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321por Lopez, M. Verónica, Viale, Diego L., Cafferata, Eduardo G. A., Bravo, Alicia I., Carbone, Cecilia, Gould, David, Chernajovsky, Yuti, Podhajcer, Osvaldo L.“…Therefore, we developed SPARC promoter-based CRAds since the SPARC gene is expressed both in malignant cells and in tumor-associated stromal cells. …”
Publicado 2009
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322por Lachmair, Martin, Cress, Ulrike, Fissler, Tim, Kurek, Simone, Leininger, Jan, Nuerk, Hans-Christoph“…The results showed that SPARC is grounded, in general. However, for cello player SPARC is also situated and embodied. …”
Publicado 2017
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323por Nakazawa, Yuko, Nakazawa, Seshiru, Kurozumi, Sasagu, Ogino, Misato, Koibuchi, Yukio, Odawara, Hiroki, Oyama, Tetsunari, Horiguchi, Jun, Fujii, Takaaki, Shirabe, Ken“…It was hypothesized that SPARC expression can affect the response to albumin-bound taxanes, including nab-PTX since SPARC binds albumin with a high affinity. …”
Publicado 2020
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324por Zhou, Xiaobo, Zhang, Lan, Qierang, Caihang, Huang, Min, Yang, Xin, Li, Liangang, Jiang, Jun“…BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC) is always considered as a marker of poor prognosis. …”
Publicado 2021
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325por Leurs, Nicolas, Martinand-Mari, Camille, Marcellini, Sylvain, Debiais-Thibaud, Mélanie“…The molecular evolution of sparc-L and its coexpression with fam20°C in catshark ameloblasts provides a unifying genetic basis that suggests that all convergent scpp duplicates inherited similar features from their sparc-L precursor. …”
Publicado 2022
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326por Chang, Sheng, Liu, Gang, Zhao, Lewei, Zheng, Weili, Yan, Di, Chen, Peter, Li, Xiangpan, Yang, Kunyu, Deraniyagala, Rohan, Stevens, Craig, Grills, Inga, Chinnaiyan, Prakash, Li, Xiaoqiang, Ding, Xuanfeng“…Nine retrospective clinical cases and the blind survey showed good agreement with the in silico dosimetric model and decision tree. Additionally, SPArc significantly reduced the treatment delivery time compared to VMAT (SPArc 184.46 ± 59.51s vs. …”
Publicado 2022
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327por Garcia, Flora do Vale, da Cunha, Maira Jaqueline, Schuch, Clarissa Pedrini, Schifino, Giulia Palermo, Balbinot, Gustavo, Pagnussat, Aline Souza“…The 10 MWT was instrumented with an inertial measurement unit system (IMU), which afforded the extraction of trunk angular velocities (yaw, roll, and pitch) and subsequent SPARC calculation. RESULTS: Movement smoothness was not influenced by gait speed in the control group, indicating that SPARC may constitute an additional and independent metric in the gait assessment. …”
Publicado 2021
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328por Bayle, Nicolas, Lempereur, Mathieu, Hutin, Emilie, Motavasseli, Damien, Remy-Neris, Olivier, Gracies, Jean-Michel, Cornec, Gwenaël“…Results: LDLJ, NARJ and N0C found backward movements to be smoother, while SPARC found the opposite. Inter- and intra-subject coefficients of variation were lowest for SPARC. …”
Publicado 2023
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329“…Therefore, this piece of writing aims to provide evidence supporting the potential use of SPARC/SPARC as a molecular therapy for muscle atrophy in the context of immobilization especially for elderly patients.…”
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330por Saes, Mique, Mohamed Refai, Mohamed Irfan, van Kordelaar, Joost, Scheltinga, Bouke L., van Beijnum, Bert-Jan F., Bussmann, Johannes B. J., Buurke, Jaap H., Veltink, Peter H., Meskers, Carel G. M., van Wegen, Erwin E. H., Kwakkel, Gert“…The goal of this observational study was to investigate how SPARC values change over time, and whether SPARC is longitudinally associated with the recovery from motor impairments reflected by the Fugl-Meyer motor assessment of the upper extremity (FM-UE) in the first 6 months after stroke. …”
