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1por Fimlaid, Kelly A., Jensen, Owen, Donnelly, M. Lauren, Siegrist, M. Sloan, Shen, Aimee“…In this study, we investigated the requirements of the SpoIIQ and SpoIIIA proteins during C. difficile sporulation. …”
Publicado 2015
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2The Structure and Interactions of SpoIISA and SpoIISB, a Toxin-Antitoxin System in Bacillus subtilispor Florek, Patrik, Levdikov, Vladimir M., Blagova, Elena, Lebedev, Andrey A., Škrabana, Rostislav, Rešetárová, Stanislava, Pavelčíková, Pamela, Barak, Imrich, Wilkinson, Anthony J.“…Inappropriate spoIISA expression causes lysis of vegetatively growing B. subtilis cells and Escherichia coli cells when expressed heterologously, effects that are countered by co-expression of spoIISB, identifying SpoIISA-SpoIISB as a toxin-antitoxin system. …”
Publicado 2011
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3“…Additionally, similar to SPO71, loss of SPO73 partially suppresses spo1Δ. …”
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4“…Diauxic shifts experiments were performed with strains containing SpoT hydrolase and either RelA or SpoT synthetase as the sole source of ppGpp. …”
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5“…We used a spoV mutant in isolate MGAS315 to assess the contribution of the SpoV peptide to virulence by using a murine model of invasive disease and an ex vivo human model (Lancefield assay). …”
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7“…Toward the global understanding of plant meiosis, it seems to be essential to decipher why all as yet sequenced plants need or at least encode for two different meiotic SPO11 genes. This is in contrast to mammals and fungi, where only one SPO11 is present. …”
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8por Chen, Meng, Lyu, Yufei, Feng, Erling, Zhu, Li, Pan, Chao, Wang, Dongshu, Liu, Xiankai, Wang, Hengliang“…Moreover, levels of spoIIE mRNA were reduced in the spoVG mutant, as demonstrated using β-galactosidase activity assays. …”
Publicado 2020
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9por Wang, Yan, Vischer, Norbert O. E., Wekking, Demi, Boggian, Alessandra, Setlow, Peter, Brul, Stanley“…However, the movement dynamics of SpoVAEa in B. cereus spores, and the behavior of the germinosome upon B. cereus spore germination, are not known. …”
Publicado 2022
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10por Shingu, Yoshinori, Tokai, Takeshi, Agawa, Yasuo, Toyota, Kentaro, Ahamed, Selina, Kawagishi-Kobayashi, Makiko, Komatsu, Akira, Mikawa, Tsutomu, Yamamoto, Masa-Toshi, Wakasa, Kyo, Shibata, Takehiko, Kusano, Kohji“…The DSB activity of SPO11 was shown by genetic analyses, but whether SPO11 exerts DSB-forming activity by itself is still an unanswered question. …”
Publicado 2012
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11por Serrano, Mónica, Crawshaw, Adam D., Dembek, Marcin, Monteiro, João M., Pereira, Fátima C., Pinho, Mariana Gomes, Fairweather, Neil F., Salgado, Paula S., Henriques, Adriano O.“…SpoIIQ and SpoIIQ(H120S) interact with SpoIIIAH throughout engulfment. …”
Publicado 2016
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12por Huang, Qiubin, Zhang, Zhen, Liu, Qing, Liu, Fengying, Liu, Yupeng, Zhang, Juanmei, Wang, Gang“…The transcription levels of two genes closely related to biofilm-formation, sipW and calY, were downregulated in a ΔspoVG mutant. The role of SpoVG in regulating biofilm formation was further explored by deleting the genes abrB and sinR in the ΔspoVG mutant, respectively, generating the double mutant strains ΔspoVGΔabrB and ΔspoVGΔsinR. …”
Publicado 2021
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13por Vega-Cabrera, Luz Adriana, Guerrero, Adán, Rodríguez-Mejía, José Luis, Tabche, María Luisa, Wood, Christopher D., Gutiérrez-Rios, Rosa-María, Merino, Enrique, Pardo-López, Liliana“…Our work paves the way for re-evaluation of the role of Spo0M in bacterial cell.…”
Publicado 2017
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14por Fitzsimmons, Liam F., Liu, Lin, Kant, Sashi, Kim, Ju-Sim, Till, James K., Jones-Carson, Jessica, Porwollik, Steffen, McClelland, Michael, Vazquez-Torres, Andres“…In Salmonella, these nucleotide alarmones are generated by the synthetase activities of RelA and SpoT proteins. In addition, the (p)ppGpp hydrolase activity of the bifunctional SpoT protein is essential to preserve cell viability. …”
Publicado 2020
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15por Claeys Bouuaert, Corentin, Tischfield, Sam E., Pu, Stephen, Mimitou, Eleni P., Arias-Palomo, Ernesto, Berger, James M., Keeney, Scott“…Spo11, which makes DNA double-strand breaks (DSBs) essential for meiotic recombination, has long been recalcitrant to biochemical study. …”
Publicado 2021
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16“…Previous work showed that the hydrophobicity of LLI (residues 54–56) within CR1 is important for Spo7 function in the Nem1–Spo7/Pah1 phosphatase cascade. …”
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17“…We detected no homologous recombination in the viable spores of spo11∆ diploid. Point mutations were fewer in spo11∆ than in wild‐type. …”
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18“…Programmed cell death in bacteria is generally associated with two-component toxin-antitoxin systems. The SpoIISABC system, originally identified in Bacillus subtilis, consists of three components: a SpoIISA toxin and the SpoIISB and SpoIISC antitoxins. …”
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19“…Methods: Here we investigate the effects of loss of SPO13 on cohesion during meiosis I using a live-cell imaging approach. …”
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20por Saylor, Timothy C., Savage, Christina R., Krusenstjerna, Andrew C., Jusufovic, Nerina, Zückert, Wolfram R., Brissette, Catherine A., Motaleb, Md., Schlax, Paula J., Stevenson, Brian“…The Borrelia burgdorferi SpoVG protein has previously been found to be a DNA- and RNA-binding protein. …”
Publicado 2023
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