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13521por Terova, Genciana, Ceccotti, Chiara, Ascione, Chiara, Gasco, Laura, Rimoldi, Simona“…In particular, Met availability from the insect-based diets directly modulated the transcript levels of two out of three target genes (CBS, SAHH) to maintain an optimal level of one-carbon metabolic substrates, i.e., the SAM:SAH ratio in the hepatic tissue.…”
Publicado 2020
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13522por Viswanathan, Thiruselvam, Arya, Shailee, Chan, Siu-Hong, Qi, Shan, Dai, Nan, Misra, Anurag, Park, Jun-Gyu, Oladunni, Fatai, Kovalskyy, Dmytro, Hromas, Robert A., Martinez-Sobrido, Luis, Gupta, Yogesh K.“…We also discover a distant (25 Å) ligand-binding site unique to SARS-CoV-2, which can alternatively be targeted, in addition to RNA cap and SAM pockets, for antiviral development.…”
Publicado 2020
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13523por Fling, Russell R., Doskey, Claire M., Fader, Kelly A., Nault, Rance, Zacharewski, Tim R.“…However, the dose-dependent effects on SAM-dependent metabolism of polyamines and creatine could not be directly attributed to alterations in SAM levels. …”
Publicado 2020
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13524por Abreu, José, Phillips, Richard A., Ceia, Filipe R., Ireland, Louise, Paiva, Vítor H., Xavier, José C.“…By comparison, mean δ(15)N values were similar across decades for all five species, suggesting minimal changes in trophic levels. Both SAM and SOI have increased in strength and frequency over the study period but, of the five species, only in Taonius sp. …”
Publicado 2020
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13525“…The [(19)F, (13)C]‐labeling of the SAM VI aptamer domain and the pre‐miRNA 21 further opens the possibility to use the biorthogonal stable isotope reporter nuclei in in vivo NMR to observe ligand binding and microRNA processing in a biological relevant setting.…”
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13526por Durhuus, Jon Ambæk, Hansson, Svenja, Morville, Thomas, Kuhlman, Anja Birk, Dohlmann, Tine Lovsø, Larsen, Steen, Helge, Jørn Wulff, Angleys, Maria, Muniesa-Vargas, Alba, Bundgaard, Jens R., Hickson, Ian David, Dela, Flemming, Desler, Claus, Rasmussen, Lene Juel“…Although a proposed mechanism responsible for Statin-Associated Myopathy (SAM) suggests a correlation with impairment of mitochondrial function, the relationship is still poorly understood. …”
Publicado 2020
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13527“…It eliminates obstruction in the LVOT and SAM, resulting in LV remodeling with an increase in LV end-diastolic volume and diameter at early follow-up.…”
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13528“…These beams, being superposition of orthogonal orbital angular momentum (OAM) states in orthogonal spin angular momentum (SAM) states can offer great multiplexing capabilities in communication. …”
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13529“…The decline in the R(ct) of the immunosensor started at 10 min of EPPS incubation and continued to decrease gradually from 20 min, indicating that the accumulation of aβ(agg) on the surface of the anti-aβ/SAM/ICE sensor has been extricated. Here, the kinetic disaggregation rate k value of aβ(agg) was found to be 0.038. …”
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13530“…Transoesophageal echocardiography revealed LVOT obstruction due to SAM of the mitral valve associated with severe mitral regurgitation (MR), which was not observed preoperatively. …”
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13531por Kubo, Shun, Yamamoto, Haruka, Kajimura, Naoko, Omori, Yoshihiro, Maeda, Yamato, Chaya, Taro, Furukawa, Takahisa“…In the current study, we analyzed a functional role of Samd11, another photoreceptor-enriched SAM-domain protein, in photoreceptor differentiation and maturation. …”
Publicado 2021
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13532“…The improvement in the SAM was visualized on echocardiography and was haemodynamically corroborated by the four-dimensional (4D)-flow cardiac magnetic resonance (CMR). …”
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13533por Guo, Yinghui, Zhang, Shicong, Pu, Mingbo, He, Qiong, Jin, Jinjin, Xu, Mingfeng, Zhang, Yaxin, Gao, Ping, Luo, Xiangang“…With inherent orthogonality, both the spin angular momentum (SAM) and orbital angular momentum (OAM) of photons have been utilized to expand the dimensions of quantum information, optical communications, and information processing, wherein simultaneous detection of SAMs and OAMs with a single element and a single-shot measurement is highly anticipated. …”
Publicado 2021
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13534por Mora-Hernández, Y., Vera Murguía, E., Stinenbosch, J., Hernández Jauregui, P., van Dijl, Jan Maarten, Buist, G.“…Lastly, many isolates carried the same small plasmid, designated pSAM1. The high prevalence of pSAM1 amongst the antimicrobial-susceptible isolates suggests an association with bovine colonization or mastitis rather than antimicrobial resistance.…”
Publicado 2021
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13535“…The NTER or part of it plays critical roles in selective recognition of substrate RNA by Erms and this presumed target site might assume distinct local structure by induced conformational change with binding to substrate RNA and SAM, and contribute to the specific recognition of substrate RNA.…”
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13536por Liu, Yuelin, Luo, Weifeng, Linghu, Qianyan, Abe, Fumitaka, Hisano, Hiroshi, Sato, Kazuhiro, Kamiya, Yoko, Kawaura, Kanako, Onishi, Kazumitsu, Endo, Masaki, Toki, Seiichi, Hamada, Haruyasu, Nagira, Yozo, Taoka, Naoaki, Imai, Ryozo“…Taken together, this report demonstrates that the in planta genome editing method through SAM bombardment can be applicable to elite wheat varieties that are otherwise reluctant to callus culture.…”
Publicado 2021
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13537por Liu, Mingze, Huo, Pengcheng, Zhu, Wenqi, Zhang, Cheng, Zhang, Si, Song, Maowen, Zhang, Song, Zhou, Qianwei, Chen, Lu, Lezec, Henri J., Agrawal, Amit, Lu, Yanqing, Xu, Ting“…The term Poincaré beam, which describes the space-variant polarization of a light beam carrying spin angular momentum (SAM) and orbital angular momentum (OAM), plays an important role in various optical applications. …”
Publicado 2021
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13538por Ünzelmann, M., Bentmann, H., Figgemeier, T., Eck, P., Neu, J. N., Geldiyev, B., Diekmann, F., Rohlf, S., Buck, J., Hoesch, M., Kalläne, M., Rossnagel, K., Thomale, R., Siegrist, T., Sangiovanni, G., Sante, D. Di, Reinert, F.“…The experiments reveal large spin- and orbital-angular-momentum (SAM and OAM) polarizations of the Weyl-fermion states, resulting from the broken crystalline inversion symmetry in TaAs. …”
Publicado 2021
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13539“…For RNA methylation, cells use methyltransferases and small organic substances as methyl-group donors, such as S-adenosylmethionine (SAM). SAM and other nucleotide-derived cofactors are viewed as evolutionary leftovers from an RNA world, in which riboswitches have regulated, and ribozymes have catalyzed essential metabolic reactions. …”
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13540por Fischer, Natalie, Darmstadt, Gary L, Shahunja, KM, Crowther, Jonathan M, Kendall, Lindsay, Gibson, Rachel A, Ahmed, Tahmeed, Relman, David A“…RESULTS: The skin microbiota of Bangladeshi children with SAM was highly diverse and displayed significant variation in structure as a function of physical distance between sites. …”
Publicado 2021
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