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14841por Simile, Maria M., Peitta, Graziella, Tomasi, Maria L., Brozzetti, Stefania, Feo, Claudio F., Porcu, Alberto, Cigliano, Antonio, Calvisi, Diego F., Feo, Francesco, Pascale, Rosa M.“…These molecular events were paralleled by an increase in SAM content and were associated with growth restraint and apoptosis, inhibition of cell migration and invasiveness, and suppression of the expression of CD133 and LIN28B stemness markers. …”
Publicado 2019
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14842por Orenbuch, Ayelet, Fortis, Keren, Taesuwan, Siraphat, Yaffe, Raz, Caudill, Marie A., Golan, Hava M.“…Changes in major C1 metabolites, such as the ratios between betaine/choline and SAM/SAH in the cerebral-cortex, were associated with ASD-like behavior. …”
Publicado 2019
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14843por Li, Baiyi, Chang, Shaoyan, Liu, Chi, Zhang, Min, Zhang, Lianfeng, Liang, Liang, Li, Rui, Wang, Xiuwei, Qin, Chuan, Zhang, Ting, Niu, Bo, Wang, Li“…Maternal serum folate, 5-methyltetrahydrofolate (5-MeTHF), S-adenosylmethionine (SAM), and S-adenosylhomocysteine (SAH) concentrations and global DNA methylation were assessed by LC/MS/MS method. …”
Publicado 2019
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14844por Gnangnon, Bénédicte, Fréville, Aline, Cailliau, Katia, Leroy, Catherine, De Witte, Caroline, Tulasne, David, Martoriarti, Alain, Jung, Vincent, Guerrera, Ida Chiara, Marion, Sabrina, Khalife, Jamal, Pierrot, Christine“…The sterile alpha motif (SAM) and RVxF motifs of PfpTKL were found to interact with the P. falciparum proteins serine repeat antigen 5 (SERA5) and protein phosphatase type 1 (PP1) respectively, suggesting that pTKL has a scaffolding role. …”
Publicado 2019
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14845por Oerum, Stephanie, Catala, Marjorie, Atdjian, Colette, Brachet, Franck, Ponchon, Luc, Barraud, Pierre, Iannazzo, Laura, Droogmans, Louis, Braud, Emmanuelle, Ethève-Quelquejeu, Mélanie, Tisné, Carine“…RNA methyltransferases (MTases) catalyse the transfer of a methyl group to their RNA substrates using most-often S-adenosyl-L-methionine (SAM) as cofactor. Only few RNA-bound MTases structures are currently available due to the difficulties in crystallising RNA:protein complexes. …”
Publicado 2019
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14846por Yang, Hui, Shi, Guixia, Li, Xiao, Hu, Dezhou, Cui, Yanmei, Hou, Jinfeng, Yu, Deyue, Huang, Fang“…Besides, GmFILa transgenic plants also exhibited longer flowering period and inhibition of shoot apical meristem (SAM) development compared to the wild type plants. …”
Publicado 2019
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14847por Fontanesi, Claudio, Como, Enrico Da, Vanossi, Davide, Montecchi, Monica, Cannio, Maria, Mondal, Prakash Chandra, Giurlani, Walter, Innocenti, Massimo, Pasquali, Luca“…Electroactive self-assembled monolayers (SAMs) bearing a ferrocene (Fc) redox couple were chemically assembled on H-terminated semiconducting degenerate-doped n-type Si(111) substrate. …”
Publicado 2019
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14848por Fuentes-Lara, Laura Olivia, Medrano-Macías, Julia, Pérez-Labrada, Fabián, Rivas-Martínez, Erika Nohemí, García-Enciso, Ema Laura, González-Morales, Susana, Juárez-Maldonado, Antonio, Rincón-Sánchez, Froylán, Benavides-Mendoza, Adalberto“…S(−2) is also the basis of essential biological molecules in signaling, metabolism, and stress tolerance, such as reactive sulfur species (RSS), SAM, glutathione, and phytochelatins. The present review describes the dynamics of sulfur in soil and plants, considering elemental sulfur as the starting point, and, as a final point, the sulfur accumulated as S(−2) in biological structures. …”
Publicado 2019
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14849“…OBJECTIVES: Cultivated wild ginseng (cWG), called SanYangSanSam, has been used clinically in patients with chronic fatigue in Korea. …”
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14850por Banerjee, Shibdas, Wong, Anny Chuu-Yun, Yan, Xin, Wu, Bo, Zhao, Hongjuan, Tibshirani, Robert J., Zare, Richard N., Brooks, James D.“…However, rapid upregulation of PG(22:6/22:6) level appeared to be a hitherto unknown feature of the metabolic shift observed in UUO. Using LASSO and SAM (significance analysis of microarrays), we identified a set of well-measured metabolites that accurately predicted UUO-induced renal damage that was detectable by 12 h after UUO, prior to apparent histological changes. …”
