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161por Ku, Kyung-Eun, Choi, Nahyun, Oh, Sang-Ho, Kim, Won-Serk, Suh, Wonhee, Sung, Jong-Hyuk“…The Src kinase family (SKF) includes non-receptor tyrosine kinases that interact with many cellular cytosolic, nuclear and membrane proteins, and is involved in the progression of cellular transformation and oncogenic activity. …”
Publicado 2019
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162por Wester, Michael, Heller, Anton, Gruber, Michael, Maier, Lars S., Schach, Christian, Wagner, Stefan“…Interestingly, these Dex-dependent effects could be abolished in the presence of SOCE-inhibitors SKF-96356 (SKF, 2 μM) and BTP2 (5 μM). Ca transient kinetics (time to peak, decay time) were not affected by SOCE stimulation. …”
Publicado 2019
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163por Darvish-Ghane, Soroush, Quintana, Clémentine, Beaulieu, Jean-Martin, Martin, Loren J.“…Further, the D1R high-efficacy agonist SKF 81297 and low efficacy agonist (±)-SKF-38393 inhibit α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic receptor (AMPAR) currents in the ACC. …”
Publicado 2020
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164por Engler, Ian D., Salzler, Matthew J., Wall, Andrew J., Johnson, William R., Makani, Amun, Shields, Margaret V., Gill, Thomas J.“…Patients completed the International Knee Documentation Committee Subjective Knee Evaluation Form (IKDC-SKF) and Tegner Activity Level Scale. Patients who had outcomes scores completed a minimum of 2 years postoperatively were included. …”
Publicado 2020
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165“…MATERIALS AND METHODS: The SKF38393 and eticlopride, individually and simultaneously (in ineffective doses), were injected into the pVTA with the AP5 in rats, and animals were then placed in a CPP apparatus. …”
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166“…To address the role of activity in Nr4a1-eGFP expression, primary striatal cultures were prepared from neonatal mice and treated with forskolin, BDNF, SKF-83822 or high extracellular potassium and eGFP was measured fluorometrically in lysates. eGFP was induced in both neurons and contaminating glia in response to forskolin but SKF-83822, brain derived neurotrophic factor and depolarization increased eGFP in neuronal-like cells selectively. …”
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167por Zappettini, Stefania, Grilli, Massimo, Lagomarsino, Federica, Cavallero, Anna, Fedele, Ernesto, Marchi, Mario“…Additionally, 5-Iodo-A-85380 dihydrochloride (5IA85380) elicited GABA overflow, which was Ca(2+) dependent, blocked by Cd(2+), and significantly inhibited by TTX and DHβE, but unaffected by MLA, SKF 89976A, thapsigargin and xestospongin C and dantrolene. …”
Publicado 2011
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168por Bystrom, Jonas, Wray, Jessica A., Sugden, Mary C., Holness, Mark J., Swales, Karen E., Warner, Timothy D., Edin, Matthew L., Zeldin, Darryl C., Gilroy, Derek W., Bishop-Bailey, David“…The suppression of TNFα by SKF525A in the presence of IL-4 was associated with a reduction in superoxide anion generation and reproduced by the superoxide dismutase MnCl(2). …”
Publicado 2011
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169por Busceti, Carla Letizia, Bucci, Domenico, Molinaro, Gemma, Di Pietro, Paola, Zangrandi, Luca, Gradini, Roberto, Moratalla, Rosario, Battaglia, Giuseppe, Bruno, Valeria, Nicoletti, Ferdinando, Fornai, Francesco“…Treatment with the D1-like receptor agonist SKF38393 (10 mg/kg) or with the D2-like receptor agonist, quinpirole (1 mg/kg) did not change the number of TH(+) neurons. …”
Publicado 2012
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170“…OBJECTIVE: To determine the correlation between dual energy X-ray absorptiometry (DEXA) and skin fold thickness (SKF) equations for estimation of body fat (BF) composition in secondary school children and validation of prediction equations by Slaughter, Goran and Dezenberg. …”
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171por Gildea, John J., Shah, Ishan T., Van Sciver, Robert, Israel, Jonathan A., Enzensperger, Christoph, McGrath, Helen E., Jose, Pedro A., Felder, Robin A.“…Further studies using the cAMP-selective D(1)R/D(5)R agonist SKF83822 and PLC-selective D(1)R/D(5)R agonist SKF83959 confirmed the cooperative influence of the two pathways on sodium transport. …”
Publicado 2014
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172“…Activation of D(1)-like receptors using SKF38393, SKF83959, or 1 µM dopamine induced a reversible facilitation of EPSCs which was abolished by loading cells with either the phospholipase C inhibitor U-73122 or the Ca(2+) chelator BAPTA. …”
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173por Zhang, Tingting, Chen, Tingting, Chen, Peipei, Zhang, Baofeng, Hong, Juan, Chen, Ling“…Decline of PKC phosphorylation in BLA of MPTP-mice was corrected by bath-application of quinpirole, but not SKF38393. In MPTP-mice, BLA-injection of quinpirole or PKC activator PMA could recover GABA(A)R expression, which was sensitive to PKC inhibitor GF109203X. …”
Publicado 2017
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174Rapid coupling between gravitational forces and the transcriptome in human myelomonocytic U937 cellspor Thiel, Cora S., Tauber, Svantje, Christoffel, Swantje, Huge, Andreas, Lauber, Beatrice A., Polzer, Jennifer, Paulsen, Katrin, Lier, Hartwin, Engelmann, Frank, Schmitz, Burkhard, Schütte, Andreas, Raig, Christiane, Layer, Liliana E., Ullrich, Oliver“…Experiments with the wide range ion channel inhibitor SKF-96365 in combination with whole transcriptome analysis were conducted to study the functional role of ion channels in the transduction of gravitational forces at an integrative level. …”
Publicado 2018
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175por Ha, Jeong Ku, Kim, Jin Goo, Yoon, Kyoung Ho, Wang, Joon Ho, Seon, Jong Keun, Bae, Ji Hoon, Jang, Ki Mo“…Construct validity assessed by correlation analysis with KOOS, IKDC-SKF, and Lysholm scale showed the correlation coefficients ranging from 0.169 to 0.679 (all p < 0.01). …”
Publicado 2019
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176“…Demographic information, activity participation, International Knee Documentation Committee subjective knee form (IKDC-SKF) and the Single Assessment Numeric Evaluation (SANE) score were collected. …”
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177“…Furthermore, knockdown or antagonist (with SKF-96365) of TRPV2 significantly decreased the release of cytokines that drive the inflammatory response. …”
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178por Rozinthe, Anouk, Demey, Guillaume, Van Rooij, Floris, Saffarini, Mo, Dejour, David“…The analysis was based on IKDC-SKF and Lysholm scores, and radiographic analysis. …”
Publicado 2022
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179“…The agonists did not have any significant effect on approach latencies and the proportion of Go responses in the spatial judgment task, as compared to the saline control, except for 10.0 mg/kg SKF 38393, which caused a decrease in the proportion of Go responses. …”
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180por Martin, Yvonne Connolly“…The novel selective D1 dopaminergic full agonists A-68930, A-77636 were discovered by the synthesis of molecules to probe the bioactive conformation of the partial agonist SKF-38393, by the use of this information to add D1 affinity and selectivity to a screening hit, and by traditional medicinal chemistry exploration of structure-activity relationships. …”
Publicado 2011
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