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121“…Authors operationalize the SPARC model with a checklist to assist program stakeholders in designing for and assessing collaborative practice in support of project goals in funded academic partnership projects, emphasizing the contributions of collaborative practice in promoting diversification of the professoriate.…”
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122por Shi, Shuai, Ma, Hong-Yan, Han, Xin-Ying, Sang, Yin-Zhou, Yang, Ming-Yue, Zhang, Zhi-Gang“…Secreted protein, acidic and rich in cysteine (SPARC, also known as osteonectin), is a small molecule glycoprotein associated with cell secretions. …”
Publicado 2022
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123Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cellspor MacDonald, William W., Swaminathan, Swarup S., Heo, Jae Young, Castillejos, Alexandra, Hsueh, Jessica, Liu, Brian J., Jo, Diane, Du, Annie, Lee, Hyunpil, Kang, Min Hyung, Rhee, Douglas J.“…We investigated SPARC as a potential target for lowering IOP. We hypothesized that suppressing SPARC will decrease IOP, decrease structural JCT ECM proteins, and alter the levels of MMPs and/or their inhibitors. …”
Publicado 2022
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124por Enriquez, Claudia, Cancila, Valeria, Ferri, Renata, Sulsenti, Roberta, Fischetti, Irene, Milani, Matteo, Ostano, Paola, Gregnanin, Ilaria, Mello-Grand, Maurizia, Berrino, Enrico, Bregni, Marco, Renne, Giuseppe, Tripodo, Claudio, Colombo, Mario P., Jachetti, Elena“…Castration induced upregulation of GRP78 in tumor cells, which triggers miR29-b–mediated downregulation of the matricellular protein SPARC in the nearby stroma. SPARC downregulation enabled stromal cells to release IL6, a known inducer of NED. …”
Publicado 2021
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125por Li, Zhuo-Yao, Zhou, Ai-Fang, Li, Gan, Zhou, Long-Yun, Pu, Pei-Min, Zhu, Ke, Zheng, Zhong, Wang, Yong-Jun, Liang, Qian-Qian, Yao, Min, Cui, Xue-Jun“…In this study, we evaluated whether SPARC-null mice may serve as an animal model for CSCC. …”
Publicado 2022
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126por Ferrario, M., Alesini, D., Anania, M.P., Artioli, M., Bacci, A., Bartocci, S., Bedogni, R., Bellaveglia, M., Biagioni, A., Bisesto, F., Brandi, F., Brentegani, E., Broggi, F., Buonomo, B., Campana, P.L., Campogiani, G., Cannaos, C., Cantarella, S., Cardelli, F., Carpanese, M., Castellano, M., Castorina, G., Catalan Lasheras, N., Chiadroni, E., Cianchi, A., Cimino, R., Ciocci, F., Cirrincione, D., Cirrone, G.A.P., Clementi, R., Coreno, M., Corsini, R., Croia, M., Curcio, A., Costa, G., Curatolo, C., Cuttone, G., Dabagov, S., Dattoli, G., D'Auria, G., Debrot, I., Diomede, M., Drago, A., Di Giovenale, D., Di Mitri, S., Di Pirro, G., Esposito, A., Faiferri, M., Ficcadenti, L., Filippi, F., Frasciello, O., Gallo, A., Ghigo, A., Giannessi, L., Giribono, A., Gizzi, L., Grudiev, A., Guiducci, S., Koester, P., Incremona, S., Iungo, F., Labate, L., Latina, A., Licciardi, S., Lollo, V., Lupi, S., Manca, R., Marcelli, A., Marini, M., Marocchino, A., Marongiu, M., Martinelli, V., Masciovecchio, C., Mastino, C., Michelotti, A., Milardi, C., Minicozzi, V., Mira, F., Morante, S., Mostacci, A., Nguyen, F., Pagnutti, S., Pellegrino, L., Petralia, A., Petrillo, V., Piersanti, L., Pioli, S., Polese, D., Pompili, R., Pusceddu, F., Ricci, A., Ricci, R., Rochow, R., Romeo, S., Rosenzweig, J.B., Rossetti Conti, M., Rossi, A.R., Rotundo, U., Sabbatini, L., Sabia, E., Sans Plannell, O., Schulte, D., Scifo, J., Scuderi, V., Serafini, L., Spataro, B., Stecchi, A., Stella, A., Shpakov, V., Stellato, F., Turco, E., Vaccarezza, C., Vacchi, A., Vannozzi, A., Variola, A., Vescovi, S., Villa, F., Wuensch, W., Zigler, A., Zobov, M.“…On the wake of the results obtained so far at the SPARC_LAB test-facility at the Laboratori Nazionali di Frascati (Italy), we are currently investigating the possibility to design and build a new multi-disciplinary user-facility, equipped with a soft X-ray Free Electron Laser (FEL) driven by a ∼ 1 GeV high brightness linac based on plasma accelerator modules. …”
