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3por Miller, Brad, Marks, Lauren A., Koller, Jonathan M., Newman, Blake J., Bretthorst, G. Larry, Black, Kevin J.“…Time course studies charted the changes in plasma prolactin levels over time after anesthesia alone or after an intravenous (i.v.) dose of the dopamine D(1)-like agonists SKF82958 and SKF38393 or the D(2)-like agonist pramipexole. …”
Publicado 2013
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4por Cheng, Huijun, Li, Jiaoxia, Wu, Qiyan, Zheng, Xiaodong, Gao, Yongqiang, Yang, Qiaofen, Sun, Ningxi, He, Meiqiong, Zhou, Youjun“…The aim of the present study was to investigate the role of the TRPC channel inhibitor SKF-96365 in cardiomyocyte hypertrophy induced by Ang II and the potential mechanisms of SKF-96365. …”
Publicado 2020
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5por Torrezan-Nitao, Elis, Brown, Sean G, Lefievre, Linda, Morris, Jennifer, Correia, Joao, Harper, Claire V, Publicover, Stephen“…We investigated the potential significance of store-operated Ca(2+)-entry in these oscillations using the inhibitor SKF96365 (30 µM; SKF). Following pre-treatment of human sperm with 3 µM P4, exposure to SKF doubled the proportion of oscillating cells (P = 0.00004). …”
Publicado 2023
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6“…INTRODUCTION: SKF-96365 is regarded as an inhibitor of receptor-mediated calcium ion (Ca(2+)) entry. …”
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7por Wang, Qiru, #, Zhang, Yang, #, Du, Qiong, Zhao, Xinjie, Wang, Wei, Zhai, Qing, Xiang, Ming“…Intrathecal injection of SOCE antagonist SKF96365 dose-dependently alleviated mechanical allodynia in ipsilateral hind paws of neuropathic rats with ED(50) of 18 μg. …”
Publicado 2023
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8por Kümmel, Danica, Preiss, Stefan, Harder, Laurent P., Leunig, Michael, Impellizzeri, Franco M.“…PURPOSE: To examine the measurement properties of the German International Knee Documentation Committee Subjective Knee Form (IKDC-SKF) in knee disorder patients. METHODS: Three hundred twelve consecutive patients undergoing surgery for anterior cruciate ligament, meniscus and/or cartilage injuries completed the IKDC-SKF, Lysholm Score, Tegner Activity Scale, and Short Form-12 Health Survey before and 6 months post-surgery. …”
Publicado 2018
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9“…In the schemes of LOOCV and [Formula: see text]-fold CV, AUC values of SKF-LDA achieve [Formula: see text] and [Formula: see text] respectively. …”
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10“…DDA-SKF integrated multiple similarities of drugs and diseases. …”
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11“…In this paper, we propose an accurate method, MDA-SKF, to uncover potential miRNA-disease associations. …”
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12“…We named this method the LPI-SKF. Various similarities of both lncRNAs and proteins were integrated into the LPI-SKF. …”
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13por TANAHASHI, Yasuyuki, WANG, Ban, MURAKAMI, Yuri, UNNO, Toshihiro, MATSUYAMA, Hayato, NAGANO, Hiroshi, KOMORI, Seiichi“…In order to investigate the effects of SKF96365 (SKF), which is a non-selective cationic channel blocker, on K(+) channel currents, we recorded currents through ATP sensitive K(+) (I(KATP)), voltage-gated K(+) (I(Kv)) and Ca(2+) activated K(+) channels (I(BK)) in the absence and presence of SKF in single small intestinal myocytes of mice with patch-clamp techniques. …”
Publicado 2015
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14“…SKF83959 (10–100 µM) caused a concentration-dependent depolarization, associated with a reduction of input resistance in CA1 pyramidal neurons. …”
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15“…The hyperpolarization‐activated current, I (f), was unaffected by SKF‐96365. Collectively, these results indicate that SKF‐96365 exerts a moderate inhibitory effect on I (B,Na) and slows AVN cell pacemaking. …”
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16por Song, Min, Do, HyunHee, Kwon, Oh Kwang, Yang, Eun-Ju, Bae, Jong-Sup, Jeong, Tae Cheon, Song, Kyung-Sik, Lee, Sangkyu“…Our findings indicate that thelephoric acid may be a novel, non-specific CYP inhibitor, suggesting that it could replace SKF-525A in inhibitory studies designed to investigate the effects of CYP enzymes on the metabolism of given compounds.…”
Publicado 2014
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17por Zhang, Jinyan, Wei, Jiazhang, He, Qian, Lin, Yan, Liang, Rong, Ye, Jiaxiang, Zhang, Zhe, Li, Yongqiang“…We further elucidated the antitumor activity of SKF96365 in xenograft-bearing mice. RESULTS: It was found that SKF96365 disturbed the thapsigargin (TG)-stimulated Ca(2+) release from endoplasmic reticulum and the subsequent Ca(2+) influx. …”
Publicado 2015
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18por Guo, Qing-Yun, Ebihara, Ken, Shimodaira, Takafumi, Fujiwara, Hironori, Toume, Kazufumi, Dibwe, Dya Fita, Awale, Suresh, Araki, Ryota, Yabe, Takeshi, Matsumoto, Kinzo“…We previously demonstrated that a selective type I 5α-reductase inhibitor SKF105111 (SKF) induced ASD-like behaviors, such as impaired sociability-related performance and repetitive grooming behaviors, in male mice. …”
Publicado 2019
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19“…The SKF3833 stimulatory effect persisted over 2 h post-injection. …”
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20“…The present study examined the effects of SKF83959 on operant behaviors and assayed the neurochemical mechanisms involved. …”
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