Publicado 2019
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14851por Li, Lulu, Zheng, Tangchun, Zhuo, Xiaokang, Li, Suzhen, Qiu, Like, Wang, Jia, Cheng, Tangren, Zhang, Qixiang“…Protein–protein interaction predictions showed that the subfamily III genes may regulate vascular development and shoot apical meristem (SAM) maintenance. Promoter analysis showed that the HD-Zip III genes might be involved in responses to light, hormones, and abiotic stressors and stem development. …”
Publicado 2019
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14852por Tai, Yanni, Zou, Fuxian, Zhang, Qiurong, Wang, Jia, Rao, Ronghui, Xie, Ruihua, Wu, Shuisheng, Chu, Kedan, Xu, Wen, Li, Xiaoyan, Huang, Mingqing“…Rhizoma Alismatis (RA), widely known as “Ze-Xie” in China, is the tuber of Alisma orientale (Sam.) Juzep (Alismaceae), a Chinese herbal medicine that has been used to treat hyperlipidemia, diabetes, hypertension, dysuria, and inflammation. …”
Publicado 2019
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14853por Grdiša, Martina, Radosavljević, Ivan, Liber, Zlatko, Stefkov, Gjoshe, Ralli, Parthenopi, Chatzopoulou, Paschalina S., Carović-Stanko, Klaudija, Šatović, Zlatko“…The spatial analysis method Samβada detected 50 individual markers (22.12%) associated with bioclimatic variables, among them seven were identified by both Mcheza and BayeScan as being under directional selection. …”
Publicado 2019
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14854por Gong, Mi, Yan, Changsheng, Jiang, Yi, Meng, Huangyang, Feng, Mingming, Cheng, Wenjun“…ALK and LTK ligand 2 was the most downregulated gene associated with the tumor grade, while CCCTC-binding factor like (CTCFL), EGF like domain multiple 6, radical S-adenosyl methionine domain containing 2 and SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 were the most upregulated genes associated with EOC grade. …”
Publicado 2019
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14855por Smits, Nicole W. G., den Boer, Daan, Wu, Longfei, Hofmann, Jan P., Hetterscheid, Dennis G. H.“…To enable covalent attachment of the complex to the gold surface, a heteromolecular self-assembled monolayer (SAM) of butanethiol and a thiol-substituted tmpa ligand was used. …”
Publicado 2019
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14856“…We report here the crystal structure of human N6amt1–Trm112 in complex with cofactor SAM. Structural analysis shows that Trm112 binds to a hydrophobic surface of N6amt1 to stabilize its structure but does not directly contribute to substrate binding and catalysis. …”
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14857“…In addition, LIPCAR significantly decreased α-SAM expression. CONCLUSIONS: Together, our data suggest that overexpression of LIPCAR promotes cell proliferation, migration, and phenotypic switch of vascular smooth muscle cells.…”
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14858por Shepard, Caitlin, Xu, Joella, Holler, Jessica, Kim, Dong-Hyun, Mansky, Louis M., Schinazi, Raymond F., Kim, Baek“…BACKGROUND: Terminally differentiated/nondividing macrophages, a key target cell type of HIV-1, harbor extremely low dNTP concentrations established by a host dNTP triphosphohydrolase, SAM domain and HD domain containing protein 1 (SAMHD1). …”
Publicado 2019
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14859por Mamo, Worku Nigussu, Derso, Terefe, Gelaye, Kassahun Alemu, Akalu, Temesgen Yihunie“…BACKGROUND: Despite the available interventions to tackle nutritional problems, there is scarce information on time to recovery and its determinants among children with SAM in Ethiopia. OBJECTIVE: This study was aimed at finding the time to recovery and determinants among 6–59 months children with severe acute malnutrition treated at an outpatient therapeutic programme in North Gondar zone, northwest Ethiopia. …”
Publicado 2019
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14860“…Similarly, hES cells require methionine (Met) to maintain the Met-SAM (S-adenosyl methionine) cycle of 1-carbon metabolism also for H3K4me3 formation. …”
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