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Mostrando 161 - 180 Resultados de 200 Para Buscar '"SEGA"', tiempo de consulta: 0.33s Limitar resultados
  1. 161
    “…GAB Aergics were the most prescribed drugs for epilepsy, and mTOR inhibitors are dramatically replacing surgery in patients with SEGA, despite current recommendations proposing both treatment options. mTOR inhibitors are also becoming common treatments in rAML and LAM patients. …”
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    Treatment Patterns and Use of Resources in Patients With Tuberous Sclerosis Complex: Insights From the TOSCA Registry
  2. 162
    “…The purpose of this paper is to discuss the importance of organizations that work with children exposed to maltreatment, highlight the novel approach of Child Advocacy Services, SEGA, Inc. (CASSEGA), the sponsoring agency for Court Appointed Special Advocates (CASA) and the Ogeechee Visitation Centers, in rural southeast Georgia and how the COVID-19 pandemic has challenged this work, and develop strategies that can be put into place to alleviate these challenges for other child-serving organizations.…”
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    Child Victim Services in the Time of COVID-19: New Challenges and Innovative Solutions
  3. 163
    “…Everolimus, an mTOR inhibitor, has been FDA-approved for subependymal giant cell astrocytomas (SEGAs) and renal angiomyolipomas in TSC. However, clinical use of everolimus with direct, real-time observations of self-injury and aggression in an individual with TSC has not been reported. …”
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    Everolimus and intensive behavioral therapy in an adolescent with tuberous sclerosis complex and severe behavior()()()
  4. 164
    por Isaacs, Hart
    Publicado 2016
    “…Glioblastoma (GBM) was the most common neoplasm followed in order by subependymal giant cell astrocytoma (SEGA), low-grade astrocytoma, anaplastic astrocytoma, and desmoplastic infantile astrocytoma (DIA). …”
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    Perinatal (fetal and neonatal) astrocytoma: a review
  5. 165
    “…Other differentials include subependymal giant cell astrocytoma (SEGA), ependymoma, meningioma, and low-grade gliomas such as pilocytic or diffuse astrocytoma; calcification is more commonly regarded as a feature of benign or slow-growing tumors. …”
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    Pilocytic astrocytoma: A rare presentation as intraventricular tumor
  6. 166
    “…Here we find the features of TDP-43 fibrils that confer both reversibility and irreversibility by determining structures of two segments reported to be the pathogenic cores of human TDP-43 aggregation: SegA (residues 311–360), which forms three polymorphs, all with dagger-shaped folds; and SegB A315E (residues 286–331 containing the ALS hereditary mutation A315E), which forms R-shaped folds. …”
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    Cryo-EM Structures of Four Polymorphic TDP-43 Amyloid Cores
  7. 167
    “…Owing to the out-of-plane symmetry being broken, the BP/Ga(2)SSe vdWHs are divided into two different stacking patterns, which are BP/SGa(2)Se and BP/SeGa(2)S. Our results demonstrate that these stacking patterns are structurally and mechanically stable. …”
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    Electronic structure and interface contact of two-dimensional van der Waals boron phosphide/Ga(2)SSe heterostructures
  8. 168
    “…Subependymal giant cell astrocytoma (SEGA) identified by regular neuroimaging examinations remained unchanged, which may be a consequence of early intrauterine treatment. …”
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    Three-Year Follow-Up after Intrauterine mTOR Inhibitor Administration for Fetus with TSC-Associated Rhabdomyoma
  9. 169
    “…The mTOR inhibitor everolimus is indicated for the treatment of adult TSC patients with renal angiomyolipomas (AMLs) and for subependymal giant astrocytoma (SEGA) in both adults and children, based on data from the EXIST-1 and EXIST-2 trials. …”
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    Management of everolimus-associated adverse events in patients with tuberous sclerosis complex: a practical guide
  10. 170
    por Pham, Khang D.
