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Mostrando 661 - 680 Resultados de 956 Para Buscar '"SPARC"', tiempo de consulta: 0.19s Limitar resultados
  1. 661
    “…Among the hub proteins screened in the PPI network, APOA1, APOB, F2, and SPARC may be targeted by many herbal medicines and considered as key proteins. …”
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    Proteomics Reveals Molecular Changes in Insomnia Patients with More Dreams
  2. 662
    “…As representations, the feature genes Cldn7, Gjb6, Sparc, Cldn3, Cited1, Krt17, Spp1, Cldn4, Gjb2 and Cldn19 might play an important role in classifying the epithelial mammary cells. …”
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    Identifying luminal and basal mammary cell specific genes and their expression patterns during pregnancy
  3. 663
    “…Differential gene expression analysis revealed 3194 upregulated genes in PVR compared with ILM, including FN1 and SPARC, which contribute to biological processes, such as extracellular matrix (ECM) organization. …”
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    Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy
  4. 664
    “…These indicators were correlation coefficients (CC) and root mean square deviations (RMSD) comparing gait cycle kinematics measured before and after the training session and also movement smoothness estimates (SPARC, LDLJ). Heart rate and lactatemia measures did not attest to a significant physiological fatigue. …”
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    Detection of Horse Locomotion Modifications Due to Training with Inertial Measurement Units: A Proof-of-Concept
  5. 665
    “…Gene expression of MMP1 as well as SPARC is reduced in chondrocytes due to treatment with GSN in the OA model. …”
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    Recombinant human gelsolin promotes the migration of human articular cartilage chondrocytes by regulating gene expression in vitro
  6. 666
    “…High endothelial venule protein/SPARC-like 1 (hevin/Sparcl1) is an astrocyte-secreted protein that regulates synapse formation in the brain. …”
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    Hevin/Sparcl1 drives pathological pain through spinal cord astrocyte and NMDA receptor signaling
  7. 667
    “…Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan 1 (SPOCK1) has been reported to play an oncogenic role in certain cancer types; however, the role of SPOCK1 in the progression of clear cell renal cell carcinoma (ccRCC) remains elusive. …”
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    Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition
  8. 668
    “…MSCs not only differentiated toward osteoblast lineage cells but also expressed higher levels of osteogenic-related markers, including Sparc and Col1a1. This was confirmed by lineage tracing in transgenic mouse models and human samples from oral inflammatory-related alveolar bone lesions. …”
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    Creating an atlas of the bone microenvironment during oral inflammatory-related bone disease using single-cell profiling
  9. 669
    “…We validate that expression of SPARC, a marker of adaptive regeneration, is also induced in corneal epithelial wound healing and accelerates wound closure in a corneal epithelial cell scratch assay. …”
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    Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis
  10. 670
    “…BACKGROUND: In the phase III SPARC trial, satraplatin, an oral platinum analogue, demonstrated anticancer activity in men with metastatic castration-resistant prostate cancer (mCRPC). …”
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    Biomarker Development Trial of Satraplatin in Patients with Metastatic Castration-Resistant Prostate Cancer
  11. 671
    “…HSA(rQTY) nanoparticles exhibited efficient cellular internalization through the cell membrane albumin binding protein GP60, or SPARC (secreted protein, acidic and rich in cysteine)-mediated pathways. …”
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    Reverse-QTY code design of active human serum albumin self-assembled amphiphilic nanoparticles for effective anti-tumor drug doxorubicin release in mice
  12. 672
    “…METHODS: We conducted a prospective cohort study nested within the Crohn’s & Colitis Foundation’s IBD Partners and SPARC IBD initiatives. We identified anti-TNF experienced patients with UC initiating vedolizumab or tofacitinib and analyzed PROs reported approximately 6 months later (minimum 4 months, maximum 10 months). …”
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    Comparing Patient-Reported Outcomes Among Anti-TNF Experienced Patients With Ulcerative Colitis Initiating Vedolizumab Versus Tofacitinib
  13. 673
    “…Over-expression of ECM glycoprotein, Secreted Protein Acidic and Cysteine Rich (SPARC) in the IPF HLF matrix restricts KRT5(+) cell migration in vitro. …”
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    Lung extracellular matrix modulates KRT5(+) basal cell activity in pulmonary fibrosis
  14. 674
    “…Of interest were 10 genes (VEGFA, DCN, SPARC, COL6A2, MGP, CYR61, ANXA6, LGALS1, C1QA and C1QB) directly connected to fibronectin 1 (FN1). …”
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    A bronchial gene signature specific for severe COPD that is retained in the nose
  15. 675
    “…Through the description of testable candidates and the experimental validation of a number of UTR-SNPs discovered on the secreted protein acidic and rich in cysteine (SPARC) gene, this report illustrates the utility of a cross-talk between in silico transcriptomics and cancer genetics.…”
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    In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions
  16. 676
    “…We focused on an inferred core network with CDKN1A (p21(WAF1/CIP1)) as the hub, and extracted seven candidates for gastric carcinogenesis (MMP7, SPARC, SOD2, INHBA, IGFBP7, NEK6, LUM). They were classified into two groups based on the correlation between expression level and stage. …”
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    Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis
  17. 677
    por Chittka, A, Volff, JN, Wizenmann, A
    Publicado 2009
    “…Our phylogenetic analysis of QR1 shows that it is the chick orthologue of Sparc-like 1/Hevin/Mast9 gene in mice, rats, dogs and humans, a protein involved in cell adhesion. …”
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    Identification of genes differentially expressed in dorsal and ventral chick midbrain during early Development
  18. 678
    “…BACKGROUND: Analysis of 23 published transcriptome studies allowed us to identify nine genes displaying frequent alterations in HNSCC (FN1, MMP1, PLAU, SPARC, IL1RN, KRT4, KRT13, MAL, and TGM3). We aimed to independently confirm these dysregulations and to identify potential relationships with clinical data for diagnostic, staging and prognostic purposes either at the tissue level or in saliva rinse. …”
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    Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse
  19. 679
    “…RESULTS: In the NS subtype, 152 genes showed a significantly higher expression, including genes involved in extracellular matrix (ECM) remodelling and ECM deposition similar to wound healing. Among these were SPARC, CTSK and COLI. Immunohistochemistry revealed that the NS-related genes were mainly expressed by macrophages and fibroblasts. …”
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    Inflammation and tissue repair markers distinguish the nodular sclerosis and mixed cellularity subtypes of classical Hodgkin's lymphoma
  20. 680
    “…Interestingly, the platelet-secreted glycoprotein SPARC was down-regulated in NSTE-ACS patients compared to stable controls, which is consistent with a secretion process from activated platelets. …”
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    Proteins Involved in Platelet Signaling Are Differentially Regulated in Acute Coronary Syndrome: A Proteomic Study
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