Publicado 2021
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331por Huang, Kexin, Zhang, Yun, Shi, Xiaorui, Yin, Zhiqin, Zhao, Weiling, Huang, Liyu, Wang, Fu, Zhou, Xiaobo“…NSCLC patients with high SPARC expression could benefit more compared to low-SPARC-expression patients with cisplatin treatment. …”
Publicado 2023
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332“…Diverse pathologies (inflammation, tissues injuries, cancer, etc.) and physiological conditions (obesity, physical activity, etc.) induce the expression/secretion of the matricellular protein, secrete protein acidic and rich in cysteine (SPARC). SPARC contributes to the creation of an environment that is suitable for tissue regeneration through a variety of roles, including metabolic homeostasis, inflammation reduction, extracellular matrix remodeling and collagen maturation. …”
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333Secreted Protein Acidic and Rich in Cysteine as a Molecular Physiological and Pathological Biomarker“…Secreted protein acidic and rich in cysteine (SPARC) is expressed in diverse tissues and plays roles in various biological functions and processes. …”
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334por Cao, Yong, Wang, Xiaoyan, Tang, Li, Li, Yan, Song, Xueqin, Liu, Xu, Li, Mingying, Chen, Feng, Wan, Haisu“…EN2 greatly increased the expression of SPARC in Eca109. Site-directed mutagenesis revealed that the induction of SPARC was closely correlated with the protumor function of EN2. …”
Publicado 2020
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335por Jang, Seon Ho, Lee, Seunghwan, Millecamps, Magali, Danco, Alexander, Kang, HyungMo, Grégoire, Stéphanie, Suzuki‐Narita, Miyako, Stone, Laura S.“…Deletion of the SPARC gene results in progressive IDD beginning at 2 to 4 months of age. …”
Publicado 2021
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336por Zhao, Xiaojuan, Gabriëls, Ruben Y., Hooghiemstra, Wouter T. R., Koller, Marjory, Meersma, Gert Jan, Buist-Homan, Manon, Visser, Lydia, Robinson, Dominic J., Tenditnaya, Anna, Gorpas, Dimitris, Ntziachristos, Vasilis, Karrenbeld, Arend, Kats-Ugurlu, Gursah, Fehrmann, Rudolf S. N., Nagengast, Wouter B.“…This study identified SPARC, SULF1, PKCι, and DDR1 as promising targets for FME to differentiate DBE from NDBE tissue, for which SULF1-800CW and SPARC-800CW were successfully ex vivo evaluated. …”
Publicado 2022
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337por Duan, Jianchun, Hao, Yueqin, Wan, Rui, Yu, Sifan, Bai, Hua, An, Tongtong, Zhao, Jun, Wang, Zhijie, Zhuo, Minglei, Wang, Jie“…The main grade 3–4 toxicities experienced were neutropenia (9.4%) and leukopenia (7.8%). Patients with SPARC expression in tumor stroma but not in cancer cells had poorer progression‐free survival compared with those with negative SPARC expression in tumor stroma cells (3.3 vs. 5.0 months, P = 0.036). …”
Publicado 2017
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338Publicado 2005“…<br/><br/><b>LIBER, CERN, SPARC and SPARC Europe, OSI, and the OAi announce the 4th OAi workshop.…”
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339por Ito, Ko, Tomoki, Risa, Ogura, Naomi, Takahashi, Kosuke, Eda, Takashi, Yamazaki, Fumie, Kato, Yugo, Goss, Alastair, Kondoh, Toshirou“…When miR-204 was transfected into hDFC, the activity of ALP and protein levels of SPARC and Runx2 were decreased. mRNA levels of ALP, SPARC and Runx2 were also decreased by miR-204 transfection. …”
Publicado 2020
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340“…In this paper, we systematically evaluate the use of these measures on the kinematics measured by IMUs. We show that: (a) SPARC and LDLJ-V are valid measures of smoothness only when used with velocity; (b) SPARC and LDLJ-V applied on translational velocity reconstructed from IMU is highly error prone due to drift caused by integration of reconstruction errors; (c) SPARC can be applied directly on rotational velocities measured by a gyroscope, but LDLJ-V can be error prone. …”
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