-
641por Umeda, Shinichi, Kanda, Mitsuro, Miwa, Takashi, Tanaka, Haruyoshi, Tanaka, Chie, Kobayashi, Daisuke, Suenaga, Masaya, Hattori, Norifumi, Hayashi, Masamichi, Yamada, Suguru, Nakayama, Goro, Fujiwara, Michitaka, Kodera, Yasuhiro“…PCR array analysis revealed that SUSD2 mRNA levels positively correlated with those of FZD7, CDH2, TGFB1, SPARC, ITGA5, and ZEB1. Functional analysis revealed that knockdown of SUSD2 significantly reduced the proliferation, migration, and invasiveness GC cell lines. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
642por Wang, Jun, Gao, Peng, Song, Yongxi, Sun, Jingxu, Chen, Xiaowan, Yu, Hong, Wang, Yu, Wang, Zhenning“…Based on these results, we built a prognostic signature with seven genes (FBN1,MMP1,PLAU,SPARC,COL1A2,COL2A1 and ATP4A) using stepwise multivariate Cox proportional hazard regression. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
643por Ariganello, Marianne B, Guadarrama Bello, Dainelys, Rodriguez-Contreras, Alejandra, Sadeghi, Shayan, Isola, Gaetano, Variola, Fabio, Nanci, Antonio“…Osteopontin expression and that of the proinflammatory SPARC protein and its stabilin 1 receptor were analyzed. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
644“…Furthermore, MMP activity, thrombospondin-1 and SPARC protein levels were significantly reduced in the media of CK-666-treated and shMyo10-silenced TM cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
645por Hall, Bradley R., Cannon, Andrew, Thompson, Christopher, Santhamma, Bindu, Chavez-Riveros, Alejandra, Bhatia, Rakesh, Nair, Hareesh B., Nickisch, Klaus, Batra, Surinder K., Kumar, Sushil“…Analysis by qRT-PCR demonstrated a significant downregulation of markers of activated stroma, POSTN, FN1, MMP9, and SPARC (p<0.0001), when treated with gemcitabine in combination with EC359. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
646por Jespersen, Naja Z., Feizi, Amir, Andersen, Eline S., Heywood, Sarah, Hattel, Helle B., Daugaard, Søren, Peijs, Lone, Bagi, Per, Feldt-Rasmussen, Bo, Schultz, Heidi S., Hansen, Ninna S., Krogh-Madsen, Rikke, Pedersen, Bente K., Petrovic, Natasa, Nielsen, Søren, Scheele, Camilla“…Brown fat precursor cells, which differentiated into functional brown adipocytes were present in the entire perirenal fat depot, regardless of state. We identified SPARC as a candidate adipokine contributing to a dormant BAT state, and CLSTN3 as a novel marker for multilocular BAT. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
647por Padial-Molina, Miguel, de Buitrago, Juan G., Sainz-Urruela, Raquel, Abril-Garcia, Dario, Anderson, Per, O’Valle, Francisco, Galindo-Moreno, Pablo“…Under osteogenic differentiation conditions, all MSC populations formed calcium deposits and expressed higher SPARC. Over time, the expression of MSI1 followed different patterns for the different MSC populations. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
648“…Osteogenic markers Coll1, osteonectin (Sparc), and osteocalcin as well as neural marker c-Fos and chondrogenic marker Coll2 were significantly reduced in P100 compared to P3 and P50. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
649por Zhang, Hui, Zhong, Jianing, Tu, Youbing, Liu, Benquan, Chen, Zhibo, Luo, Yunchen, Tang, Yaping, Xiao, Fei, Zhong, Jincai“…Among these, the high expression levels of five genes—SPP1, SPARC, BGN, POSTN, and COL1A2—were associated with poor disease-free survival of ESCC patients, as indicated by survival analysis. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
650por Minardi, S., Taraballi, F., Cabrera, F.J., Van Eps, J., Wang, X., Gazze, S.A., Fernandez-Mourev, Joseph S., Tampieri, A., Francis, L., Weiner, B.K., Tasciotti, E.“…Bone histomorphometry at 6 weeks revealed a significant amount of de novo bone matrix formation. qPCR demonstrated MHA/Coll scaffold full cellularization in vivo and the expression of both osteogenesis-associated genes (Spp1, Sparc, Col1a1, Runx2, Dlx5) as well as hematopoietic (Vcam1, Cd38, Sele, Kdr) and bone marrow stromal cell marker genes (Vim, Itgb1, Alcam). …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
651por Shoneye, Temitope, Orrego, Alessandra Tamashiro, Jarvis, Rachel, Men, Yuqin, Chiang, Ming Sum R., Yang, Yongjie“…However, the expression of astrocyte-derived Sparc, an important synaptogenic inhibitor, is consistently higher in hypothalamic astrocytes than in cortical astrocytes throughout postnatal development. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
