“…The interaction mode of Irino molecules with ssDNA is electrostatic attraction via negative phosphate on the exterior of the ssDNA with Irino. …”
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“…The results show that the uniform corrosion rate of 304 SS increases after HAc addition but, with an increase in HAc concentration, the corrosion rate decreases. …”
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“…It has been proven to be effective in numerous preclinical disease models and some are currently in Phase II clinical trials. The ability of SS-31 to target the mitochondria makes SS-31 a potential therapy for tendinopathy. …”
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“…Correct pre-mRNA processing in higher eukaryotes vastly depends on splice site recognition. Beyond conserved 5′ss and 3′ss motifs, splicing regulatory elements (SREs) play a pivotal role in this recognition process. …”
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“…Experimental research into SS18-SSX biology has been limited by the lack of an antibody that specifically detects the endogenous fusion oncoprotein as opposed to its native SS18 or SSX components. …”
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“…After the visual inspection, SS-OCT scanning was performed onto the enamel surfaces to construct a 3D image. …”
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“…The quantification of ß-galactosidase activity is routinely required by laboratories worldwide. …”
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“…Map-based analysis of the RTL2 locus revealed that the rtl2 mutant possesses a single nucleotide substitution, which induces amino acid substitution Gly162 to Glu in the tryptophan synthase ß subunit 1 (TSB1). The TSB1 encodes an enzyme in tryptophan (Trp) biosynthetic pathway. …”
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“…Our findings expand our knowledge of V. fischeri T6SS ecology and identify a low-viscosity liquid condition where cells engage in contact-dependent killing. …”
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“…We investigated the spatiotemporal changes in strain associated with the occurrence of slow slip events (SSEs) in the subduction zones of the Japanese Islands and compared the spatial distribution of both the amount of strain accumulated for the period before and during the SSEs release using time series data from the Global Navigation Satellite System (GNSS). …”
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“…P2 × 4R is allosterically modulated by Zn(II), and despite the efforts to understand the mechanism, there is not a consensus proposal; C132 is a critical amino acid for the Zn(II) modulation, and this residue is located in the receptor head domain, forming disulfide SS3. To ascertain the role of the SS2/SS3 microenvironment on the rP2 × 4R Zn(II)-induced allosteric modulation, we investigated the contribution of each individual SS2/SS3 cysteine plus carboxylic acid residues E118, E160, and D170, located in the immediate vicinity of the SS2/SS3 disulfide bonds. …”
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“…The functional activity of T6SS requires 13 core components and T6SS accessory proteins, such as adapters containing DUF2169, DUF4123, and DUF1795 domains. …”
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“…Many studies on associations between human leukocyte antigen (HLA) alleles and RA have been reported, but few have been validated in RA subpopulations with anti-La/SS-B or anti-Ro/SS-A antibodies. Here, we investigated associations of HLA class II alleles with the presence of anti-Ro/SS-A or anti-La/SS-B antibodies in RA. …”
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