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81por Liu, Shujun, Zhu, Yadi, Zhang, Chenxi, Meng, Xiangrui, Sun, Bo, Zhang, Guojun, Fan, Yubo, Kang, Xixiong“…Background: Soluble PD-L1 (sPD-L1) in the circulation has been documented to activate global immunosuppression and is considered a predictor of negative clinical outcomes in several malignances. …”
Publicado 2020
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83“…In this method, local features extracted from convolutional neural network are used to construct the SPD matrix, and a deep learning algorithm for the SPD matrix is used to detect target signals. …”
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84“…In order to combine soluble programmed cell death protein 1 (sPD-1)-mediated immune checkpoint therapy and chlorin e6 (Ce6)-assisted SDT, nanobubbles (NBs) were generated to simultaneously load sPD-1 and Ce6. …”
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85por Cao, Kun, Zhang, Tianlong, Li, Nan, Yang, Xiao-Yan, Ding, Jianping, He, Qing-Yu, Sun, Xuesong“…SPD_0310 can interact with many hemin-binding proteins (SPD_0090, SPD_1609, and GAPDH) located on the cell surface, which contributes to hemin transfer to the cytoplasm. …”
Publicado 2022
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86por Beserra, Danielle Rosa, Alberca, Ricardo Wesley, Branco, Anna Claudia Calvielli Castelo, de Mendonça Oliveira, Luana, de Souza Andrade, Milena Mary, Gozzi-Silva, Sarah Cristina, Teixeira, Franciane Mouradian Emidio, Yendo, Tatiana Mina, da Silva Duarte, Alberto José, Sato, Maria Notomi“…Moreover, we observed an increase in sPD-L1 circulant levels associated with the severity of the disease. …”
Publicado 2022
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87“…ILC2 and M2 were confirmed to be related to immunosuppression in tumor patients. To determine whether sPD1 and sPDL1 are correlated with the ratio of ILC2 and M2 is helpful to explore the possibility of using sPD1 and sPDL1 as tumor molecular markers. …”
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88por Skryabina, Nataliya, Aptukov, Valery, Romanov, Petr, Fruchart, Daniel, de Rango, Patricia, Girard, Gregory, Grandini, Carlos, Sandim, Hugo, Huot, Jacques, Lang, Julien, Cantelli, Rosario, Leardini, FabriceEnlace del recurso
Publicado 2018
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89por Xu, Li, Jiang, Lichun, Nie, Liuyan, Zhang, Songzhao, Liu, Lei, Du, Yan, Xue, Jing“…Increased sPD-1 may be a valuable biomarker to predict the presence of ILD in patients with RA. …”
Publicado 2021
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90“…Three hundred patients with CRC were included in this study. sPD-L1 was measured by ELISA. Pretreatment levels of sPD-L1 were significantly elevated in CRC patient sera compared to healthy control (HC) (P<0.001). …”
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91por Zhang, Yang, Li, Zongjuan, Chen, Yixing, Yang, Ping, Hu, Yong, Zeng, Zhaochong, Du, Shisuo“…Furthermore, patients with higher rate of sPD-L1 increase after RT have better treatment response (p < 0.001), PFS (p = 0.032) and OS (p = 0.045). …”
Publicado 2022
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93“…This study explored the ultrasound-mediated co-delivery of miR-34a and sPD-1 complexes with microbubbles for synergistic cancer therapy. …”
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94“…The expression and role of sPD-L1 during pregnancy are also evoked. The structural heterogeneity of sPD-L1 proteins, and associated functional/cellular plurality, should be kept in mind when considering sPD-L1 as a biomarker or as a drug target. …”
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95“…Both subdural drain (SDD) and subperiosteal drain (SPD) have been reported to lower the recurrence rate when used in conjunction with burr holes. …”
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96“…BACKGROUND: Styrylpyrone derivative (SPD) is a plant-derived pharmacologically active compound extracted from Goniothalamus sp. …”
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97por Wueseke, Oliver, Zwicker, David, Schwager, Anne, Wong, Yao Liang, Oegema, Karen, Jülicher, Frank, Hyman, Anthony A., Woodruff, Jeffrey B.“…We found that a mutant version of SPD-5 that is insensitive to PLK-1 phosphorylation (SPD-5(4A)) could localize to PCM but was unable to rescue the reduction in PCM size and density when wild-type SPD-5 levels were decreased. …”
Publicado 2016
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98por Zhang, Bing, Guo, Fei, Ma, Yuqin, Song, Yingcai, Lin, Rong, Shen, Fu-Yi, Jin, Guo-Zhang, Li, Yang, Liu, Zhi-Qiang“…Our results showed that l-SPD exerted antidepressant-like effects on the Sprague-Dawley rat CMS model of depression. …”
Publicado 2017
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99por Katongole, Paul, Sande, Obondo J., Reynolds, Steven J., Joloba, Moses, Kajumbula, Henry, Kalungi, Samuel, Ssebambulidde, Kenneth, Nakimuli, Cynthia, Atuheirwe, Maxine, Orem, Jackson, Niyonzima, NixonEnlace del recurso
Publicado 2022
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100por Mansouri, Ladan, Sendic, Senka, Havervall, Sebastian, Thålin, Charlotte, Jacobson, Stefan H., Lundahl, Joachim“…In logistic regression models patients with high BAFF, sCD25 and sPD-L1 levels had significantly higher risk of both in-hospital and 30-day mortality while there was no association to eGFR. …”
Publicado 2022
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