652por Gao, Yuqian, Wang, Yi-Ting, Chen, Yongmei, Wang, Hui, Young, Denise, Shi, Tujin, Song, Yingjie, Schepmoes, Athena A., Kuo, Claire, Fillmore, Thomas L., Qian, Wei-Jun, Smith, Richard D., Srivastava, Sudhir, Kagan, Jacob, Dobi, Albert, Sesterhenn, Isabell A., Rosner, Inger L., Petrovics, Gyorgy, Rodland, Karin D., Srivastava, Shiv, Cullen, Jennifer, Liu, Tao“…A five-protein classifier which combined FOLH1, KLK3, TGFB1, SPARC, and CAMKK2 with existing clinical and pathological standard of care variables demonstrated significant improvement in predicting distant metastasis, achieving an area under the receiver-operating characteristic curve of 0.92 (0.86, 0.99, p = 0.001) and a negative predictive value of 92% in the training/testing analysis. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
653“…ABSTRACT: As an extracellular matrix protein, secreted protein acidic and rich in cysteine (SPARC)-like 1 (SPARCL1) is involved in various cell functions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
654“…The top 10 hub genes were CAM1, CDH1, CXCL12, JUN, CTGF, SERPINE1, CXCL1, EDN1, COL1A2, and SPARC. Analyzing the PPI network modules with close interaction, the 3 key modules in the whole PPI network were screened out. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
655por Zhang, Junfeng, Sun, Hui, Liu, Songsong, Huang, Wenjie, Gu, Jianyou, Zhao, Zhiping, Qin, Huan, Luo, Liwen, Yang, Jiali, Fang, Yongfei, Ge, Jiayun, Ni, Bing, Wang, Huaizhi“…KRT6A was found to be a DEG between PDAC and ANT that overlapped with DEGs between the M0-high group and the M0-low group in TCGA datasets, and it might alter and regulate TAMs via a collection of genes including COL5A2, COL1A2, MIR3606, SPARC, and COL6A3. TAMs, which could be a target of immunotherapy, might be influenced by genes through KRT6A and indicate an undesirable prognosis in PDAC.…”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
656por Keatinge, Marcus, Tsarouchas, Themistoklis M., Munir, Tahimina, Porter, Nicola J., Larraz, Juan, Gianni, Davide, Tsai, Hui-Hsin, Becker, Catherina G., Lyons, David A., Becker, Thomas“…Four of these mutants (tgfb1a, tgfb3, tnfa, sparc) retained the acute haCR phenotype, validating the approach. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
657por Wang, Junjun, Hu, Wei, Shen, Zhenyang, Liu, Teng, Dai, Weiming, Shen, Bo, Li, Xiaoman, Wu, Jingni, Lu, Lungen, Li, Shengli, Cai, Xiaobo“…Transcriptional trajectory analysis revealed different expression patterns of cells between CDE and DDC models and identified potential liver injury markers, such as Ets1, Gda, Itgam, and Sparc. Differential analysis identified 25 and 152 differentially expressed genes in CDE and DDC macrophages, respectively. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
658por Peng, Yajie, Zhu, Hui, Han, Bing, Xu, Yue, Liu, Xuemeng, Song, Huaidong, Qiao, Jie“…We finally filtered out CCR1, PPBP, PF4, CLU, KMT2D, GP6, and SPARC by the key gene clusters of the PPI network and manual screening of tissue-specific gene expression. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
659“…For example, the predicted expression patterns of SPARC, an invasion marker, highlighted a small tumor-invasion region difficult to identify using raw spatial transcriptome data alone because of a lack of measurements. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
660por Mehra, Reena, Tjurmina, Olga A., Ajijola, Olujimi A., Arora, Rishi, Bolser, Donald C., Chapleau, Mark W., Chen, Peng-Sheng, Clancy, Colleen E., Delisle, Brian P., Gold, Michael R., Goldberger, Jeffrey J., Goldstein, David S., Habecker, Beth A., Handoko, M. Louis, Harvey, Robert, Hummel, James P., Hund, Thomas, Meyer, Christian, Redline, Susan, Ripplinger, Crystal M., Simon, Marc A., Somers, Virend K., Stavrakis, Stavros, Taylor-Clark, Thomas, Undem, Bradley Joel, Verrier, Richard L., Zucker, Irving H., Sopko, George, Shivkumar, Kalyanam“…Opportunities to leverage the Common Fund’s SPARC (Stimulating Peripheral Activity to Relieve Conditions) program were characterized as related to nonpharmacologic neuromodulation and device-based therapies. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto