-
141por Karagianni, Aikaterini, Karydakis, Ploutarchos, Giakoumettis, Dimitrios, Nikas, Ioannis, Sfakianos, George, Themistocleous, Marios“…BACKGROUND: Subependymal giant cell astrocytomas (SEGAs) appear approximately in 10% of patients with tuberous sclerosis. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
142por Zulfiqar, Abrar-Ahmad“…Objective: To evaluate the performance of the “ZFS” tool to screen for frailty as defined SEGA scale criteria in an ambulatory population of patients at least 65 years of age. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
143por Ghani, Imran, Patel, Sabina, Ghimire, Prajwal, Bodi, Istvan, Bhangoo, Ranjeev, Vergani, Francesco, Ashkan, Keyoumars, Lavrador, Jose Pedro“…Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
144por Sasongko, Teguh Haryo, Ismail, Nur Farrah Dila, Nik Abdul Malik, Nik Mohamad Ariff, Zabidi-Hussin, Z. A. M. H.“…Five patients from the case reports (all with SEGA) and 91 patients from the clinical trials (41 with SEGA, 63 with kidney angiomyolipoma and 5 with liver angiomyolipoma) were included into the analysis. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
145por Vergeer, Menno, de Ranitz‐Greven, Wendela L., Neary, Maureen P., Ionescu‐Ittu, Raluca, Emond, Bruno, Sheng Duh, Mei, Jansen, Floor, Zonnenberg, Bernard A.“…HRQoL data were assessed in 2012 using the Health Utility Index version 3 (HUI‐3) questionnaire completed by patients or caregivers (N = 214 with HUI score and ≥1 TSC manifestation, including renal angiomyolipomas [rAMLs], subependymal giant cell astrocytoma [SEGA], or epilepsy). RESULTS: Of 214 patients in the study sample, 171 had TSC‐associated epilepsy (with or without rAML/SEGA), 37 had TSC and rAML (without epilepsy or SEGA), and 6 had other combinations of manifestations. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
146“…Frailty was evaluated using three scales: the Fried scale, the CFS and the modified SEGA scale. Results: A total of 359 patients were included, comprising 251 women (70%) with an average age of 85.28 years. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
147por De Meulemeester, Ann-Sofie, Heylen, Lise, Siekierska, Aleksandra, Mills, James D., Romagnolo, Alessia, Van Der Wel, Nicole N., Aronica, Eleonora, de Witte, Peter A. M.“…In particular, the transcriptome of human SEGA lesions overlapped strongly with the double homozygous zebrafish larvae. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
148“…PARTICIPANTS: 48 Italian caregivers, assisting patients with TSC with SEGA manifestation have been involved in the study. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
149por Habib, Samy L, Al-Obaidi, Noor Y, Nowacki, Maciej, Pietkun, Katarzyna, Zegarska, Barbara, Kloskowski, Tomasz, Zegarski, Wojciech, Drewa, Tomasz, Medina, Edward A., Zhao, Zhenze, Liang, Sitai“…Particularly problematic are the development of renal angiomyolipomas, which tend to be larger, bilateral, multifocal and present at a younger age compared with sporadic forms. In addition, SEGA block the flow of fluid within the brain, causing a buildup of fluid and pressure that leads to blurred vision and seizures. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
150por Rambabova Bushljetik, I, Lazareska, M, Barbov, I, Stankov, O, Filipce, V, Spasovski, G“…A reduction of the total size of SEGA was also observed. The most common adverse effect of treatment was stomatitis grades 3 to 4 and one febrile episode associated with skin rash that required a reduced dose of EVE. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
151The metformin in tuberous sclerosis (MiTS) study: A randomised double-blind placebo-controlled trialpor Amin, Sam, Mallick, Andrew A, Edwards, Hannah, Cortina-Borja, Mario, Laugharne, Matthew, Likeman, Marcus, O'Callaghan, Finbar J.K.“…Twenty-seven patients had SEGAs: 13 received placebo and 14 metformin. The median percentage change in SEGA volume was +3.0% (IQR -22.8% to +27.7%) for the placebo group and – 20.8% (IQR – 47.1% to - 5.0%) for the metformin group (p = 0.03). …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
152
-
153por Takayanagi, Shunsaku, Takami, Hirokazu, Tanaka, Shota, Shin, Masahiro, Saito, Nobuhito“…METHODS: Seven cases of intraventricular tumors without ventriculomegaly (5 cases of subependymal giant cell astrocytoma (SEGA) and 2 cases of germ cell tumors (GCTs)) were analyzed. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
154por Zulfiqar, Abrar-Ahmad“…The percentage of frail subjects was 63.7% in our scale, 67.7% in the mSEGA grid A, 75.5% in the GFST, and 60.8% for the Fried criteria. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
155por Wang, Shihao, Zhang, Jianxiong, Ding, Xuefeng, Hu, Dasha, Wang, Baojian, Guo, Bing, Tang, Jun, Du, Ke, Tang, Chao, Jiang, Yuming“…The comparative experiment results of SGA, SEGA (strengthen elitist genetic algorithm), ERGA, and the analysis of the population evolution process show that ERGA is superior to SGA and SEGA in terms of time cost and optimization results through the reasonable combination of coding methods and selection operators. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
156por Cockerell, Ine, Christensen, Jakob, Hoei-Hansen, Christina E., Holst, Lotte, Grenaa Frederiksen, Mikkel, Issa-Epe, Aart Imran, Nedregaard, Bård, Solhoff, Ragnar, Heimdal, Ketil, Johannessen Landmark, Cecilie, Lund, Caroline, Nærland, Terje“…As with EXIST, everolimus reduced or stabilised rAML size in most patients. SEGA volume was reduced in all three patients. Close follow-up is needed for this group, especially for children and patients who may not be able to report adverse effects. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
157por Sabus, Ashley, Winzent, Shelby, Hemenway, Molly, Levy, Jean Mulcahy, Foreman, Nicholas“…METHODS: Investigators conducted a retrospective review of neuro-oncology patients with TSC and SEGA who were treated concurrently with everolimus and cannabidiol. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
158por Samueli, Sharon, Abraham, Klaus, Dressler, Anastasia, Gröppel, Gudrun, Mühlebner-Fahrngruber, Angelika, Scholl, Theresa, Kasprian, Gregor, Laccone, Franco, Feucht, Martha“…The mTOR-Inhibitor Everolimus (Votubia®) was approved for the treatment of subependymal giant cell astrocytoma (SEGA) and renal angiomyolipoma (AML) in Europe in 2011. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
159por Bissler, John J, Budde, Klemens, Sauter, Matthias, Franz, David N, Zonnenberg, Bernard A, Frost, Michael D, Belousova, Elena, Berkowitz, Noah, Ridolfi, Antonia, Christopher Kingswood, J“…Patients in EXIST-1 had TSC and subependymal giant cell astrocytoma (SEGA), and patients in EXIST-2 had renal angiomyolipoma and a definite diagnosis of TSC or sporadic lymphangioleiomyomatosis. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
160por Andrews, Lily J, Thornton, Zak A, Saincher, Saanwalshah S, Yao, Ian Y, Dawson, Sarah, McGuinness, Luke A, Jones, Hayley E, Jefferies, Sarah, Short, Susan C, Cheng, Hung-Yuan, McAleenan, Alexandra, Higgins, Julian P T, Kurian, Kathreena M“…CONCLUSIONS: BRAFV600 prevalence is highest in eGBM, PXA, aPXA, GG, aGG, and lower in astroblastoma, DIA, SEGA, DNET, DA, and PA. Our data provide the rationale for adjuvant clinical trials of BRAFi in V600-mutant glioma.…”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto