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241por Beard, Niall, Bacall, Finn, Nenadic, Aleksandra, Thurston, Milo, Goble, Carole A, Sansone, Susanna-Assunta, Attwood, Teresa K“…To address this issue, we have developed a new platform—TeSS—which aggregates geographically distributed information and presents it in a central, feature-rich portal. …”
Publicado 2020
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242“…Evidence was gathered using comparative genomics and sequence analysis tools, and indicated that this islet was comprised of Type VI secretion system (T6SS) and contact-dependent growth inhibition (CDI) genes, the majority of which appeared to encode orphan immunity proteins that protected against the activities of effectors and toxins absent from the S. …”
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243por Szeto, Hazel, Zhang, Ying, Nakagawa, Yusuke, Carballo, Camila, Green, Samuel, Deng, Xianghua, Rodeo, Scott, Zhang, Xueying“…OBJECTIVES: The purpose of this study is to investigate the therapeutic potential of SS-31, a target to improve mitochondria function for the treatment of tendinopathy using human tenocytes. …”
Publicado 2020
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244“…Aptamers are short single-stranded DNA (ssDNA), RNA or synthetic XNA molecules, which are used as a class of affinity binders recognizing target molecules with a very high affinity and specificity. …”
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245“…Here, we review the role of cholesterol and other lipids in ssRNA+ infection.…”
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246por Wu, Weijian, Li, Shanshan, Yang, Min, Lin, Yongwen, Zheng, Kaibin, Akutse, Komivi Senyo“…Anopheles gambiae s.s. is a key vector of Plasmodium parasites. Repellents, which may be a promising alternative to pesticides used to control malaria mosquitoes. …”
Publicado 2020
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248por Mishima, Kazuhiko, Shirahata, Mitsuaki, Adachi, Junichi, Suzuki, Tomonari, Uchida, Eita, Nishikawa, RyoEnlace del recurso
Publicado 2020
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250por Bajunaid, Waad, Haidar-Ahmad, Nathaline, Kottarampatel, Anwer Hasil, Ourida Manigat, France, Silué, Navoun, F. Tchagang, Caetanie, Tomaro, Kyle, Campbell-Valois, François-Xavier“…They are Escherichia coli pathovars that are characterized by the harboring of a large plasmid that encodes most virulence genes, including a type III secretion system (T3SS). The archetypal element of the T3SS is the injectisome, a syringe-like nanomachine composed of approximately 20 proteins, spanning both bacterial membranes and the cell wall, and topped with a needle. …”
Publicado 2020
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251“…Some predatory species, such as Vibrio cholerae, use their T6SS in an untargeted fashion while in contrast, Pseudomonas aeruginosa assembles and fires its T6SS apparatus only after detecting initial attacks by other bacterial prey cells; this targeted attack strategy has been termed the T6SS tit-for-tat response. …”
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253por Zhang, Wenqing, Lin, Mingqun, Yan, Qi, Budachetri, Khemraj, Hou, Libo, Sahni, Ashweta, Liu, Hongyan, Han, Nien-Ching, Lakritz, Jeffrey, Pei, Dehua, Rikihisa, Yasuko“…Ehrlichia translocated factor-1 (Etf-1), a type IV secretion system (T4SS) effector, is a primary virulence factor for an obligatory intracellular bacterium, Ehrlichia chaffeensis. …”
Publicado 2021
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254por Kuang, Junqi, Zhai, Ziwei, Li, Pengli, Shi, Ruona, Guo, Wenjing, Yao, Yuxiang, Guo, Jing, Zhao, Guoqing, He, Jiangpin, Xu, Shuyang, Wu, Chuman, Yu, Shengyong, Zhou, Chunhua, Wu, Linlin, Qin, Yue, Cai, Baomei, Li, Wei, Wu, Zichao, Li, Xiaoxi, Chu, Shilong, Yang, Tingting, Wang, Bo, Cao, Shangtao, Li, Dongwei, Zhang, Xiaofei, Chen, Jiekai, Liu, Jing, Pei, Duanqing“…Mechanistically, SS18 forms microscopic condensates in nuclei through a C-terminal intrinsically disordered region (IDR) rich in tyrosine, which, once mutated, no longer form condensates nor rescue SS18(−/−) defect in PST. …”
Publicado 2021
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255“…Additionally, phagocytosis of HIV-infected CEM-SS T cells was increased approximately 4-fold. Expression of VISTA on infected CEM-SS T cells was detected in 16.7% of cells, which correlated with the increased phagocytosis observed. …”
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256por Chang, Ching-Mao, Wu, Po-Chang, Lin, Jr-Rung, Jan Wu, Yeong-Jian, Luo, Shue-Fen, Hsue, Yin-Tzu, Lan, Joung-Liang, Pan, Tai-Long, Wu, Yu-Ting, Yu, Kuang-Hui, Wei, Yau-Huei, Chang, Hen-Hong“…Background: Sjögren’s syndrome (SS) is an autoimmune inflammatory disease that primarily affects the exocrine glands, leading to glandular dysfunction. …”
Publicado 2021
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257“…In this paper, we seek to discuss the various methyltransferases that exist within single-stranded RNA (ssRNA) viruses along with their respective inhibitors. …”
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258por Krug, Sebastian, Mattheis, Laura, Haemmerle, Monika, Rosendahl, Jonas, Kleeff, Joerg, Michl, Patrick“…Recent approaches to classify HCC into different immunological states revealed a negative correlation between Wnt/ß‐catenin activation and immunogenicity and T‐cell infiltration. …”
Publicado 2021
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259“…Mechanisms and evolution of primary axis specification in insects are discussed in the context of the roles of ß-catenin and TCF in polarizing metazoan embryos. …”
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260por Gong, Yingdi, Fu, Yanping, Xie, Jiatao, Li, Bo, Chen, Tao, Lin, Yang, Chen, Weidong, Jiang, Daohong, Cheng, Jiasen“…Interestingly, expression of SsCut1 in plants can trigger defense responses, but it also enhanced plant susceptibility to SsCut1 gene knock-out mutants. …”
Publicado 2022
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