    Publicado 2022
    “…The out-of-plane symmetry in the Janus Ga(2)SSe monolayer leads to the formation of two different types of Ga(2)SSe/SiH heterostructure, namely SGa(2)Se/SiH and SeGa(2)S/SiH stacking patterns. All stacking patterns of the SiH/Ga(2)SSe heterostructure are thermodynamically, mechanically and energetically stable at room temperature. …”
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    First principles prediction of electronic, mechanical, transport and optical properties of the silicane/Ga(2)SSe heterostructure
  11. 171
    “…INTRODUCTION: Everolimus is an inhibitor of mTORC1 (mammalian target of rapamycin complex 1), it is Health Canada and FDA approved for SEGA and renal angiomyolipoma in the setting of tuberous sclerosis complex (TSC). …”
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    RARE-25. RETINAL ASTROCYTOMA mTOR INHIBITOR THERAPY IN TUBEROUS SCLEROSIS MOSAICISM
  12. 172
    “…Furthermore, everolimus treatment showed not only reduction in SEGA size, but dramatically improved behavioral deficits including autism related behaviors in the patient. …”
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    Everolimus improves neuropsychiatric symptoms in a patient with tuberous sclerosis carrying a novel TSC2 mutation
  13. 173
    “…METHODS: This was a post hoc analysis of pediatric patients being treated for subependymal giant cell astrocytomas (SEGAs) during the phase 3, randomized, double-blind, placebo-controlled EXIST-1 trial. …”
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    The effect of everolimus on renal angiomyolipoma in pediatric patients with tuberous sclerosis being treated for subependymal giant cell astrocytoma
  14. 174
    “…These gene products form a protein complex and normally suppress mammalian target of rapamycin (mTOR) activity. mTOR inhibitors have been used to treat subependymal glioma (SEGA) that is a brain tumor characteristic of TSC. …”
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    Multiple Critical Periods for Rapamycin Treatment to Correct Structural Defects in Tsc-1-Suppressed Brain
  15. 175
    “…[TSC] Recently, the use of Afinitor for SEGA was covered by insurance in Japan, and a system in which multiple departments involved in our hospital cooperated was established, and regular meetings were held to determine treatment policies. …”
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    COT-07 HEREDITARY BRAIN TUMOR DISEASE MEDICINE IN THE CANCER GENOME MEDICAL AGE-IMPORTANCE OF MULTIDISCIPLINARY COLLABORATION AND GENETIC COUNSELING
  16. 176
    por Orduña, Patricia
    Publicado 2020
    “…Subependymal giant cell astrocytomas (SEGA) may lead to significant neurological morbidity in children diagnosed with tuberous sclerosis complex (TSC). …”
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    LINC-17. SIROLIMUS AS AN ALTERNATIVE TO SURGICAL RESECTION OF PEDIATRIC TUBEROUS SCLEROSIS COMPLEX-ASSOCIATED BILATERAL SUBEPENDYMAL GIANT CELL ASTROCYTOMAS: AN AFFORDABLE OPTION FOR PATIENTS FROM LOW-MIDDLE INCOME COUNTRIES
  17. 177
    “…METHODS: The MLC parameters (leaf transmission and leaf offset) of the treatment planning system were adjusted by evaluating seven plans (10 × 10 cm, 3ABUT, DMLC, 7segA, FOURL, HDMLC, and HIMRT) and 20 preclinical cases (10 cases each in 4- and 6-MV groups). …”
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    Adjustment of multi-leaf collimator parameters in 4-MV and 6-MV IMRT: A study of veterinary clinical cases
  18. 178
    “…In our series, there was a statistically strong link between the risk of falling and the presence of a dementia pathology (p = 0.009), the presence of a vitamin D deficiency (p = 0.03), the presence of frailty, as assessed by the three scales (modified SEGA scale, Fried scale and CFS/7 (<0.001), a high comorbidity score (p = 0.04), and a disturbed autonomy assessment according to IADL (p = 1.02 × 10(−5)) and according to ADL (p = 6.4 × 10(−8)). …”
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    Association of Frailty Status with Risk of Fall among Hospitalized Elderly Patients: A Cross-Sectional Study in an Acute Geriatric Unit
  19. 179
    “…Here, we sought to evaluate the potential of gaboxadol (also called OV101 and THIP), a selective and potent agonist for delta-subunit-containing extrasynaptic GABA(A) receptors (dSEGA), as a therapeutic agent for FXS by assessing its ability to normalize aberrant behaviors in a relatively uncharacterized mouse model of FXS (Fmr1 KO2 mice). …”
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    Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome
  20. 180
    “…Patient tumor types included: germ cell tumor (n = 26); medulloblastoma (n = 16); pilocytic astrocytoma (n = 8); glioblastoma (n = 8); ependymoma (n = 6,1 with grade 2,5 with grade 3); hemangioblastoma,schwannoma,and ganglioglioma (n = 3 each); SEGA,pilomyxoid astrocytoma,and diffuse astrocytoma (n = 2 each),and anaplastic astrocytoma,PPTID,PNET,PXA,DIA,central neurocytoma,astroblastoma,meningioma,and choroid plexus papilloma (n = 1 each). …”
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    COT-14 CLINICAL FEATURES OF PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS
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