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81“…OBJECTIVE: SPARC is a key determinant of invasion and metastasis in some tumors, such as gliomas, melanomas and prostate tumors. …”
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82por Mohamad Al-Ali, Badereddin, Shamloul, Rany, Hutterer, Georg C., Puchwein, Erika, Pummer, Karl, Avian, Alexander, Primus, Günter“…To evaluate the impact of SPARC on female sexual function. Methods. 151 women with a mean age of 60 ± 11.90 and SUI had a complete urodynamic investigation and underwent SPARC operation. 98 women completed the validated female sexual function index questionnaire (FSFI) at baseline and 94 women at follow-up. …”
Publicado 2013
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83por Chen, Zi-Yi, Zhang, Jun-Ling, Yao, Hong-Xin, Wang, Peng-Yuan, Zhu, Jing, Wang, Wei, Wang, Xin, Wan, Yuan-Lian, Chen, Shan-Wen, Chen, Guo-Wei, Liu, Yu-Cun“…Secreted protein acidic and rich in cysteine (SPARC) gene has been shown to be epigenetically silenced in several cancers. …”
Publicado 2014
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84“…Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein that regulates several cellular events, including inflammation and tissue remodelling. …”
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85por Popova, Antonia P., Cui, Tracy X., Kaciroti, Niko, Goldsmith, Adam M., Linn, Marisa J., Pryhuber, Gloria S., Hershenson, Marc B.“…SPARC deposition was increased in the lungs of patients with BPD. …”
Publicado 2015
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86“…We describe a versatile and efficient linear complexity consensus algorithm Sparc to facilitate de novo genome assembly. Sparc builds a sparse k-mer graph using a collection of sequences from a targeted genomic region. …”
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87“…Medulloblastoma is the most common malignant brain tumor in children. SPARC (secreted protein acidic and rich in cysteine), a multicellular non-structural glycoprotein is known to be involved in multiple processes in various cancers. …”
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88por Beck, Yoav, Herman, Talia, Brozgol, Marina, Giladi, Nir, Mirelman, Anat, Hausdorff, Jeffrey M.“…Smoothness of gait was estimated with SPARC (respectively from acceleration and angular velocity signals, SPARC-Acc and SPARC-Gyro) and harmonic ratios. …”
Publicado 2018
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89por Seet, Li Fong, Tan, Yang Fei, Toh, Li Zhen, Chu, Stephanie WL, Lee, Ying Shi, Venkatraman, Subbu S, Wong, Tina T“…Scrambled (siScram) or Sparc (siSparc) siRNAs, loaded on layer-by-layer (LbL) nanoparticles, were injected into the conjunctiva immediately after surgery. …”
Publicado 2018
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90por Ding, Weifeng, Pu, Weilin, Jiang, Shuai, Ma, Yanyun, Liu, Qingmei, Wu, Wenyu, Chu, Haiyan, Zou, Hejian, Jin, Li, Wang, Jiucun, Zhou, Xiaodong“…BACKGROUND: The genes of SPARC, CCR2, and SMAD3 are implicated in orchestrating inflammatory response that leads to fibrosis in scleroderma and other fibrotic disorders. …”
Publicado 2018
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91por Munk, Rachel, Martindale, Jennifer L., Yang, Xiaoling, Yang, Jen-Hao, Grammatikakis, Ioannis, Di Germanio, Clara, Mitchell, Sarah J., de Cabo, Rafael, Lehrmann, Elin, Zhang, Yongqing, Becker, Kevin G., Raz, Vered, Gorospe, Myriam, Abdelmohsen, Kotb, Panda, Amaresh C.“…Further investigation of the regulatory influence of miR-451a identified as one of the major targets Sparc mRNA, which encodes a secreted protein acidic and rich in cysteine (SPARC) that functions in wound healing and cellular differentiation. …”
Publicado 2019
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92por Wang, Qianjun, Yang, Qianqian, Zhang, Ali, Kang, Zhiqiang, Wang, Yingsheng, Zhang, Zhentao“…The mechanistic investigation on roles of SPARC in HO was examined through gain- and loss-of-function approaches of SPARC, with alkaline-phosphatase (ALP) activity, mineralized nodules, and osteocalcin (OCN) content measured. …”
Publicado 2019
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93por Zhang, Danyang, Xu, Jiawei, Yang, Peng, Wen, Yifan, He, Hua, Li, Jiaxiao, Liang, Juntong, Zheng, Yining, Zhang, Zijing, Wang, Xianwei, Yu, Xiang, Wang, Eryao, Lei, Chuzhao, Chen, Hong, Huang, Yongzhen“…SPARC is a cysteine-rich acidic secreted protein. …”
Publicado 2020
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94por Hu, Jianwen, Ma, Yongchen, Ma, Ju, Chen, Shanwen, Zhang, Xiaoqian, Guo, Shihao, Huang, Zhihao, Yue, Taohua, Yang, Yanpeng, Ning, Yingze, Zhu, Jing, Wang, Pengyuan, Wang, Xin, Chen, Guowei, Liu, Yucun“…This study shows that macrophages are an important source of the SPARC and that SPARC overexpression in M2 can reduce M2-mediated promoting proliferation, migration and anti-apoptotic effects in gastric cancer. …”
Publicado 2020
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95por Hartley, Christopher, Rowan, Daniel, Chen, Xiuxu, Gomez-Arellano, Luisa, West, Anna Marie, Oshima, Kiyoko, Mackinnon, Alexander Craig“…Secreted Protein Acid and Rich in Cysteine (SPARC) is an extracellular glycoprotein secreted by fibroblasts and osteoblasts in normal tissues. …”
Publicado 2020
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96por Fabrizio, Federico Pio, Sparaneo, Angelo, Fontana, Andrea, Mazza, Tommaso, Graziano, Paolo, Pantalone, Angela, Parente, Paola, Centra, Flavia, Orlando, Natalizia, Trombetta, Domenico, la Torre, Annamaria, Ferretti, Gian Maria, Taurchini, Marco, Di Micco, Concetta Martina, Maiello, Evaristo, Fazio, Vito Michele, Rossi, Antonio, Muscarella, Lucia Anna“…Anyhow, the data concerning the epigenetic mechanism of SPARC deregulation and its prognostic value in lung cancer are still incomplete. …”
Publicado 2020
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97por Cassarly, Christy, Doyle, Anna, Ly, Trinh, Horn, Janet, Aitchison, Mary, Elm, Jordan, Fridriksson, Julius, Bonilha, Leonardo“…METHODS: The Speech Entrainment for Aphasia Recovery (SpARc) trial is a prospective, randomized, assessor-blinded, multicenter phase II clinical trial studying persons with chronic post-stroke non-fluent aphasia. …”
Publicado 2021
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98“…However, the prognostic value of SPARC in patients with HCC remains unclear. Therefore, we performed a meta-analysis to evaluate the relationship between the expression of SPARC and the prognosis of patients with HCC. …”
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99por Wang, Weixia, Zhu, Tingheng, Wan, Pinjun, Wei, Qi, He, Jiachun, Lai, Fengxiang, Fu, Qiang“…In this study, the gene for SPARC was identified and functionally analysed from N.lugens. …”
Publicado 2022
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