Publicado 2018
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127“…Secreted protein acidic and rich in cysteine (SPARC) is a member of the extracellular matrix glycoprotein family that binds to calcium ions. …”
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128por Dalla-Torre, Cristiane A, Yoshimoto, Maisa, Lee, Chung-Hae, Joshua, Anthony M, de Toledo, Silvia RC, Petrilli, Antônio S, Andrade, Joyce AD, Chilton-MacNeill, Susan, Zielenska, Maria, Squire, Jeremy A“…Higher levels of THBS3 maintain the capacity of angiogenesis. High levels of SPARC are not required for tumor progression but are necessary for tumor growth and maintenance. …”
Publicado 2006
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129Publicado 1987“…High levels of SPARC RNA are found in osteoblasts and odontoblasts. …”
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130por Rotta, Gianluca, Matteoli, Gianluca, Mazzini, Elisa, Nuciforo, Paolo, Colombo, Mario P., Rescigno, Maria“…We studied the function of the matricellular protein secreted protein, acidic and rich in cysteine (SPARC/osteonectin) in the dissemination of locally injected Salmonella typhimurium and in the subsequent immune response. …”
Publicado 2008
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131por Fuchshofer, Rudolf, Kottler, Ulrike B., Ohlmann, Anne V., Schlötzer-Schrehardt, Ursula, Jünemann, Anselm, Kruse, Friedrich E., Ohlmann, Andreas“…PURPOSE: To investigate the expression of the matricellular protein SPARC (secreted acidic cysteine-rich glycoprotein) in scarred human Tenon’s capsule and in cultured human Tenon’s fibroblasts (HTF), and to analyze the influence of SPARC on cell proliferation and collagen matrix contraction in vitro. …”
Publicado 2011
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132“…Recently, we reported that secreted protein acidic and rich in cysteine (SPARC)–deficient mice exhibited decreased pericyte-associated vessels in an orthotopic model of pancreatic cancer, suggesting that SPARC influences pericyte behavior. …”
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134por Wang, Hai-Yun, Li, Yang-Yang, Shao, Qiong, Hou, Jing-Hui, Wang, Fang, Cai, Man-Bo, Zeng, Yi-Xin, Shao, Jian-Yong“…The difference of SPARC expression in the cell lines was tested using a t-test method. …”
Publicado 2012
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135“…BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC), a calcium-binding matricellular glycoprotein, is implicated in the progressions of some cancers. …”
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137por Yunker, Christopher K, Golembieski, William, Lemke, Nancy, Schultz, Chad R, Cazacu, Simona, Brodie, Chaya, Rempel, Sandra A“…The data demonstrate that SPARC upregulates glioma matrix, collagen I is a constituent of the matrix and SPARC promotes collagen fibrillogenesis. …”
Publicado 2008
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138por Trombetta-eSilva, Jessica, Eadie, Erik P., Zhang, Yuhua, Norris, Russell A., Borg, Thomas K., Bradshaw, Amy D.“…Immunostaining of SPARC overlapped with that of collagen I but not to that of fibronectin in 3D cultures. …”
Publicado 2013
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139por Xu, Lu, Ping, Fan, Yin, Jinhua, Xiao, Xinhua, Xiang, Hongding, Ballantyne, Christie M., Wu, Huaizhu, Li, Ming“…OBJECTIVE: Recent studies suggested that secreted protein acidic and rich in cysteine (SPARC), a novel adipokine, is a key player in the pathology of obesity and type 2 diabetes. …”
Publicado 2013
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140“…BACKGROUND: Serum protein acidic and rich in cysteine (SPARC) is a matricellular secreted glycoprotein that performs several cellular functions and has been implicated in tumorigenesis in a variety of tumor types. …”
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