mg, or 20 mg. …”
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    S226. A STUDY COMPARING WEIGHT GAIN FROM ALKS 3831 TO OLANZAPINE IN EARLY-ILLNESS YOUNG ADULTS WITH SCHIZOPHRENIFORM, SCHIZOPHRENIA, OR BIPOLAR I DISORDER
  12. 13332
    “…BACKGROUND: Severe acute malnutrition (SAM) threatens the lives of millions of children worldwide particularly in low and middle-income countries (LMICs). …”
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    Mid-upper-arm circumference based case-detection, admission, and discharging of under five children in a large-scale community-based management of acute malnutrition program in Nigeria
  13. 13333
    “…To overcome this problem, in this paper, an attempt is made to propose a hybrid robust SAM-FC approach by combining rank of FC values and rank of p-values computed by SAM statistic using minimum β-divergence method, which is designed for paired samples. …”
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    A Robust Approach for Identification of Cancer Biomarkers and Candidate Drugs
  14. 13334
    “…BACKGROUND: Alisol A-24-acetate (AA-24-a) is one of the main active triterpenes isolated from the well-known medicinal plant Alisma orientale (Sam.) Juz., which possesses multiple biological activities, including a hypoglycemic effect. …”
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    Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes
  15. 13335
    “…BACKGROUND: Self-administration of medication (SAM) during hospitalization is a complex intervention where patients are involved in their course of treatment. …”
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    Self-administration of medication during hospitalization—a randomized pilot study
  16. 13336
    “…Stressful stimuli evoke a complex response mediated by two systems: the Sympathetic-Adreno-Medullar (SAM) axis and the Hypothalamus-Pituitary-Adrenal (HPA) axis. …”
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    Effects of L-3,4-dihydroxyphenylalanine (L-Dopa) Treatment in the Neuroendocrine Response to Stress
  17. 13337
    “…RESULTS: Frequencies and SAM percent ratings of eligible tools were reported. …”
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    Multimedia Knowledge Translation Tools for Parents About Childhood Heart Failure: Environmental Scan
  18. 13338
    “…The Society for Acute Medicine (SAM) recommend a ‘nurse-to-bed‘ratio of greater than 1:6. …”
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    Nurse staffing levels within acute care: results of a national day of care survey
  19. 13339
    “…Co-supplementation with vitamin D, folic acid, and vitamin B(12) significantly reverses this effect by affecting the expression of CYP27A1, which in turn regulates the metabolism of 27-OHC, 25(OH)D, and SAM.…”
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    Vitamin D, Folic Acid and Vitamin B(12) Can Reverse Vitamin D Deficiency-Induced Learning and Memory Impairment by Altering 27-Hydroxycholesterol and S-Adenosylmethionine
  20. 13340
    “…However, given the downregulation of SAM, a regulator of genomic imprinting, the potential risk of imprinting disturbances should not be neglected. …”
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    The effect of growth hormone on the metabolome of follicular fluid in patients with diminished ovarian reserve
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