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  1. 121
    “…Subependymal giant cell astrocytoma (SEGA) is a unique brain tumor that constitutes one of the major diagnostic criteria of tuberous sclerosis complex (TSC). …”
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    Late Manifestation of Subependymal Giant Cell Astrocytoma With Hydrocephalus in an Adult Patient With Tuberous Sclerosis Complex
  2. 122
    “…Subependymal giant cell astrocytomas (SEGAs) are the most common intracranial tumors in Tuberous Sclerosis Complex (TSC). …”
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    A solitary extraventricular subependymal giant cell astrocytoma in the absence of tuberous sclerosis
  3. 123
    “…Subependymal giant cell astrocytoma (SEGA) is a slow-growing brain tumor almost exclusively associated with TSC. …”
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    Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex—Current Views on Their Pathogenesis and Management
  4. 124
    “…OBJECTIVE: To analyze the cumulative efficacy and safety of everolimus in treating subependymal giant cell astrocytomas (SEGA) associated with tuberous sclerosis complex (TSC) from an open‐label phase II study (NCT00411619). …”
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    Everolimus for subependymal giant cell astrocytoma: 5‐year final analysis
  5. 125
    “…We investigated the methylation profile of SEGAs using the Illumina Infinium HumanMethylation450 BeadChip (SEGAs n = 42, periventricular control n = 8). …”
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    Distinct DNA Methylation Patterns of Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex
  6. 126
    “…Data of 14 patients were analyzed. SEGA volume (SV) was evaluated at study entry and subsequent time points by an experienced radiologist. …”
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    Maintenance Therapy With Everolimus for Subependymal Giant Cell Astrocytoma in Patients With Tuberous Sclerosis – Final Results From the EMINENTS Study
  7. 127
    “…Subependymal giant cell astrocytomas (SEGAs) are circumscribed gliomas strongly associated with tuberous sclerosis (TS). …”
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    LGG-49. Subependymal giant cell astrocytoma associated with a cortical tuber: A case report
  8. 128
    “…The Everolimus For Fast Expanded aCcess in TSC SEGA (EFFECTS) study was designed to provide everolimus access to patients with SEGA associated with TSC and to mainly assess the safety and also efficacy of everolimus in a real-world setting. …”
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    EFFECTS: an expanded access program of everolimus for patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex
  9. 129
    “…Patients aged 65 years and up were screened for frailty using the modified SEGA (mSEGA) assessment, and physical activity was measured using the Ricci–Gagnon questionnaire. …”
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    Physical Activity in the Elderly and Frailty Syndrome: A Retrospective Study in Primary Care
  10. 130
    “…In the CNS, TSC is characterized by cortical tubers, subependymal nodules and subependymal giant cell astrocytomas (SEGAs). SEGAs may lead to impaired circulation of CSF resulting in hydrocephalus and raised intracranial pressure in patients with TSC. …”
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    The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas
  11. 131
    “…Subependymal giant cell astrocytoma (SEGA) occurs in 10-15% of TSC patients. Routine brain surveillance is important to look for SEGA in all TSC patients. …”
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    LINC-13. Subependymal giant cell astrocytoma in a child with tuberous sclerosis complex: a case report
  12. 132
    “…Herein, an ultra-compressible ternary composite was synthesized by successively electrodepositing poly(3,4-ethylenedioxythiophene) (PEDOT) and MnO(2) into the superelastic graphene aerogel (SEGA). In SEGA/PEDOT/MnO(2) ternary composite, SEGA provides the compressible backbone and conductive network; MnO(2) is mainly responsible for pseudo reactions; the middle PEDOT not only reduces the interface resistance between MnO(2) and graphene, but also further reinforces the strength of graphene cellar walls. …”
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    Superelastic Graphene Aerogel/Poly(3,4-Ethylenedioxythiophene)/MnO(2) Composite as Compression-Tolerant Electrode for Electrochemical Capacitors
  13. 133
    “…Reasons for initiation of treatment were cardiac rhabdomyomas (6 cases), subependymal giant cell astrocytomas (SEGA, 5 cases), combination of cardiac rhabdomyomas and SEGA (1 case), refractory epilepsy (4 cases) and disabling congenital focal lymphedema (1 case). …”
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    Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age – a multicenter retrospective study
  14. 134
    “…Subependymal giant cell astrocytoma (SEGA) is a rare, slow-growing tumor with a dual (neuroglial) component that is typically associated with tuberous sclerosis complex (TSC). …”
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    Subependymal Giant Cell Astrocytoma Non-Associated With Tuberous Sclerosis Complex and Expression of OCT-4 and INI-1: A Case Report
  15. 135
    “…RESULTS: The SEGA score was inversely correlated with MMSE, MNA and Katz score. …”
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    Prevalence and factors associated with frailty in hospitalized older patients
  16. 136
    “…We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). …”
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    Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report
  17. 137
    “…In this study, we reviewed the clinical characteristics of five cases of subependymal giant cell astrocytoma (SEGA) at our hospital between May 1997 and July 2012. …”
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    The Clinical Characteristics of Subependymal Giant Cell Astrocytoma: Five Cases
  18. 138
    “…Finally, GCLC inhibition led to growth arrest and death of SEGA-derived cells. CONCLUSIONS: We describe GCLC as a part of redox adaptation in TSC, needed for overgrowth and survival of mutant cells, and provide a potential novel target for SEGA treatment. …”
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    Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase
  19. 139
    “…This shows that everolimus is active on MMPH similarly to its effects on SEGA, renal angiomyolipomas, and pulmonary lymphangioleiomyomatosis in TSC, and suggests that the dysregulated activation of mTOR which characterizes TSC also plays a role in the pathogenesis of MMPH.…”
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    Effect of everolimus on multifocal micronodular pneumocyte hyperplasia in tuberous sclerosis complex
  20. 140
    “…Subependymal giant cell astrocytomas (SEGAs) are histologically benign tumors most frequently associated with tuberous sclerosis complex (TSC). …”
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    Subependymal Giant Cell Astrocytoma: Associated Hyperproteinorrhachia Causing Shunt Failures and Nonobstructive Hydrocephalus - Report of Successful Treatment with Long-term Follow-up
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