“…Thus, TPM values were calculated by processing the Sequence Alignment Map (SAM) file in R using package Rsubread and subsequently in python. …”
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“…The Motif Finder server identified the protein family domain FLO_LFY and LFY_SAM, whose function is floral meristem development. …”
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“…By Tnk1 expression in mammalian cells, we found that the N-terminal SAM domain is important for self-association and kinase activity. …”
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“…We further explored whether the FT-sgRNA strategy could transport sgRNA to cotton apical meristem (SAM) over long distances to avoid using tissue culture to obtain stable genetic mutants. …”
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“…This is complemented by a comparative analysis of three DSTs that represent the state of the art in their respective typologies: RobecoSAM’s Country Sustainability Rankings, IFC Performance Standards, and ETH’s Impact ÆSSURANCE Sovereign Ratings. …”
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“…Laboratory and clinical studies have revealed the importance of gut microbiota in children with severe pediatric pathological conditions such as severe acute malnutrition (SAM); however, under relatively milder conditions such as, failure to thrive (FTT), the role of the gut microbiota remains poorly characterized. …”
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“…AIMS: This study aimed to evaluate the effects of the depletion of SAM and SH3 domain‐containing protein 1 (SASH1) on functional recovery after spinal cord injury (SCI) and to investigate the possible mechanism of SASH1 knockdown in astrocytes facilitating axonal growth. …”
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“…Hence, this work based on the Bio Social Accounting Matrix (BioSAM) for Spain for the year 2010 with a high disaggregation of bio products to perform a structural analysis based on two different and complementary methods: the traditional and the Hypothetical Extraction approach. …”
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“…We have determined the structure of NSP14 in complex with cap analogue (7Me)GpppG, and observe conformational changes within a SAM/SAH interacting loop that plays a key role in viral mRNA capping offering new insights into MTase activity. …”
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“…Using the standard addition method (SAM) based on the Gran plot, CAP was satisfactorily determined throughout the concentration range of 0.83–13.04 mg/mL (SD = 0.20, R = 0.9986 (n = 5)), with a detection limit of 0.64 mg/mL (SD = 0.20, R = 0.9986 (n = 5)). …”
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“…Here, we thoroughly benchmark six recently published methods: CellDMC, CARseq, TOAST, LRCDE, CeDAR and TCA, together with two classical methods, csSAM and DESeq2, for a comprehensive comparison. …”
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“…Activation of the interleukin (IL)-13 receptor leads to STAT6 activation and subsequent induction of SAM pointed domain containing ETS transcription factor (SPDEF), chloride channel accessory 1 (CLCA1), and anoctamin-1 (ANO1), all of which are associated with the induction of MUC5AC. …”
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“…The AutoDock-based LBEs for nsp16 of SARS-CoV-2 ranged from −11.42 to −16.11 kcal/mol with predicted inhibition constants (pKi) from 0.002 to 4.51 nM, the natural substrate S-adenosyl methionine (SAM) was used as control. In silico results were verified by microscale thermophoresis as in vitro assay. …”
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“…SAM domain-containing protein 1 (SAMD1) has been implicated in atherosclerosis, as well as in chromatin and transcriptional regulation, suggesting a versatile and complex biological function. …”
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“…The five known SMYD enzymes catalyze the transfer of donor methyl groups from S-adenosylmethionine (SAM) to specific lysines on histones and non-histone substrates. …”
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“…DISCUSSION: The multivariate techniques employed in the present study highlight the importance of applying our source reconstruction techniques which leverage the high spatial localization abilities of MEG for estimating neural source activity using beamforming methods such as SAM (synthetic aperture morphometry) to reconstruct the source of brain activity, together with functional connectivity assessments, assayed with imaginary coherence metrics, to delineate how neurophysiological dysconnectivity in specific oscillatory frequencies between distinct regions underlie the cognitive and psychotic symptoms in SZ. …”
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“…Multiple proteins and metabolites, such as pre-melanosome protein (PMEL) and S-adenosylmethionine (SAM), demonstrated both diagnostic and prognostic effects. …”
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“…WHALE already provides many plugins useful for a LCG site and some more for a Tier-2 of the CMS experiment, expecially in the field of job management, dataset transfer and analysis of performance results and availability tests (eg. Nagios tests, SAM tests). Thanks to its architecture and the provided plugins WHALE makes easy to perform tasks that, even if logically simple, are technically complex or tedious, like eg. closing all the worker nodes with a job-failure rate greater than a given threshold. …”
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