-
621“…RESULTS: A three-gene (GLT8D2, SPARC and VCAN) prognostic CAF model was established, and patients were markedly divided according to the riskscore of CAF model. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
622por Heezen, L.G.M., Abdelaal, T., van Putten, M., Aartsma-Rus, A., Mahfouz, A., Spitali, P.“…We show increased expression of specific genes in areas of muscle regeneration (Myl4, Sparc, Hspg2), fibrosis (Vim, Fn1, Thbs4) and calcification (Bgn, Ctsk, Spp1). …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
623“…In VNN‐gene‐enriched cells, Sparc, encoding the extracellular matrix (ECM) protein osteonectin, was robustly expressed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
624por Chiellini, Chiara, Cochet, Olivia, Negroni, Luc, Samson, Michel, Poggi, Marjorie, Ailhaud, Gérard, Alessi, Marie-Christine, Dani, Christian, Amri, Ez-Zoubir“…Quantitative analysis has been performed for 8 candidates: PAI-1, PEDF, BIGH3, PTX3, SPARC, ENO1, GRP78 and MMP2. Among them, PAI-1 was detected at day 0 and day 3 of osteoblast differentiation but never in adipocyte secretome. …”
Publicado 2008
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
625por van Wieringen, Tijs, Kalamajski, Sebastian, Lidén, Åsa, Bihan, Dominique, Guss, Bengt, Heinegård, Dick, Farndale, Richard W., Rubin, Kristofer“…Peptide II-44 corresponds to a region of collagen known to bind collagenases, discoidin domain receptor 2, SPARC (osteonectin), and fibronectin. In addition to binding fibronectin, peptide II-44 but not II-1 inhibited α(V)β(3)-mediated collagen gel contraction and, when immobilized on plastic, supported adhesion of cells. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
626por Imabuchi, Ryusei, Ohmiya, Yoshihiro, Joon Kwon, Hyuck, Onodera, Shin, Kitamura, Nobuto, Kurokawa, Takayuki, Ping Gong, Jian, Yasuda, Kazunori“…The expression degree of COL2A1, COL1A2, COL10A1, DCN, FMOD, SPARC, FLOD2, CHAD, CTGF, and COMP genes was greater in the regenerated tissue than in the normal cartilage. …”
Publicado 2011
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
627“…With data from several ESA field campaigns over agricultural sites (SPARC, AgriSAR, CEFLES2) we have evaluated the efficacy of two empirical methods that specifically make use of the new Sentinel-2 bands. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
628por Castellana, Bàrbara, Escuin, Daniel, Peiró, Gloria, Garcia-Valdecasas, Bárbara, Vázquez, Tania, Pons, Cristina, Pérez-Olabarria, Maitane, Barnadas, Agustí, Lerma, Enrique“…The genes upregulated in IDC samples, and probably associated with invasion, were related to the epithelial-mesenchymal transition (ASPN, THBS2, FN1, SPARC, and COL11A1), cellular adhesion (GJB2), cell motility and progression (PLAUR, PLAU, BGN, ADAMTS16, and ENPP2), extracellular matrix degradation (MMP11, MMP13, and MMP14), and growth/proliferation (ST6GAL2). qRT-PCR confirmed the expression patterns of ASPN, GJB2, ENPP2, ST6GAL2, and TMBS10. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
629“…Comparing our results with previous studies, we identified some genes known related to OP risk (e.g., ‘THSD4’, ‘CRHR1’, ‘HSD11B1’, ‘THSD7A’, ‘BMPR1B’ ‘ADCY10’, ‘PRL’, ‘CA8’,’ESRRA’, ‘CALM1’, ‘CALM1’, ‘SPARC’, and ‘LRP1’). Moreover, we uncovered novel osteoporosis susceptible genes (‘DICER1’, ‘PTMA’, etc.) that were not found previously but play functionally important roles in osteoporosis etiology from existing studies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
630por Keller, Kate E., Sun, Ying Ying, Vranka, Janice A., Hayashi, Lauren, Acott, Ted S.“…CD44, tenascin C and fibrillin-1 mRNA levels were reduced by 4MU treatment, but SPARC and CSPG6 mRNA levels were unaffected. Immunostaining of trabecular meshwork tissue after exposure to 4MU showed an altered localization pattern of HA-binding protein, versican and fibronectin. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
631por Dumaual, Carmen M., Steere, Boyd A., Walls, Chad D., Wang, Mu, Zhang, Zhong-Yin, Randall, Stephen K.“…Most notable among these were Filamin A, RhoGDIα, SPARC, hnRNPH2, and PRDX2. CONCLUSIONS AND SIGNIFICANCE: This systems-level approach sheds new light on the molecular networks underlying PRL-1 action and presents several novel directions for future, hypothesis-based studies.…”
