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941por Davies, Kristen, Mirza, Kamran, Tarn, Jessica, Howard-Tripp, Nadia, Bowman, Simon J., Lendrem, Dennis, Ng, Wan-Fai“…Primary Sjögren’s syndrome (pSS) is a chronic autoimmune rheumatic disease with symptoms including dryness, fatigue, and pain. …”
Publicado 2019
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942por Wanthongcharoen, Suwanan, Yamprayoonswat, Wariya, Ruangsuj, Pattarawan, Thongpramul, Nuttida, Jumpathong, Watthanachai, Sittihan, Satapanawat, Kanjanavas, Pornpimon, Yasawong, Montri“…Haloferax volcanii SS0101 is a halophilic archaeon isolated from salt farms in Thailand. …”
Publicado 2019
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943por Portuondo, Deivys Leandro, Dores-Silva, Paulo Roberto, Ferreira, Lucas Souza, de Oliveira, Carlos S., Téllez-Martínez, Damiana, Marcos, Caroline Maria, de Aguiar Loesch, Maria Luiza, Guzmán, Fanny, Gava, Lisandra M., Borges, Júlio César, Pereira, Sandro Antonio, Batista-Duharte, Alexander, Carlos, Iracilda Zeppone“…Mice that were immunized with rSsEno plus PGA showed increased antibody titters against rSsEno and increased median survival time when challenged with S. brasiliensis as compared with mice that had not been immunized or that were immunized with rSsEno alone. …”
Publicado 2019
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944por Machiraju, Pranav, Wang, Xuemei, Sabouny, Rasha, Huang, Joshua, Zhao, Tian, Iqbal, Fatima, King, Melissa, Prasher, Dimple, Lodha, Arijit, Jimenez-Tellez, Nerea, Ravandi, Amir, Argiropoulos, Bob, Sinasac, David, Khan, Aneal, Shutt, Timothy E., Greenway, Steven C.“…Levels of cardiolipin were not significantly different between control and DCMA cells and were unaffected by SS-31 treatment. Our results demonstrate the abnormal mitochondria in fibroblasts from patients with DCMA and suggest that SS-31 may represent a potential therapy for this devastating disease.…”
Publicado 2019
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945por Windels, Etthel M., Ben Meriem, Zacchari, Zahir, Taiyeb, Verstrepen, Kevin J., Hersen, Pascal, Van den Bergh, Bram, Michiels, JanEnlace del recurso
Publicado 2019
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946
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947“…Here we investigated whether an impaired SAT lipolytic response coincides with an impaired SAT vitamin D release in eight lean and six obese men. 25‐hydroxyvitamin D(3) [25(OH)D(3)] and 1,25‐dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] fluxes across SAT were measured using arterio‐venous blood sampling in combination with AT blood flow measurements after an overnight fast and during 1‐hr intravenous infusion of the non‐selective ß‐adrenergic agonist isoprenaline (20 ng·kg FFM(−1)·min(−1)). 1,25(OH)(2)D(3) was released across abdominal SAT during isoprenaline infusion in lean [−0.01 (−0.04 to 0.00) pmol*100 g tissue(−1)*min(−1), p = .017 vs. zero flux], but not in obese men [0.01 (0.00 to 0.02) pmol*100 g tissue(−1)*min(−1), p = .116 vs. zero flux], and accompanied by an impaired isoprenaline‐induced lipolytic response in abdominal SAT of obese versus lean men. …”
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949“…BACKGROUND: Development of non-Hodgkin’s lymphoma (NHL) is the major adverse outcome of primary Sjögren’s Syndrome (pSS) affecting both morbidity and mortality. The high frequency of transformation to lymphoid malignancy in pSS among autoimmune rheumatic diseases (6–10% of patients) and the accessibility of the affected organ (minor salivary glands; MSG), render pSS an ideal model for the study of lymphomagenesis associated with autoimmune diseases and inflammation. …”
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950por Boon, Maarten, De Zitter, Elke, De Smet, Jeroen, Wagemans, Jeroen, Voet, Marleen, Pennemann, Friederike L, Schalck, Thomas, Kuznedelov, Konstantin, Severinov, Konstantin, Van Meervelt, Luc, De Maeyer, Marc, Lavigne, Rob“…We demonstrate that gp14, termed here as Drc (ssDNA-binding RNA Polymerase Cofactor), preferentially binds single-stranded DNA, yet contains a structural fold distinct from other ssDNA-binding proteins (SSBs). …”
Publicado 2020
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951“…BACKGROUND: The single-step single nucleotide polymorphism best linear unbiased prediction (ssSNPBLUP) is one of the single-step evaluations that enable a simultaneous analysis of phenotypic and pedigree information of genotyped and non-genotyped animals with a large number of genotypes. …”
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953por Cubillos-Zapata, Carolina, Martínez-García, Miguel Ángel, Díaz-García, Elena, Jaureguizar, Ana, Campos-Rodríguez, Francisco, Sánchez-de-la-Torre, Manuel, Nagore, Eduardo, Martorell-Calatayud, Antonio, Blasco, Luis Hernández, Pastor, Esther, Abad-Capa, Jorge, Montserrat, Josep María, Cabriada-Nuño, Valentín, Cano-Pumarega, Irene, Corral-Peñafiel, Jaime, Arias, Eva, Mediano, Olga, Somoza-González, María, Dalmau-Arias, Joan, Almendros, Isaac, Farré, Ramón, López-Collazo, Eduardo, Gozal, David, García-Río, FranciscoEnlace del recurso
Publicado 2020
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954por Alejaldre, Lorea, Lemay-St-Denis, Claudèle, Perez Lopez, Carles, Sancho Jodar, Ferran, Guallar, Victor, Pelletier, Joelle N.“…Introduction of substitutions E104K and G238S, that are known to have a synergistic effect on function in the parent ß-lactamase, showed similar increases in catalytic efficiency toward cefotaxime in the related ß-lactamases. …”
Publicado 2020
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955por Fashae, Kayode, Engelmann, Ines, Monecke, Stefan, Braun, Sascha D., Ehricht, RalfEnlace del recurso
Publicado 2021
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956por Drzmisek, Jakub, Stipl, Daniel, Petrackova, Denisa, Vecerek, Branislav, Dienstbier, Ana“…Furthermore, proteomic analysis identified BP2259 protein as a novel secreted T3SS substrate, which is required for T3SS functionality. …”
Publicado 2021
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957“…The cutoff value of less than 7.5 and 4.5 for CT-SS and CO-RADS, respectively, can rule out severe COVID-19 by 90% and 97%, respectively. …”
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958por Aworh, Mabel Kamweli, Kwaga, Jacob, Okolocha, Emmanuel, Harden, Lyndy, Hull, Dawn, Hendriksen, Rene S., Thakur, SiddharthaEnlace del recurso
Publicado 2020
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959por Mani, Cherish, Balasubramani, Sozharajan, Karthikeyan, Ramanujam, Kannan, Sathish“…Weld zone of all samples had less local stress and strain and SS 316L heat affected zone (HAZ) zone had more local stress and strain when compared to other zones. …”
Publicado 2021
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960por Brewin, John N., Rooks, Helen, Gardner, Kate, Senior, Harry, Morje, Mrinmayi, Patel, Hamel, Calvet, David, Bartolucci, Pablo, Thein, Swee-Lay, Menzel, Stephan, Rees, David C.Enlace del recurso
Publicado 2020
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