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14501por Fislage, Marcus, Roovers, Martine, Tuszynska, Irina, Bujnicki, Janusz M., Droogmans, Louis, Versées, Wim“…Structures of (Pf)Trm14 were solved in complex with the methyl donor S-adenosyl-l-methionine (SAM or AdoMet), as well as the reaction product S-adenosyl-homocysteine (SAH or AdoHcy) and the inhibitor sinefungin. …”
Publicado 2012
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14502por Lohse, Marc, Bolger, Anthony M., Nagel, Axel, Fernie, Alisdair R., Lunn, John E., Stitt, Mark, Usadel, Björn“…RobiNA accepts raw FastQ files, SAM/BAM alignment files and counts tables as input. …”
Publicado 2012
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14503“…Fifty rice farmers from Khlong Seven Community (study group) and 51 rice farmers from Bueng Ka Sam community (control group) were randomly recruited with support from community leaders. …”
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14504“…Although each of the four cysteines is essential for folding of the protein and binding to mitofilin and Sam50, they are not involved in import. Together our results indicate that both the myristoylation and the CHCH domain are essential for the import and mitochondrial localization of ChChd3. …”
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14505por Monticone, Massimiliano, Daga, Antonio, Candiani, Simona, Romeo, Francesco, Mirisola, Valentina, Viaggi, Silvia, Melloni, Ilaria, Pedemonte, Simona, Zona, Gianluigi, Giaretti, Walter, Pfeffer, Ulrich“…Subsequently, individual genes with different expression levels between the two groups were identified using Significance Analysis of Microarrays (SAM). Real time RT-PCR, immunofluorescence and immunoblot analyses, were performed for a selected subgroup of regulated gene products to confirm the results obtained by the expression analysis. …”
Publicado 2012
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14506“…This article describes miRDeep*, our integrated miRNA identification tool, which is modeled off miRDeep, but the precision of detecting novel miRNAs is improved by introducing new strategies to identify precursor miRNAs. miRDeep* has a user-friendly graphic interface and accepts raw data in FastQ and Sequence Alignment Map (SAM) or the binary equivalent (BAM) format. Known and novel miRNA expression levels, as measured by the number of reads, are displayed in an interface, which shows each RNAseq read relative to the pre-miRNA hairpin. …”
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14507“…Grape supports raw sequencing reads produced by a variety of technologies, either in FASTA or FASTQ format, or as prealigned reads in SAM/BAM format. A minimal Grape configuration consists of the file location of the raw sequencing reads, the genome of the species and the corresponding gene and transcript annotation. …”
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14508“…The blue mounting plates replace the standard yellow SAM mounting elements. The red spacers provide for a defined leeway of 8 mm for three-dimensional movements. …”
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14509por Sawano, Erika, Negishi, Takayuki, Aoki, Tomoyuki, Murakami, Masami, Tashiro, Tomoko“…The senescence-accelerated mouse (SAM) strains were established through selective inbreeding of the AKR/J strain based on phenotypic variations of aging and consist of senescence-prone (SAMP) and senescence-resistant (SAMR) strains. …”
Publicado 2013
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14510por Guo, Aijiang, Cai, Jianping, Gong, Wei, Yan, Hongbin, Luo, Xuenong, Tian, Guangfu, Zhang, Shaohua, Zhang, Haili, Zhu, Guan, Cai, Xuepeng“…By Significance Analysis of Microarrays (SAM), we have identified 7,099 probe sets with q-values at <0.05, in which 4,033 and 3,066 genes were found to be up- or down-regulated in response to parasite infection. …”
Publicado 2013
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14511por Dominguez-Valentin, Mev, Therkildsen, Christina, Veerla, Srinivas, Jönsson, Mats, Bernstein, Inge, Borg, Åke, Nilbert, Mef“…RESULTS: Colorectal cancers linked to Lynch syndrome and FCCTX showed distinct gene expression profiles, which by significance analysis of microarrays (SAM) differed by 2188 genes. Functional pathways involved were related to G-protein coupled receptor signaling, oxidative phosphorylation, and cell cycle function and mitosis. qRT-PCR verified altered expression of the selected genes NDUFA9, AXIN2, MYC, DNA2 and H2AFZ. …”
Publicado 2013
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14512“…Our application accepts three standard ChIP-seq data formats: BED, BAM, and SAM. RESULTS: Sensitivity and specificity of seven widely used peak finders were examined. …”
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14513“…Ratings of subjectively experienced affect (arousal and valence) were assessed using Self-Assessment Manikins (SAM) (Bradley and Lang, 1994) in a sample of 84 participants. …”
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14514“…Participants rated the emotional valence of the stimuli adopting self- and others-perspective by using a 5-point version of the Self-Assessment Manikin (SAM). Familiarity was assessed based on subjective rating, objective labelling of the respective stimuli and interaction time with the respective species. …”
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14515por Chu, Uyen B., Vorperian, Sevahn K., Satyshur, Kenneth, Eickstaedt, Kelsey, Cozzi, Nicholas V., Mavlyutov, Timur, Hajipour, Abdol R., Ruoho, Arnold E.“…DMT is produced via the action of INMT on the endogenous substrates tryptamine and S-adenosyl-l-methionine (SAM). The biological, biochemical, and selective small molecule regulation of INMT enzyme activity remain largely unknown. …”
Publicado 2014
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14516por Bernkopf, Marie, Webersinke, Gerald, Tongsook, Chanakan, Koyani, Chintan N., Rafiq, Muhammad A., Ayaz, Muhammad, Müller, Doris, Enzinger, Christian, Aslam, Muhammad, Naeem, Farooq, Schmidt, Kurt, Gruber, Karl, Speicher, Michael R., Malle, Ernst, Macheroux, Peter, Ayub, Muhammad, Vincent, John B., Windpassinger, Christian, Duba, Hans-Christoph“…Both changes lead to truncation of the putative METTL23 protein, which disrupts the predicted catalytic domain and alters the cellular localization. 3D-modelling of the protein indicates that METTL23 is strongly predicted to function as an S-adenosyl-methionine (SAM)-dependent methyltransferase. Expression analysis of METTL23 indicated a strong association with heat shock proteins, which suggests that these may act as a putative substrate for methylation by METTL23. …”
Publicado 2014
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14517por Chou, He-Yen, Lin, Yu-Hung, Shiu, Guan-Lin, Tang, Hsiang-Yu, Cheng, Mei-Ling, Shiao, Ming-Shi, Pai, Li-Mei“…In addition, we found that three compounds namely, methionine, SAM and Methionine sulfoxide, respectively, may be required for normal fecundity. …”
Publicado 2014
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14518por DeOcesano-Pereira, Carlos, Amaral, Murilo S., Parreira, Kleber S., Ayupe, Ana C., Jacysyn, Jacqueline F., Amarante-Mendes, Gustavo P., Reis, Eduardo M., Verjovski-Almeida, Sergio“…INXS is an unspliced 1903 nt-long RNA, is transcribed by RNA polymerase II, 5′-capped, nuclear enriched and binds Sam68 splicing-modulator. Three apoptosis-inducing agents increased INXS lncRNA endogenous expression in the 786-O kidney tumor cell line, increased BCL-XS/BCL-XL mRNA ratio and activated caspases 3, 7 and 9. …”
Publicado 2014
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14519por Ioakeimidis, Fotis, Ott, Christine, Kozjak-Pavlovic, Vera, Violitzi, Foteini, Rinotas, Vagelis, Makrinou, Eleni, Eliopoulos, Elias, Fasseas, Costas, Kollias, George, Douni, Eleni“…Moreover, we showed that DNAJC11 is assembled in a high molecular weight complex, similarly to mitofilin and that downregulation of mitofilin or SAM50 affected the levels of DNAJC11 in HeLa cells. …”
Publicado 2014
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14520por Fantappiè, Laura, de Santis, Micaela, Chiarot, Emiliano, Carboni, Filippo, Bensi, Giuliano, Jousson, Olivier, Margarit, Immaculada, Grandi, Guido“…Group A Streptococcus (GAS) Slo, SpyCEP, Spy0269 and Group B Streptococcus (GBS) SAM_1372 were fused to the OmpA leader sequence for secretion and expressed in Escherichia coli. …”
Publicado 2014
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