Publicado 2013
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
632“…We found that overexpression of CSCs-related markers (ALDH1, Nanog and ABCG2) and up-regulation of EMT markers (Fibronectin, MMP-2, Periostin, SPARC, Snail and Slug), together with E- to N-cadherin switching, occurred preferentially in tumors containing a large proportion of spindle-shaped malignant cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
633por Relógio, Angela, Thomas, Philippe, Medina-Pérez, Paula, Reischl, Silke, Bervoets, Sander, Gloc, Ewa, Riemer, Pamela, Mang-Fatehi, Shila, Maier, Bert, Schäfer, Reinhold, Leser, Ulf, Herzel, Hanspeter, Kramer, Achim, Sers, Christine“…Among those genes are IFNGR2, PITX2, RFWD2, PPARγ, LOXL2, Rab6 and SPARC, all involved in cancer-related pathways. Using a bioinformatics approach, we extended the core-clock network and present its interconnection to the discriminative set of genes. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
634por Morales-Hernandez, Diana G., Genetos, Damian C., Working, David M., Murphy, Kaitlin C., Leach, J. Kent“…Compared to cells on PLG controls, RUNX2 expression in NHOsts on composite scaffolds was lower at both 7 and 21 days, while expression of genes encoding for bone matrix proteins (COL1A1 and SPARC) was higher on BG-PLG scaffolds at both time points. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
635por Bang, Sookhee, Jang, Sung Ill, Lee, Su Yeon, Baek, Yi-Yong, Yun, Jieun, Oh, Soo Jin, Lee, Chang Woo, Jo, Eun Ae, Na, Kun, Yang, Sugeun, Lee, Don Haeng, Lee, Dong Ki“…Moreover, implantation of the PEM inhibited tumor-stromal interaction-related expression of proteins such as CD44, SPARC, matrix metalloproteinase-2, and vimentin. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
636por Wan, Jinliang, Wen, Duo, Dong, Lili, Tang, Jun, Liu, Dongli, Liu, Yang, Tao, Zhonghua, Gao, Dongmei, Sun, Huichuan, Cao, Ya, Fan, Jia, Wu, Weizhong“…RESULTS: Six monoclonal cell lines with different organ site-specific tropism were established successfully. SPARC, VCAM1 and ANGPTL4 were found positively correlated with the potentials of lung metastasis, while ITGA1 had a positive relation to lymph node metastasis of enterocoelia. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
637por Szczyrba, Jaroslaw, Jung, Volker, Beitzinger, Michaela, Nolte, Elke, Wach, Sven, Hart, Martin, Sapich, Sandra, Wiesehöfer, Marc, Taubert, Helge, Wennemuth, Gunther, Eichner, Norbert, Stempfl, Thomas, Wullich, Bernd, Meister, Gunter, Grässer, Friedrich A.“…We demonstrate that the mRNAs of the death effector domain-containing protein (DEDD), the tumor necrosis factor receptor superfamily, member 10b protein (TNFRSF10B), the tumor protein p53 inducible nuclear protein 1 (TP53INP1), and the secreted protein, acidic, cysteine-rich (SPARC; osteonectin) are regulated by miRNAs miR-148a, miR-20a, miR-24, and miR-29a/b, respectively. …”
Publicado 2017
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
638por Koncar, Robert F., Feldman, Rebecca, Bahassi, El Mustapha, Hashemi Sadraei, Nooshin“…The only significant differences between cohorts were frequency of ERCC1 and SPARC loss as determined by IHC. In all four cancer types, oncogene mutation and PD‐L1 expression was relatively infrequent. …”
Publicado 2017
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
639por Kaochar, Salma, Dong, Jianrong, Torres, Marie, Rajapakshe, Kimal, Nikolos, Fotis, Davis, Christel M., Ehli, Erik A., Coarfa, Cristian, Mitsiades, Nicholas, Poulaki, Vasiliki“…Strikingly, ICG-001 suppressed the expression of genes associated with UM aggressiveness, including CDH1, CITED1, EMP1, EMP3, SDCBP, and SPARC. Notably, the transcriptomic footprint of ICG-001, when applied to a UM patient dataset, was associated with better clinical outcome. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
640“…The secretome derived from these three populations could promote the wound healing of corneal fibroblasts and reduce the expression of fibrotic markers SPARC and fibronectin. CONCLUSIONS: CSSCs maintained their stemness and multipotency after long-term storage, and secretome derived from these cells can be of paramount importance for corneal regeneration and prevention of fibrosis.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto