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  1. 341
    por Yu, Kai-Wei, Xue, Peng, Fu, Yang, Yang, Liang
    Publicado 2021
    “…The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely distributed in Gram-negative bacterial species. …”
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    T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation
  2. 342
    “…Additionally, we show that multiple smaller ssDNA scaffolds can efficiently substitute longer scaffolds in the formation of DNA origami.…”
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    One-Pot Synthesis of Defined-Length ssDNA for Multiscaffold DNA Origami
  3. 343
    “…We evaluated segmentations made with POnSS against a baseline of segmentations of the same data made conventionally in Praat. …”
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    A tool for efficient and accurate segmentation of speech data: announcing POnSS
  4. 344
    “…Whether type III secretion system (T3SS) effector proteins encoded by Gram-negative bacterial pathogens have intra-bacterial activities is an important and emerging area of investigation. …”
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    The T3SS Effector Protease NleC Is Active within Citrobacter rodentium
  5. 345
    “…BACKGROUND/AIM: Dipeptidyl peptidase-4 (DPP4) inhibitors, a class of oral antidiabetic drugs, have been shown to be protective on the vascular system because of their antiinflammatory, antiatherosclerotic, and vasodilatory effects. ß 2-adrenoceptors (ß 2-ARs) mediate the vasorelaxation in the aorta. …”
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    Effects of sitagliptin on ß-adrenoceptor mediated relaxation in streptozotocin-diabetic rat aorta
  6. 346
    “…Finally, we demonstrate the utility of these substrates for SM analysis of bidirectional growth of RAD-51-ssDNA filaments. For complete details on the use and execution of this protocol, please refer to Belan et al. (2021).…”
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    Generation of versatile ss-dsDNA hybrid substrates for single-molecule analysis
  7. 347
    “…To verify this important result that motivated the ‘biased agonist’ approach, we re-examined breathing in ß-arrestin 2-deficient mice and instead find no connection between ß-arrestin 2 and opioid respiratory depression. …”
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    ß-arrestin 2 germline knockout does not attenuate opioid respiratory depression
  8. 348
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    Protocol for the economic evaluation of the China Salt Substitute and Stroke Study (SSaSS)
  9. 349
    “…In the present experimental study, the effects of central injection of serotonin were investigated on LH concentration, KiSS1, adiponectin, and ghrelin genes expression. …”
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    Influences of Serotonin Hydrochloride on Adiponectin, Ghrelin and KiSS1 Genes Expression
  10. 350
    “…ssDNA recombineering has been exploited to hyperdiversify genomically-encoded nanobodies displayed on the surface of Escherichia coli for originating new binding properties. …”
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    ssDNA recombineering boosts in vivo evolution of nanobodies displayed on bacterial surfaces
  11. 351
    “…A subset of these bacteria uses a nanochannel called the type 4 secretion system (T4SS) to inject effector proteins that subvert the host cell machinery and drive the biogenesis of these compartments. …”
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    Undercover Agents of Infection: The Stealth Strategies of T4SS-Equipped Bacterial Pathogens
  12. 352
    “…By engineering a type VI secretion system (T6SS) that is controlled by an externally induced on/off switch, we transform the safe bacterium, Vibrio natriegens, into an effective antibacterial weapon. …”
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    Engineering a customizable antibacterial T6SS‐based platform in Vibrio natriegens
  13. 353
    “…Recently the structure of human CST was solved by cryo-EM, allowing the design of mutant proteins defective in telomeric ssDNA binding and prompting the reexamination of CST inhibition of telomerase. …”
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    CST does not evict elongating telomerase but prevents initiation by ssDNA binding
  14. 354
    “…Prediction accuracy of breeding values was compared between a classical BLUP and a single-step Genomic BLUP (ssGBLUP). Deregressed phenotypes were predicted. …”
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    ssGBLUP Method Improves the Accuracy of Breeding Value Prediction in Huacaya Alpaca
  15. 355
    “…ΔSspep1 mutants produced significantly less mycelium mass within infected plants. Additionally, SsPEP1 was identified as a potent inhibitor of sugarcane POD-1a peroxidase activity, implying that SsPEP1 may function to relieve reactive oxygen species-related stress within the host plant. …”
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    SsPEP1, an Effector with Essential Cellular Functions in Sugarcane Smut Fungus
  16. 356
    “…Here, we show that nanotubes formed from self-assembly of ssDNA-amphiphiles are stable in serum and nucleases. …”
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    ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival
  17. 357
    “…The ssDNA binding protein, RPA, not only protects the integrity of ssDNA, but also directs the downstream factor that signals or repairs the ssDNA intermediate. …”
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    Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble
  18. 358
    “…Previously, we showed that NrtR influences the T3SS expression and pathogenesis of Pseudomonas aeruginosa and demonstrated that NrtR mediates T3SS regulation through the cAMP/Vfr pathway. …”
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    NrtR Mediated Regulation of H1-T6SS in Pseudomonas aeruginosa
  19. 359
    “…To cope with some of these issues, we introduce here a novel framework, UPMaBoSS (for Update Population MaBoSS), dedicated to modeling dynamic populations of interacting cells. …”
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    UPMaBoSS: A Novel Framework for Dynamic Cell Population Modeling
  20. 360
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    Selection and Application of ssDNA Aptamers for Fluorescence Biosensing Detection of Malachite Green
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