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461por Liebl, David, Robert-Genthon, Mylène, Job, Viviana, Cogoni, Valentina, Attrée, Ina“…The Gram-negative bacteria use the contractile multi-molecular structure, called the Type VI Secretion System (T6SS) to inject toxic products into eukaryotic and prokaryotic cells. …”
Publicado 2019
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462“…Here we identify a Vibrio antibacterial T6SS effector that contains a previously undescribed, widespread DNase toxin domain that we call PoNe (Polymorphic Nuclease effector). …”
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464por Torres Acosta, Juan Antonio, Michlmayr, Herbert, Shams, Mehrdad, Schweiger, Wolfgang, Wiesenberger, Gerlinde, Mitterbauer, Rudolf, Werner, Ulrike, Merz, David, Hauser, Marie-Theres, Hametner, Christian, Varga, Elisabeth, Krska, Rudolf, Berthiller, Franz, Adam, Gerhard“…Indeed, AtHSP90.1 and wheat TaHSP90-2 were inhibited by ZEN and ß-zearalenol, while α-zearalenol was almost inactive. …”
Publicado 2019
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465por Nguyen, Huong Van, Truong, Phung Minh, Duong, Huy Thuc, Dinh, Hiep Minh, Nguyen, Chuong Hoang“…We report here the biosynthesis of daidzein in Streptomyces sp. SS52, its genome sequence and the analysis of its genome for finding putative genes involved in daidzein biosynthesis. …”
Publicado 2019
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466por Kim, Si Eun, Lee, Byungju, Park, Seongbeom, Cho, Soo Hyun, Kim, Seung Joo, Kim, Yeshin, Jang, Hyemin, Jeong, Jee Hyang, Yoon, Soo Jin, Park, Kyung Won, Kim, Eun-Joo, Jung, Na Yeon, Yoon, Bora, Jang, Jae-Won, Hong, Jin Yong, Hwang, Jihye, Na, Duk L., Seo, Sang Won, Choi, Seong Hye, Kim, Hee Jin“…BACKGROUND: Although amyloid PET of typical Alzheimer’s disease (AD) shows diffuse ß-amyloid (Aß) deposition, some patients show focal deposition. …”
Publicado 2020
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467“…Wnt/ß-catenin signalling is crucial for maintaining the balance between cell proliferation and differentiation, both during tissue morphogenesis and in tissue maintenance throughout postnatal life. …”
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468por Callanan, J., Stockdale, S. R., Shkoporov, A., Draper, L. A., Ross, R. P., Hill, C.“…The first sequenced genome was that of the 3569-nucleotide single-stranded RNA (ssRNA) bacteriophage MS2. Despite the recent accumulation of vast amounts of DNA and RNA sequence data, only 12 representative ssRNA phage genome sequences are available from the NCBI Genome database (June 2019). …”
Publicado 2020
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469Selective ß2-Adrenoceptor Agonists and Relevant Hyperlactatemia: Systematic Review and Meta-Analysispor Liedtke, Alina G., Lava, Sebastiano A. G., Milani, Gregorio P., Agostoni, Carlo, Gilardi, Viola, Bianchetti, Mario G., Treglia, Giorgio, Faré, Pietro B.“…Selective ß(2)-agonists have been imputed as potential cause of l-hyperlactatemia since the 1970s. …”
Publicado 2019
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470“…Replication protein A (RPA) plays a critical role in all eukaryotic DNA processing involving single-stranded DNA (ssDNA). Contrary to the notion that RPA provides solely inert protection to transiently formed ssDNA, the RPA–ssDNA complex acts as a dynamic DNA processing unit. …”
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471por Liu, Kuo, Xi, Bo, Liu, Zheng, Qi, Han, Liu, Bin, Zhang, Jie, Cao, Han, Yan, Yuxiang, Zhao, Min, He, Yan, Zhang, Ling“…OBJECTIVES: Genome-wide association studies and candidate gene studies have found many single nucleotide polymorphisms (SNPs) that affect salt sensitivity (SS). We constructed a polygenic risk score (PRS) to estimate the joint effect of these SNPs on SS. …”
Publicado 2020
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472“…Here, we developed a new methodology that utilizes rolling circle replication and Cas9 mediated (RC-Cas-mediated) in vivo single strand DNA (ssDNA) synthesis. A single-gene rolling circle DNA replication system from Gram-negative bacteria was engineered to produce circular ssDNA from a Gram-positive parent plasmid at a designed sequence in Escherichia coli. …”
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473por Dow, Coad Thomas“…BCG is part of the standard of care for bladder cancer where, when given as an intravesicular irrigant, BCG acts as an immunomodulating agent and lessens the risk of recurrence. Mycobacterium avium ss. paratuberculosis (MAP) causes a fatal enteritis of ruminant animals and is the putative cause of Crohn’s disease of humans. …”
Publicado 2020
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474“…Using this approach, an ssDNA aptamer that binds to the nucleocapsid protein with a K(d) of 4.93 ± 0.30 nM was identified. …”
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475“…We previously identified Sclerotinia sclerotiorum negative-stranded virus 1 (SsNSRV-1), the first (−) ssRNA mycovirus, associated with hypovirulence of its fungal host Sclerotinia sclerotiorum. …”
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476por Zhao, Yune, Chen, Ding, Savini, Giacomo, Wang, Qing, Zhang, Hongfang, Jin, Yili, Song, Benhao, Ning, Rui, Huang, Jinhai, Mei, Chenyang“…PURPOSE: To assess the repeatability and reproducibility of swept-source optical coherence tomography (SS-OCT) and Scheimpflug system and evaluate the agreement between the two systems in measuring multiple corneal regions in children. …”
Publicado 2020
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477por Polak, Iwona, Łopieńska-Biernat, Elżbieta, Stryiński, Robert, Mateos, Jesús, Carrera, Mónica“…Ivermectin (IVM), an antiparasitic drug, has a positive effect against Anisakis simplex s.s. infection and has been used for the treatment and prevention of anisakiasis in humans. …”
Publicado 2020
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478por Smith, Emily C., Diedrich, André, Raj, Satish R., Gamboa, Alfredo, Shibao, Cyndya A., Black, Bonnie K., Peltier, Amanda, Paranjape, Sachin Y., Biaggioni, Italo, Okamoto, Luis E.Enlace del recurso
Publicado 2020
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479“…In this study, we evaluated the infiltration of immune cells in 101 osteosarcoma patients downloaded from TARGET using the ssGSEA to the RNA-sequencing of these patients, thus, high immune cell infiltration cluster, middle immune cell infiltration cluster and low immune cell infiltration cluster were generated. …”
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480por Wu, Hao, Zhang, Guoyun, Shen, Meixiao, Xu, Renchang, Wang, Pengqi, Guan, Zhenqi, Xie, Zhu, Jin, Zi, Chen, Sisi, Mao, Xinjie, Qu, Jia, Zhou, Xiangtian“…Macular choroidal thickness (ChT) and choroidal vascularity, including total choroidal area (TCA), luminal area (LA), stromal area (SA), and choroidal vascularity index (CVI), were determined from swept-source optical coherence tomography (SS-OCT) vertical and horizontal B-scans. The percentage of choriocapillaris flow voids (FV%) was obtained from en face SS-OCT-angiography. …”
Publicado 2021
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