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Mostrando 21 - 40 Resultados de 956 Para Buscar '"SPARC"', tiempo de consulta: 0.15s Limitar resultados
  1. 21
    “…Secreted protein acidic and rich in cysteine (SPARC), also termed osteonectin or BM-40, is a matricellular protein which regulates cell adhesion, extracellular matrix production, growth factor activity, and cell cycle. …”
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    SPARC: a potential target for functional nanomaterials and drugs
  2. 22
    “…Alterations in SPARC expression have been observed in a variety of solid tumours. …”
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    Differential SPARC mRNA expression in Barrett's oesophagus
  3. 23
    “…INTRODUCTION: SPARC is a matricellular protein, which, along with other extracellular matrix components including collagens, is commonly over-expressed in fibrotic diseases. …”
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    Attenuation of fibrosis in vitro and in vivo with SPARC siRNA
  4. 24
    “…In humans, SPARC protein expression is decreased as a function of age and disc degeneration. …”
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    DNA methylation of SPARC and chronic low back pain
  5. 25
    “…We aimed to investigate the expression of SPARC (secreted protein, acidic and rich in cysteine) in gastric cancer and its relationship with tumor angiogenesis and cancer cells proliferation. …”
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    The Role of SPARC Protein Expression in the Progress of Gastric Cancer
  6. 26
    por Cheng, Lamei, Sage, E. Helene, Yan, Qi
    Publicado 2013
    “…We have produced mouse SPARC with a FLAG-tag at the N-terminus of SPARC (Flag-SPARC, FSP) in a Bac-to-Bac baculoviral expression system. …”
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    SPARC Fusion Protein Induces Cellular Adhesive Signaling
  7. 27
    “…We then examined the relation of SPARC with glucose stimulated insulin secretion (GSIS) in primary human islets and the effect of SPARC overexpression on GSIS in beta cell lines. …”
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    A Role for SPARC in the Moderation of Human Insulin Secretion
  8. 28
    “…SPARC expression of postoperative specimens with and without preoperative chemotherapy was assessed to analyze the influence of chemotherapy on SPARC expression. …”
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    Change of SPARC expression after chemotherapy in gastric cancer
  9. 29
    “…Pten knockout additionally upregulated Sparc transcription in fibroblasts and promoted collagen shuttling out of the cell. …”
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    Pten regulates collagen fibrillogenesis by fibroblasts through SPARC
  10. 30
    “…We developed Sparse Predictive Activity through Recombinase Competition (SPARC), a generalizable toolkit that can express any effector in precise proportions of post-mitotic cells in Drosophila. …”
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    SPARC enables genetic manipulation of precise proportions of cells.
  11. 31
    “…Transcriptome analysis in the absence of SET27 revealed upregulated mRNA expression in the vicinity of SPARC peaks within the main body of chromosomes in addition to derepression of genes encoding variant surface glycoproteins (VSGs) located in subtelomeric regions. …”
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    The SPARC complex defines RNAPII promoters in Trypanosoma brucei
  12. 32
    “…SPARC-funded researchers are generating rich datasets from neuromodulation research that are curated and shared according to FAIR (Findable, Accessible, Interoperable, and Reusable) guidelines and are accessible to the public on the SPARC data portal. …”
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    SPARClink: an interactive tool to visualize the impact of the SPARC program
  13. 33
    Publicado 1994
    “…SPARC is a transiently expressed extracellular matrix-binding protein that alters cell shape and regulates endothelial cell proliferation in vitro. …”
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    SPARC is a source of copper-binding peptides that stimulate angiogenesis
  14. 34
    “…PURPOSE: SPARC (secreted protein, acidic, and rich in cysteine) is involved in extracellular matrix (ECM) organization. …”
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    Increased SPARC expression in primary angle closure glaucoma iris
  15. 35
    “…Thrombospondin-2 (TSP2) and osteonectin/BM-40/SPARC are matricellular proteins that are highly expressed by bone cells. …”
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    Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling
  16. 36
    “…Our laboratory has previously shown that full-length Secreted Protein Acidic and Rich in Cysteine (SPARC) and a SPARC peptide corresponding to the follistatin domain of the protein (FS-E) potently block angiogenesis and inhibit the growth of neuroblastoma tumors in preclinical models. …”
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    Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors
  17. 37
    por Shubham, Kumar, Mishra, Rajnikant
    Publicado 2012
    “…RESULTS: It was interesting to observe the co-localization and physical interaction of Pax6, transforming growth factor-beta (TGF-β), and secreted protein acidic and rich in cysteine (SPARC) in murine eyes. CONCLUSIONS: The interaction of Pax6, TGF-β, and SPARC in murine eyes indicates that Pax6 function is regulated through TGF-β, and SPARC influences the shuttling of Pax6 via the TGF-β/Smad signaling pathway.…”
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    Pax6 interacts with SPARC and TGF-β in murine eyes
  18. 38
    “…Secreted protein acidic and rich in cysteine (SPARC), a collagen-binding matricellular protein, has been implicated in procollagen processing and deposition. …”
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    Age and SPARC Change the Extracellular Matrix Composition of the Left Ventricle
  19. 39
    “…METHODS: Seventy-eight MF-CCA patients who underwent hepatectomy with curative intent were enrolled for an immunohistochemical study of SPARC. The expression of immunostaining of SPARC was characterized for both tumor and stromal tissues. …”
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    Peritumoral SPARC expression and patient outcome with resectable intrahepatic cholangiocarcinoma
  20. 40
    “…Suppression of SPARC expression was associated with increased Rac1-GTP levels and its membrane localization. …”
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    SPARC Controls Melanoma Cell Plasticity through Rac1
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